Gene/Protein Disease Symptom Drug Enzyme Compound
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The relationship between stroke volume (SV) measured simultaneously by impedance cardiography (SVI) and echocardiography (SVE) has been analyzed. Change in stroke volume in 6 healthy volunteers was induced by passive head-up tilting (80 degrees) and by oral administration of the sympathomimetic drug amezinium. A correlation of r = 0.83 (p much less than 0.01) was found between SVI and SVE calculated by the equation: SVE = 16.0 + (0.528 x SVI). Though stroke volume is overestimated by impedance cardiography, the method may be useful for the clinical pharmacologist interested in a simple non-invasive tool to estimate stroke volume and change in it.
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PMID:Comparison of impedance cardiography and echocardiography for measurement of stroke volume. 716 Apr 14