Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033036 (
APC
)
10,214
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Experimental and literary data on the peculiarities of complement alternative pathway (
APC
) self-regulation and regulation are reviewed. There is a discussion of the methods of
APC
evaluation, including a new one, called complement hemolytical capacity. It is shown that the duration of complement-dependent hemolysis lag-period is limited by
factor D
concentration. The phenomenon of acceleration of
APC
-dependent hemolysis by membranes of lysed cells is described. The latter is an evidence of
APC
functioning in the mode of double amplification.
...
PMID:[Novel approaches to the study of autoregulation of alternative complement pathway]. 991 67
