Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033036 (APC)
 10,214 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
APC 8035
p53 803
Sep 657
CD4 598
Mol 529
TCR 518
MHC 493
anaphase-promoting complex/cyclosome 451
beta-catenin 445
cytokine 426
IFN-gamma 399
catenin 390
IL-2 375
CD8 374
MHC class II 356
ubiquitin 309
KRAS 302
ubiquitin ligase 293
cyclin 246
IL-4 239
IL-10 221
CD28 221
adenomatous polyposis coli 206
CTNNB1 196
proteasome 180
BRAF 179
CD40 168
E3 ubiquitin ligase 167
MHC class I 165
E-cadherin 164
p16 161
CD86 156
CDH1 153
lymphoid 148
CD80 144
securin 143
PTEN 135
MLH1 135
HLA 133
protein C 132
K-ras 131
DCC 128
PIK3CA 128
BRCA1 123
LPS 123
IFN 121
SMAD4 114
RASSF1A 111
thrombin 109
IL-6 108
Mad2 104
Axin 104
cyclin B1 103
TNF-alpha 103
pituitary adenylate cyclase-activating polypeptide 101
MCC 97
protein S 96
HLA-DR 96
SCF 96
CDKN2A 95
cyclin D1 94
factor V 94
CD11c 94
tumour suppressor 93
methylguanine-DNA methyltransferase 92
ICAM-1 91
TCF 88
thymus 86
BRCA2 84
MSH2 84
FISH 83
hMLH1 83
MUTYH 82
GSTP1 82
renin 81
TNF 81
ras 79
ATM 79
EGFR 77
insulin 77
CD25 76
prothrombin 76
p21 75
APC protein 74
factor V Leiden 73
phosphatase 72
MAPK 72
MLR 71
TGF-beta 71
gut 70
CD45 68
telomeric 68
KEN 67
RB1 67
GM-CSF 66
LFA-1 65
CD40L 64
IL-1 63
IL-5 63
PI3K 63
cyclin A 61
CTLA-4 61
CDC20 60
CD11b 60
CD44 59
FAP 58
MSH6 58
T cell receptor 58
Cyclin 57
polypeptide 55
c-myc 54
cyclin-dependent kinase 54
CD2 52
histone 52
GSK 52
myelin basic protein 52
IL-17 51
CD14 51
Skp2 49
lysozyme 49
adenylate cyclase 49
COX-2 49
MYC 48
chemokine 47
FBXW7 47
annexin V 47
fused 46
CD40 ligand 46
VHL 45
NRAS 45
STK11 45
CD83 44
cadherin 44
B7-2 44
MYH 44
B7-H3 43
separase 43
antithrombin 43
glycoprotein 42
AXIN2 42
IgE 41
SFRP1 41
PMS2 41
collagen 41
FZR1 41
DAPK 40
TIMP3 40
colon carcinoma 40
lymphokine 39
CD69 39
Bcl-2 39
INK4a 39
p14 39
NMR 39
cage 38
AKT 38
TLR4 37
c-Myc 37
ATP 36
autoantigen 36
more...
