Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0032617 (polyuria)
 3,056 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Aquaporin-2 mutant 12.3
AVP-NPII 12.1
AQP2 protein 11.1
AVPR2 10.9
bumetanide-sensitive Na-K-2Cl cotransporter 10.8
claudin 16 10.7
CLDN19 10.7
KCNJ1 10.6
arginine vasopressin V2 receptor 10.5
vacuolar protein sorting 33B 10.5
SLC12A1 10.5
aquaporin 2 10.5
arginine vasopressin-neurophysin II 10.3
CLCNKB 10.2
AQP2 10.0
ARHGAP4 10.0
glutamate decarboxylase GAD65 9.9
barttin 9.8
Claudin-16 9.8
MAGE-D 9.6
MAGED2 9.6
Gb3 synthase 9.6
SCTR 9.5
A4GALT 9.4
NKCC2 9.4
CLCNKA 9.3
NDST3 9.2
nephrocystin-4 9.2
NPHP4 9.1
NPH1 9.0
aquaporin 7 9.0
claudin-19 9.0
SLC5A2 8.9
SLC12A3 8.9
AQP3 protein 8.9
NPHP3 8.9
aldesleukin 8.8
nephrocystin 8.8
ATP6V1B1 8.8
AQP3 8.7
NDI 8.6
nephropathic cystinosis 8.6
insulinoma-associated protein 2 8.5
SI1 8.5
Cystinosis 8.5
ROMK 8.5
Tonicity-responsive enhancer binding protein 8.4
PCBD 8.4
ARPKD 8.4
zinc transporter 8 8.3
HLA-DR beta chain 8.3
aquaporin 8.2
arginine vasopressin 8.2
ATP6V0A4 8.1
ClC-K2 8.1
collecting duct 8.1
CLDN10 8.1
CTNS 8.1
hepatocyte nuclear factor 1 alpha 8.1
panhypopituitarism 8.1
sodium/hydrogen exchanger 8.1
NPHP2 8.0
NPHP1 8.0
claudin-10 8.0
collectrin 8.0
AQP1 7.9
vasopressin 7.9
PAX4 7.9
sodium-potassium-chloride cotransporter 7.9
UT-A2 7.8
SLC2A2 7.8
water channel 7.7
oxytocinase 7.7
ADH 7.6
TRPC3 protein 7.5
BSC-1 7.5
BSC1 7.4
Angiotensin I converting enzyme 7.4
AVP 7.4
NCCT 7.4
more...
Disease
Pancreatic islet cell adenoma 13.3
Renal adenoma and carcinoma 13.3
metastatic squamous cell carcinoma of the nasopharynx 13.3
Congenital Mesoblastic Nephroma 13.3
Acute toxic nephropathy 12.3
Acquired nephrogenic diabetes insipidus 12.3
Prepyloric ulcer 12.3
Hypokalemic hypochloremic metabolic alkalosis 12.3
Congenital nephrogenic diabetes insipidus 12.0
Central diabetes insipidus 11.9
Primary polydipsia 11.9
Salmonella paratyphi infection 11.8
Familial nephropathy 11.8
Secondary diabetes mellitus 11.8
Sudden acquired retinal degeneration 11.8
Gallbladder mucocele 11.8
Acute nephropathy 11.8
nephrogenic diabetes insipidus 11.5
parathyroid chief cell adenoma 11.3
Congenital rubella infection 11.3
adult craniopharyngioma 11.3
Renal hematuria 11.3
Pancreatic mass 11.3
Other endocrine disorders 11.0
Visceral gout 11.0
Diuretic abuse 11.0
Acquired Fanconi syndrome 11.0
Osmotic nephrosis 10.8
Starvation ketoacidosis 10.8
Steroid-induced diabetes 10.8
MCKD2 10.8
Multiple renal cysts 10.8
diabetes insipidus 10.5
MCKD1 10.4
juxtaglomerular cell hyperplasia 10.4
BSND 10.4
Bacterial cystitis 10.3
Psychogenic polydipsia 10.3
Fanconi-like syndrome 10.2
Chronic hypokalemia 10.2
autoimmune endocrine disorder 10.2
mental developmental delay 10.0
swelling of the pituitary gland 10.0
Bartter's syndrome 10.0
Streptococcus bovis infection 9.9
childhood craniopharyngioma 9.8
Adenomatous goiter 9.8
Lymphocytic hypophysitis 9.7
congenital hyperbilirubinemia 9.6
Acute myopathy 9.6
Focal motor seizures 9.6
Hypervitaminosis D 9.6
hypokalemic alkalosis 9.6
hypernatremia 9.6
Motor neuropathy 9.5
Diencephalic syndrome 9.4
aminoaciduria 9.4
nocturia 9.4
Nephropathia epidemica 9.4
Mauriac syndrome 9.3
X-linked hereditary disease 9.3
Celiac crisis 9.2
ADH decreased 9.2
Gitelman syndrome 9.2
NPHP4 9.1
CNS germinoma 9.1
Hyponatremic 9.1
IgA gammopathy 9.1
TINU 9.0
Febrile illness 9.0
hypochloremia 9.0
antidiuresis 9.0
Azotemia 8.9
metastatic parathyroid carcinoma 8.9
parathyroid neoplasm 8.9
nephrocalcinosis 8.8
Hypophysitis 8.8
Pacheco's disease 8.8
Chlamydia pneumoniae pneumonia 8.8
pituitary chromophobe adenoma 8.8
more...
