Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033036 (APC)
 10,214 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In previous studies (Shikwa Gakuho 80: 473-485, 1471-1486, 1980), the authors have reported on sealing properties in vitro. But the recent development of many new sealers makes necessary a detailed reexamination at this time. The experimental materials were as follows; Zinc oxide eugenol sealer......Canals Calcium hydroxide eugenol sealer......CRCS, Dentalis KEZ Calcium hydroxide guaiacol sealer......FR Hydroxyapatite sealer......Finapec APC, Apatite root sealer TYPE III The experimental procedure employing a glass tube and the dye-penetration method was similar to the one used in previous studies. Results of the investigation; 1. Degrees of dye penetration were classified into 3 types i) Immediate penetration through the zone between the material and the glass tube within 2 days.--Apatite root sealer TYPE III, Dentalis KEZ ii) Little penetration within 12 hours but gradual penetration to the deep zone thereafter.--CRCS, Canals iii) Slight penetration within 7 days and then gradual penetration 1/5 of the way through the zone between the material and the glass tube.--Finapec APC 2. Dye penetrated through the material in the case of apatite root sealer TYPE III and FR.
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PMID:[Experimental studies on the sealing properties of various kinds of root canal sealers in vitro (Part 3)]. 262 93

DISORDER: Familial adenomatous polyposis coli. ETHNICITY OF PATIENT: Japanese. GENE: APC. GENBANK ACCESSION NUMBER: M 74088. CHROMOSOMAL ASSIGNMENT: 5q21. TYPE OF DNA VARIANT: A germline missense mutation. A germline nonsense mutation. MUTATION: CGG (Arg, wild type) to TGG (Trp) substitution at codon 88 in exon 3 of the APC gene. CGA (Arg, wild type) to TGA (term.) at codon 213 in exon 5 of the APC gene. ALLELIC FREQUENCY: <0.014 (missense mutation, TGG at codon 88). METHOD OF MUTATION DETECTION: PCR-SSCP/direct sequencing.
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PMID:A novel non-pathogenetic polymorphism of the APC gene in a patient with familial adenomatous polyposis coli. 1083 Sep 91