Disease
APC 10214
cancer 2036
tumor 1833
colorectal cancer 925
familial adenomatous polyposis 632
carcinogenesis 493
tumorigenesis 480
carcinoma 409
colon cancer 345
adenoma 294
polyposis 282
adenocarcinoma 224
breast cancer 165
tumor progression 147
tumor growth 122
metastases 120
dysplasia 110
gastric cancer 109
Merkel cell carcinoma 97
Lynch syndrome 90
desmoid 89
influenza 86
HIV 85
ATM 83
prostate cancer 80
lung cancer 78
hepatocellular carcinoma 77
melanoma 76
encephalomyelitis 74
diabetes 74
ovarian cancer 73
systemic lupus erythematosus 73
leukemia 69
lymphoma 64
lupus 60
autoimmune disease 57
virus infection 51
Hippel 51
lupus 51
multiple sclerosis 50
squamous cell carcinoma 41
primary tumor 41
ulcerative colitis 41
tetanus 41
non-small cell lung cancer 40
colitis 40
epithelial ovarian cancer 40
rectal cancer 39
retinoblastoma 39
HNPCC 39
stroke 39
hypertension 39
cold 39
Barrett's esophagus 38
Gardner's syndrome 38
infectious diseases 38
deep vein thrombosis 37
inflammatory bowel disease 37
pancreatic cancer 37
type 1 diabetes 36
Mycobacterium 36
PHA 33
asthma 33
NOD 32
hepatoblastoma 31
tuberculosis 30
sepsis 29
Alzheimer's disease 29
WT1 29
Activated protein C resistance 28
mental retardation 28
tumor initiation 28
mental retardation 28
medulloblastoma 27
sepsis 27
STS 27
anemia 26
hepatitis B 26
bladder cancer 26
papillary thyroid cancer 26
acute myeloid leukemia 25
ischemia 25
AIDS 25
Peutz-Jeghers syndrome 25
arthritis 25
ARF 24
SCID 24
immunodeficiency 24
rheumatoid arthritis 23
residual disease 23
familial cancer 23
multiple myeloma 23
glioblastoma 23
neuroblastoma 22
graft-versus-host disease 22
liver cancer 22
endometrial cancer 22
cervical cancer 22
liver cancer 21
glioma 21
vaccinia 21
SDS 21
SEM 21
essential hypertension 20
cirrhosis 20
aldosteronism 20
sarcoma 20
Turcot syndrome 20
myelodysplastic syndrome 20
lung carcinoma 20
Blocking 20
thyroid cancer 19
acute lymphoblastic leukemia 19
fibromatosis 19
esophageal cancer 19
obesity 19
B-cell lymphoma 19
lymphocytic choriomeningitis 19
Colorectal Cancer 19
MCF 19
pertussis 18
plaque 18
supraventricular tachycardia 18
renal cell carcinoma 18
immunopathology 18
liver metastases 18
DBA 18
myocardial infarction 18
flutter 18
Pituitary 17
aggressiveness 17
Crohn's disease 17
esophageal cancer 17
MEN1 17
osteosarcoma 16
eosinophilia 16
atherosclerosis 16
Epstein 16
depression 16
hepatitis 16
hepatitis C 16
heart disease 15
Colon 15
HCG 15
Colon 15
neutropenia 15
mammary tumor 15
intestinal cancer 15
Colon 15
neoplastic transformation 15
malaria 15
abortion 15
Colon cancer 14
cholera 14
chronic myeloid leukemia 14
Hodgkin's disease 14
coronary artery disease 14
gastrointestinal cancer 14
pheochromocytoma 14
Dukes 13
more...
Symptom
pain 34
diarrhea 20
starvation 16
headache 14
anesthesia 14
constipation 13
seizures 11
abdominal pain 10
fatigue 9
functional recovery 9
vomiting 8
chills 7
weakness 7
collapse 7
chest pain 6
acidity 6
nausea 6
HSA 6
dyspnea 5
nausea and vomiting 5
exhaustion 5
splenomegaly 5
hypotonia 4
analgesia 4
erythema 4
angina 4
hypothermia 4
cough 3
hepatomegaly 3
Ill 3
physical appearance 3
agitation 3
flushing 3
DNA marker 3
thinning 3
fasciculation 2