Symptom
polyuria 13.3
polydipsia 12.6
generalised tiredness 11.8
nocturnal polyuria 11.0
CVA tenderness 10.5
Chronic vomiting 10.3
excessive urination 10.3
Pituitary enlargement 9.4
ketonuria 9.3
GI pain 9.1
dysorexia 9.0
intestinal pain 8.8
oliguria 8.3
renal pain 8.3
hyperosmia 8.2
lassitude 8.0
enuresis 7.9
carpopedal spasm 7.8
epigastric distress 7.8
stomach cramps 7.8
General symptoms 7.5
bedwetting 7.5
adipsia 7.4
painful swallowing 7.3
lethargy 7.3
urinary frequency 7.1
frequent urination 6.9
emaciation 6.9
sighing 6.7
thirsty 6.6
phosphatemia 6.6
Visual disturbances 6.5
anorexia 6.3
dysuria 6.1
tenesmus 6.0
renal colic 6.0
precordial pain 5.9
abdominal cramps 5.9
hyperemesis gravidarum 5.8
Lower urinary tract symptoms 5.8
decreased appetite 5.7
bradypnea 5.7
labored breathing 5.6
vomiting 5.6
rales 5.6
pedal edema 5.6
asthenia 5.6
bone pain 5.5
photophobia 5.5
disturbed balance 5.5
aphonia 5.4
dry skin 5.4
tingling 5.4
blurred vision 5.3
constipation 5.3
nasal discharge 5.3
tachypnea 5.2
night sweats 5.1
muscle cramps 5.1
weakness 5.1
pallor 5.0
nausea 5.0
Physical findings 5.0
leg edema 5.0
right upper quadrant pain 4.9
flank pain 4.8
prostration 4.8
Ill 4.8
loss of taste 4.8
bladder pain 4.7
hepatomegaly 4.7
clubbing 4.5
dizziness 4.5
fatigue 4.4
stomach pain 4.4
apathy 4.3
lightheadedness 4.3
colic 4.3
clumsiness 4.3
abdominal pain 4.3
more...
Drug
Nivazol 11.3
Pitressin tannate 10.2
Demeclocycline 9.5
Lixivaptan 9.3
Amikacin sulfate 9.1
Bendazac 9.1
DDAVP 9.0
DDAVP 9.0
Tolvaptan 8.9
Carmofur 8.7
Pitressin 8.6
Conivaptan 8.0
Desmopressin acetate 7.9
Lantus 7.6
Potassium citrate 7.6
Trilostane 7.6
Parecoxib 7.5
Velban 7.1
Gallium nitrate 7.0
Rasburicase 6.9
Insulin detemir 6.9
Insulin glargine 6.8
Plavix 6.4
Dexfenfluramine 6.4
Sulprostone 6.4
Cilazapril 6.2
Vioxx 6.2
Ramipril 6.2
Sulpiride 6.1
Tenofovir disoproxil fumarate 5.9
Gatifloxacin 5.8
Medetomidine 5.7
Tenofovir 5.7
Diamminedichloroplatinum 5.6
Mesalazine 5.5
Ammonium chloride 5.5
Rasburicase 5.4
metformin hydrochloride 5.3
PMPA 5.3
Aliskiren 5.3
Indomethacin 5.3
Prednisolone 5.1
Amiloride 5.1
Levosimendan 5.1
Duloxetine 5.1
Mirtazapine 5.1
Prednisone 4.9
Enrofloxacin 4.9
Amiloride 4.8
Zonisamide 4.8
Hydrochlorothiazide 4.7
Bosentan 4.6
Bosentan 4.6
Tocilizumab 4.6
Liraglutide 4.6
PTH 4.5
Nephron 4.5
MTC 4.4
PFA 4.4
Sinemet 4.3
Denosumab 4.2
Clopidogrel 4.2
Clofibrate 4.2
Etoposide 4.2
Fructose 4.0
Domperidone 4.0
Colistin 3.9
Nephron 3.9
ETA 3.9
DMSA 3.8
Rosiglitazone 3.7
Diurnal 3.6
Amoxicillin 3.5
Sodium nitroprusside 3.4
Galactose 3.3
Acyclovir 3.3
Doxycycline 3.3
Captopril 3.2
Methylene blue 3.0
Fluconazole 3.0
more...
