Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033036 (
APC
)
10,214
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
APC
8035
p53
803
Sep
657
CD4
598
Mol
529
TCR
518
MHC
493
anaphase-promoting complex/cyclosome
451
beta-catenin
445
cytokine
426
IFN-gamma
399
catenin
390
IL-2
375
CD8
374
MHC class II
356
ubiquitin
309
KRAS
302
ubiquitin ligase
293
cyclin
246
IL-4
239
CD28
221
IL-10
221
adenomatous polyposis coli
206
CTNNB1
196
proteasome
180
BRAF
179
CD40
168
E3 ubiquitin ligase
167
MHC class I
165
E-cadherin
164
p16
161
CD86
156
CDH1
153
lymphoid
148
CD80
144
securin
143
PTEN
135
MLH1
135
HLA
133
protein C
132
more...
Disease
APC
10214
cancer
2036
tumor
1833
colorectal cancer
925
familial adenomatous polyposis
632
carcinogenesis
493
tumorigenesis
480
carcinoma
409
colon cancer
345
adenoma
294
polyposis
282
adenocarcinoma
224
breast cancer
165
tumor progression
147
tumor growth
122
metastases
120
dysplasia
110
gastric cancer
109
Merkel cell carcinoma
97
Lynch syndrome
90
desmoid
89
influenza
86
HIV
85
ATM
83
prostate cancer
80
lung cancer
78
hepatocellular carcinoma
77
melanoma
76
diabetes
74
encephalomyelitis
74
systemic lupus erythematosus
73
ovarian cancer
73
leukemia
69
lymphoma
64
lupus
60
autoimmune disease
57
lupus
51
Hippel
51
virus infection
51
multiple sclerosis
50
more...
Symptom
pain
34
diarrhea
20
starvation
16
anesthesia
14
headache
14
constipation
13
seizures
11
abdominal pain
10
functional recovery
9
fatigue
9
vomiting
8
collapse
7
weakness
7
chills
7
chest pain
6
nausea
6
acidity
6
HSA
6
dyspnea
5
nausea and vomiting
5
exhaustion
5
splenomegaly
5
erythema
4
analgesia
4
angina
4
hypothermia
4
hypotonia
4
DNA marker
3
Ill
3
cough
3
hepatomegaly
3
thinning
3
flushing
3
agitation
3
physical appearance
3
fasciculation
2
sleepiness
2
intestinal bleeding
2
leg edema
2
spasticity
2
more...
Drug
IFN-gamma
398
IL-2
375
CSF
90
lysine
43
CPT-11
24
Dermatol
22
MAP
19
caffeine
18
Irinotecan
17
Cardiovasc
14
PTC
13
Monit
12
Adriamycin
11
Asn
11
EPA
10
G-CSF
8
ROS
8
Gel
7
ROC
7
BLM
7
MDS
7
Leaf
7
CAM
7
CIA
7
CaCl2
6
ZnO
6
Bevacizumab
6
Ximelagatran
6
CaCl2
6
CaCl2
6
ENT
6
FeCl3
6
Valdecoxib
6
vitamin E
5
CTX
5
Taxol
5
CTC
5
uPA
5
TAT
5
CTC
4
more...
Enzyme
APC
8035
ERK
269
proteasome
183
protein kinase
165
mitogen-activated protein kinase
132
thrombin
107
focal adhesion kinase
84
renin
81
cdc2
65
GSK
55
protein kinase C
49
polo-like kinase 1
49
adenylate cyclase
49
lysozyme
49
STK11
45
separase
42
thromboplastin
39
MEK
38
luciferase
36
calcineurin
34
PRA
30
trypsin
27
caspase-3
25
PARP
24
ATPase
21
phospholipase C
19
RNA polymerase
19
glutathione S-transferase
18
reverse transcriptase
17
granzyme B
17
ACS
16
DNA polymerase
16
ubiquitin-protein ligase
16
catalase
16
pyruvate decarboxylase
15
pyruvate dehydrogenase
15
tissue plasminogen activator
15
tryptase
15
alkaline phosphatase
14
DNA methyltransferase
14
more...
Compound
Pac
2065
PAC
2056
DNA
1301
Dec
736
Clin
339
water
233
calcium
153
sodium
130
DCC
128
tyrosine
110
oxygen
100
aldosterone
97
TNF
81
arginine
81
glucose
72
lysine
65
cAMP
63
serine
59
FAP
58
FAP
58
sulfate
57
methionine
55
nitrogen
53
cysteine
50
potassium
47
threonine
47
alanine
46
phosphate
45
salt
43
His
42
urea
39
hydrogen
39
PMA
38
ATP
36
PMA
36
aluminum
34
acetate
31
zinc
31
NKT
31
galactose
30
more...