intestinal bleeding 2
sleepiness 2
spasticity 2
leg edema 2
shortness of breath 2
blurred vision 1
bloating 1
Gasping 1
discomfort 1
anorexia 1
cachexia 1
ENT 1
bigeminal 1
memory loss 1
pallor 1
trigeminy 1
stridor 1
cerebellar ataxia 1
anal pain 1
hypercapnia 1
cancer pain 1
Wind 1
syncopal episodes 1
Cri du chat 1
despair 1
dry eye 1
lethargy 1
decreased appetite 1
Sedation 1
clumsiness 1
hypertonia 1
discomfort 1
twitching 1
tinnitus 1
overweight 1
exertional angina 1
Respiratory symptoms 1
colic 1
respiratory distress 1
hemiplegia 1
ataxia 1
bewilderment 1
hyperacusis 1
stigma 1
torticollis 1
epigastric pain 1
back pain 1
apathy 1
numbness 1
chest tightness 1
impaired motor coordination 1
hemoptysis 1
Functional constipation 1
chronic constipation 1
Drug
IFN-gamma 398
IL-2 375
CSF 90
lysine 43
CPT-11 24
Dermatol 22
MAP 19
caffeine 18
Irinotecan 17
Cardiovasc 14
PTC 13
Monit 12
Asn 11
Adriamycin 11
EPA 10
ROS 8
G-CSF 8
MDS 7
Leaf 7
CAM 7
Gel 7
CIA 7
BLM 7
ROC 7
ENT 6
Ximelagatran 6
CaCl2 6
CaCl2 6
FeCl3 6
CaCl2 6
ZnO 6
Valdecoxib 6
Bevacizumab 6
CTC 5
vitamin E 5
TAT 5
Taxol 5
CTX 5
uPA 5
Gleevec 4
PCP 4
IFN-beta 4
Asthma 4
ACT 4
Parkin 4
p75 4
THF 4
Nephron 4
CTC 4
Captopril 4
IL-11 4
Carotenoid 4
G418 4
Parkin 4
Copaxone 4
NH3 4
Imatinib 4
L-tyrosine 3
TAC 3
Meth 3
SMP 3
ascorbate 3
ABC 3
Phosphatidylserine 3
ETS 3
DM1 3
Docetaxel 3
Gefitinib 3
Activin 3
DMAP 3
Abatacept 3
FCV 3
Paraffin 3
Nesiritide 3
PCB 3
Vioxx 3
nitroglycerin 3
FAD 3
Forskolin 3
Provenge 3
EPI 3
-deoxyadenosine 3
ADR 3
GRF 3
CTA 3
ADM 3
CCL 3
EE2 3
Bifidobacterium 3
Capsicum 3
Imiquimod 2
Fluorescein 2
Amoxicillin 2
CTX 2
Caspofungin 2
OMP 2
APM 2
DEL 2
PFA 2
lactose 2
CDX 2
CED 2
CTX 2
Fraction 2
Efalizumab 2
NAG 2
TAK 2
Natalizumab 2
Cetuximab 2
ICI 2
Efalizumab 2
Aloe 2
Lovastatin 2
Portal 2
Calcipotriol 2
ALA 2
Edodekin alfa 2
Darbepoetin alfa 2
Zofenopril calcium 2
VCR 2
Heme 2
MOF 2
Pegasys 2
Epoetin 2
Clonidine 2
CPR 2
CDX 2
Methylene blue 2
Triclosan 2
Rasagiline 2
ampicillin 2
Spectrum 2
Ranolazine 2
Mutagen 2
Ranolazine 2
Vitamin E 2
TEL 2
Kaolin 2
Ethanol 2
CDP 2
CPZ 1
Digitalis 1
Bactrim 1
HCG 1
Fulvestrant 1
Erlotinib 1
Vandetanib 1
Tetanus toxoid 1
Methylprednisolone 1
Cimetidine 1
Urokinase 1
citric acid 1
Galactose 1
9-THC 1
Thyroglobulin 1
TRM 1
Lipitor 1
Bexarotene 1
Genasense 1
MDM 1
more...
Enzyme
APC 8035
ERK 269
proteasome 183
protein kinase 165
mitogen-activated protein kinase 132
thrombin 107
focal adhesion kinase 84
renin 81
cdc2 65
GSK 55
adenylate cyclase 49
lysozyme 49
protein kinase C 49
polo-like kinase 1 49
STK11 45
separase 42
thromboplastin 39
MEK 38
luciferase 36
calcineurin 34
PRA 30
trypsin 27
caspase-3 25
PARP 24
ATPase 21
RNA polymerase 19
phospholipase C 19
glutathione S-transferase 18
granzyme B 17
reverse transcriptase 17
ACS 16
catalase 16
ubiquitin-protein ligase 16
DNA polymerase 16
tryptase 15
pyruvate dehydrogenase 15
tissue plasminogen activator 15
pyruvate decarboxylase 15
neuraminidase 14
MAP 14
alkaline phosphatase 14
DNA methyltransferase 14
RNase 13
PAM 13
NO synthase 13
RNase 13
phospholipase A2 12
superoxide dismutase 12
CD10 12
phosphatidylinositol 3-kinase 11
MMP 11
beta-galactosidase 10
protein phosphatase 2A 10