Enzyme
proprotein convertase 1 7.8
ADH 7.6
D-amino-acid oxidase 7.1
CDP-diacylglycerol synthase 6.7
alanine aminopeptidase 5.8
alcohol dehydrogenase 5.7
uridyltransferase 5.6
oxytocinase 5.5
renin 5.3
PRA 5.2
glycerophosphate acyltransferase 5.1
methylmalonyl-CoA mutase 4.7
N-acetylglucosaminyltransferase 4.4
angiotensin-converting enzyme 2 4.3
thyroid peroxidase 4.3
aromatic L-amino acid decarboxylase 4.3
thromboxane synthase 4.2
prostaglandin synthetase 4.1
glucose-6-phosphatase 4.1
galactokinase 4.1
p-nitrophenylphosphatase 4.1
STR 4.0
11beta-hydroxysteroid dehydrogenase 4.0
aldose reductase 4.0
asparaginase 4.0
3-hydroxyacyl-CoA dehydrogenase 3.9
glucokinase 3.9
PAH 3.8
dipeptidyl peptidase IV 3.6
pyruvate kinase 3.6
diacylglycerol acyltransferase 3.6
phosphorylase kinase 3.5
CD13 3.5
ACE 3.4
diacylglycerol kinase 3.4
kallikrein 3.4
gamma-glutamyl transpeptidase 3.2
15-lipoxygenase 3.2
aspartate aminotransferase 3.1
lecithin:cholesterol acyltransferase 3.1
alanine aminotransferase 3.1
tissue kallikrein 3.1
alkaline phosphatase 3.0
hexokinase 3.0
MDP 3.0
adenylate cyclase 2.9
phosphoenolpyruvate carboxykinase 2.9
phosphoenolpyruvate carboxykinase 2.9
creatine kinase 2.8
transpeptidase 2.8
AST 2.8
phosphoenolpyruvate carboxykinase 2.7
leucine aminopeptidase 2.7
lactate dehydrogenase 2.6
ornithine transcarbamylase 2.6
HSD 2.6
tryptophan hydroxylase 2.6
prolyl hydroxylase 2.5
ATPase 2.5
glucose-6-phosphate dehydrogenase 2.4
DCF 2.4
phosphodiesterase 2.3
alpha-glucosidase 2.3
glutamate decarboxylase 2.3
chaperonin 2.3
PDK1 2.2
GSK 2.2
NOS 2.1
CD10 2.1
NO synthase 2.0
BMT 2.0
phosphorylase 1.9
5'-nucleotidase 1.7
CPT 1.7
furin 1.7
calcineurin 1.6
CPT 1.6
MAP 1.5
arginase 1.5
carbonic anhydrase 1.5
more...
Compound
2-Bromoethylamine hydrobromide 10.8
2-Bromoethylamine hydrobromide 10.8
N-isopropylacetamide 10.5
Cortivazol 10.2
Lys-vasopressin 9.4
Dihydrotachysterol 9.1
TMTU 9.0
difluoroacetic acid 8.8
DTMA 8.5
Fludrocortisone 8.5
Phosphate ion 8.5
Desmopressin 8.4
Swertiamarin 8.3
Merbarone 8.3
Niguldipine 8.1
Hydroxylysine 7.6
Lithium 7.5
Benzamil 7.5
Fructosamine 7.5
Sodium saccharin 7.4
NDPS 7.2
2-aminoethyl diphenylborinate 7.1
2-aminoethyl diphenylborinate 7.1
Vasopressin 7.1
Methoxyflurane 7.0
Umbelliferone 6.8
o,p'-DDD 6.7
Chlorpropamide 6.7
4-Methylpyrazole 6.6
Paricalcitol 6.6
Foscarnet 6.6
Diamminedichloroplatinum 6.5
Inulin 6.4
SHM 6.3
hexyl acetate 6.3
CD 3 6.3
Polydatin 6.2
Sorbinil 6.2
STZ 6.2
Tropisetron 6.2
Glimepiride 6.1
MeCCNU 6.1
DCVC 6.1
Lupeol 6.1
Gatifloxacin 5.9
VO4 5.9
1,2-ethanediamine 5.8
P 2 5.8
Acarbose 5.8
alcohol dehydrogenase 5.8
Mercury, 5.7
Mercury, 5.7
Mercury, 5.7
Mercury, 5.7
Mercury, 5.7
Thiazide 5.7
Mercury, 5.7
Mercury, 5.7
Zonisamide 5.7
aldosterone 5.7
Aristolochic acid 5.7
Actinomycin 5.6
creatinine 5.6
Diallyl 5.6
Triamcinolone acetonide 5.5
Indomethacin 5.5
Nisoldipine 5.4
alloxan 5.4
Ifosfamide 5.3
Mirtazapine 5.3
Irbesartan 5.2
Dexmedetomidine 5.2
Prednisolone 5.1
PGA2 5.1
Enalapril 5.1
Enflurane 5.1
Amiloride 5.1
Thiabendazole 5.1
Melamine 5.0
Hydrochlorothiazide 5.0
more...