PAH 10
topoisomerase 10
peroxidase 10
CaMKII 10
kinesin 10
carboxylesterase 10
AMPK 9
transcriptase 9
CYP3A4 9
deaminase 9
beta-glucuronidase 8
urokinase-type plasminogen activator 8
plasmin 8
topoisomerase 8
phosphodiesterase 8
AMP-activated protein kinase 8
MIP 7
methylenetetrahydrofolate reductase 7
prostate-specific antigen 7
collagenase 7
kallikrein 7
cathepsin D 7
methylenetetrahydrofolate reductase 7
gamma-glutamyl transpeptidase 7
endonuclease 6
PAL 6
thymidine kinase 6
cathepsin S 6
ACE 6
aspartate aminotransferase 6
AMPK 6
ricin 5
P-glycoprotein 5
PAL 5
glutaminase 5
ribonuclease 5
tyrosinase 5
cathepsin L 5
PDK1 5
cathepsin B 5
ribonuclease 5
TAT 5
arginase 4
CD13 4
CPT 4
CPT 4
CPT 4
TSA 4
ornithine decarboxylase 4
thyroid peroxidase 4
glutathione peroxidase 4
glutamine synthetase 4
SMP 4
TGT 4
PCP 4
BAT 4
MEKK1 4
acylase 4
phospholipase D 4
proteinase K 3
guanylate cyclase 3
penicillin acylase 3
histone acetyltransferase 3
acetolactate synthase 3
chloramphenicol acetyltransferase 3
acetylcholinesterase 3
ATP synthase 3
insulin-degrading enzyme 3
glyceraldehyde-3-phosphate dehydrogenase 3
alanine aminopeptidase 3
demethylase 3
dihydrofolate reductase 3
caspase-8 3
ribonucleotide reductase 3
acid phosphatase 3
ribonucleotide reductase 3
NOS 3
MDR 3
caspase-1 3
ADP-ribosyltransferase 3
glucose-6-phosphate dehydrogenase 3
chaperonin 3
papain 3
UDP-glucuronosyltransferase 3
ADP-ribosyltransferase 3
DNA ligase 3
DNA ligase 3
HSD 3
pepsin 3
prostaglandin synthetase 3
choline acetyltransferase 3
hypoxanthine-guanine phosphoribosyltransferase 3
CNPase 3
chymotrypsin 3
tyrosine hydroxylase 2
TSR 2
alpha-galactosidase 2
ascorbate peroxidase 2
lactate dehydrogenase 2
furin 2
TSP-1 2
beta-lactamase 2
carbonic anhydrase 2
methionine synthase 2
histone demethylase 2
caspase-7 2
PNGase F 2
more...
Compound
Pac 2065
PAC 2056
DNA 1301
Dec 736
Clin 339
water 233
calcium 153
sodium 130
DCC 128
tyrosine 110
oxygen 100
aldosterone 97
arginine 81
TNF 81
glucose 72
lysine 65
cAMP 63
serine 59
FAP 58
FAP 58
sulfate 57
methionine 55
nitrogen 53
cysteine 50
potassium 47
threonine 47
alanine 46
phosphate 45
salt 43
His 42
hydrogen 39
urea 39
PMA 38
PMA 36
ATP 36
aluminum 34
zinc 31
NKT 31
acetate 31
ammonium 30
galactose 30
SN-38 29
MTT 29
nitric oxide 29
NH2 28
GTP 28
leucine 27
iodine 26
MEK 26
CPT-11 24
benzaldehyde 23
benzaldehyde 23
PAS 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
iron 22
aldehyde 22
Asp 22
SDS 21
PEG 21
proline 21
Ubiquitin 20
ACTH 20
BCR 20
Phe 20
creatinine 20
ammonia 20
ethanol 19
caffeine 18
copper 18
DBA 18
5-aminopentanoic acid 18
DBA 17
DBA 17
PGE2 17
glutamine 17
noradrenaline 17
ACS 17
retinoic acid 17
ADP 16
ACS 16
DOC 16
Cardiol 16
ADP 16
PAM 16
aldehyde 16
ADP 16
methanol 16
MAP 15
Ile 15
bromide 14
pyridine 14
PGE 14
TAP 14
Thrombin 13
chlorine 13
AMP 13
PCI 13
Gly 13
MDA 13
palmitic acid 12
PAM 12
PAM 12
aspartic acid 12
Adriamycin 12
PEG 12
ASA 12
Cbl 12
Optimal 11
aspartic acid 11
DDP 11
aspartic acid 11
silver 11
formaldehyde 11
TNM 11
aspartic acid 11
glutamate 10
acetonitrile 10
carbonate 10
vitamin D 10
PAH 10
ABL 10
EPA 10
MCH 10
TEM 10
5-FU 10
benzene 9
CAT 9
CAT 9
BLM 9
COX 9
acetic acid 9
THP 9
more...