Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0032463 (polycythemia vera)
3,374 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
JAK2 719
erythroid 324
Jak2 309
erythropoietin 280
Sep 227
hemoglobin 203
interferon 162
MPL 152
Calreticulin 105
tyrosine kinase 104
cytokine 98
Janus kinase 2 93
STAT 90
BCR 80
megakaryocyte 78
ABL 73
Mol 73
JAK1 70
BCR-ABL1 60
Janus kinase 56
lymphoid 54
CD34 54
IFN 54
granulocyte 47
TET2 46
thrombopoietin 44
alkaline phosphatase 42
MPN 42
interferon alpha 40
CML 40
cell surface receptor 39
ASXL1 39
She 38
thrombopoietin receptor 38
glycoprotein 37
STAT5 37
calreticulin 36
collagen 34
p53 34
interferon-alpha 31
thrombin 28
BCR/ABL 26
erythropoietin receptor 24
bcr 22
Pol 22
mast cell 21
PMS 21
Erythropoietin 20
IDH1 20
EZH2 20
von Willebrand factor 20
MPD 19
prothrombin 18
AML 18
histone deacetylase 17
MDS 17
non-Hodgkin's lymphoma 17
HES 17
KIT 16
fibrinogen 16
EPO 16
CBL 16
PDGFRA 15
IL-3 15
reserved 14
ferritin 14
IDH2 14
vascular endothelial growth factor 13
EPOR 13
X-chromosome 13
PDGFRB 13
thrombomodulin 13
lactate dehydrogenase 13
glucose-6-phosphate dehydrogenase 13
ATP 12
beta-thromboglobulin 12
TEL 12
DNMT3A 12
stem cell factor 12
HLA 12
more...
Disease
polycythemia vera 3374
essential thrombocythemia 1254
myeloproliferative disorders 825
primary myelofibrosis 742
myelofibrosis 638
cancer 463
chronic myeloid leukemia 417
thrombocytosis 337
leukemia 295
erythrocytosis 245
acute myeloid leukemia 214
polycythemia 177
myelodysplastic syndrome 175
anemia 159
acute leukemia 156
tumor 149
chronic myeloproliferative disorders 147
lymphoma 133
thrombocytopenia 94
multiple myeloma 92
Leukemia 78
pruritus 78
secondary polycythemia 77
ABL 73
Budd-Chiari syndrome 70
hypertension 54
HHT 50
chronic lymphocytic leukemia 50
Hodgkin's disease 47
chronic myelomonocytic leukemia 46
blast crisis 45
hematologic malignancies 41
mastocytosis 39
Mitchell 39
stroke 39
secondary myelofibrosis 37
chronic lymphocytic leukemia 36
erythroleukemia 36
chronic neutrophilic leukemia 34
myocardial infarction 34
acute lymphoblastic leukemia 34
Aujeszky's disease 32
myeloid leukemia 31
aplastic anemia 30
portal hypertension 29
myelosuppression 28
Thrombus 27
chronic eosinophilic leukemia 26
thalassemia 24
sickle cell disease 24
dysplasia 24
diabetes 23
iron deficiency 23
ischemia 22
refractory anemia 22
rheumatoid arthritis 21
Best 19
cirrhosis 19
non-Hodgkin's lymphoma 18
pancytopenia 18
paroxysmal nocturnal hemoglobinuria 17
lymphoblastic leukemia 17
eosinophilia 17
MDS 17
osteomyelofibrosis 16
telangiectasia 16
renal failure 15
cerebral infarction 15
trisomy 8 15
acute nonlymphocytic leukemia 15
iron deficiency anemia 15
pulmonary embolism 15
HIV 15
thrombocytopenic purpura 15
carcinoma 15
panmyelosis 14
trisomy 14
plaque 14
vascular disease 14
depression 14
more...
Symptom
splenomegaly 270
pain 46
fatigue 44
headache 41
abdominal pain 31
hepatomegaly 21
hepatosplenomegaly 20
diarrhea 18
dizziness 17
chorea 17
nausea 12
anorexia 11
dyspnea 11
anesthesia 10
vomiting 10
night sweats 9
weakness 7
discomfort 7
bone pain 7
paresthesia 6
erythema 6
discomfort 6
vertigo 6
paraparesis 6
numbness 5
seizures 5
chest pain 5
nausea and vomiting 4
cyanosis 4
intestinal bleeding 4
Ill 4
angina 4
cough 3
clubbing 3
asthenia 3
insomnia 3
back pain 3
acute abdomen 3
abdominal discomfort 3
cachexia 3
arthralgia 2
syncope 2
sleepiness 2
tremor 2
blurred vision 2
regurgitation 2
ataxia 2
dry skin 2
lightheadedness 2
decreased appetite 2
functional recovery 2
ophthalmoplegia 2
hemoptysis 2
hemiplegia 2
paresis 2
myalgia 2
analgesia 2
tingling 2
polyuria 1
chronic cough 1
tachypnea 1
Amaurosis fugax 1
acidity 1
right upper quadrant pain 1
memory loss 1
respiratory distress 1
disturbed balance 1
lumbar back pain 1
dry eye 1
shoulder pain 1
finger pain 1
livedo 1
Severe pain 1
atypical chest pain 1
sneezing 1
asynergy 1
shortness of breath 1
arm pain 1
wheezing 1
spasm 1
more...
Drug
Dermatol 35
Cardiovasc 19
MDS 17
Anagrelide 16
CSF 11
Imatinib 10
PTH 7
TEL 6
G-CSF 6
IL-2 5
Gleevec 5
VCR 4
IFN-gamma 4
nitroglycerin 4
Nephron 4
IL-11 3
caffeine 3
LCM 3
Leaf 3
Nephron 3
LCM 3
Coumadin 2
MAP 2
SMP 2
Vitamin B12 2
ROC 2
Erlotinib 2
CTX 2
Lenalidomide 2
Hypaque 2
NADH 2
MRC 2
Hypaque 2
Pegasys 2
PPA 2
Monit 2
Palmitoyl 2
Portal 2
Digitalis 1
RFP 1
Vitamin K 1
ALA 1
AMC 1
Interferon alfa-2a 1
pyridoxal phosphate 1
Diamminedichloroplatinum 1
Norplant 1
Mutagen 1
Vorinostat 1
Asn 1
Prednisone 1
Paraffin 1
Adenosine deaminase 1
Check 1
Aprotinin 1
Glide 1
Orphan 1
Ranimustine 1
Fluorescein 1
ENT 1
Madopar 1
Ringer's solution 1
Argatroban 1
Clopidogrel 1
Gastro 1
Doxycycline 1
Fondaparinux 1
Glutathione 1
DDAVP 1
DDAVP 1
ETS 1
Rituximab 1
Tarceva 1
Fluorescein 1
Acitretin 1
vitamin E 1
Antithrombin III 1
PMEA 1
DOXY 1
Adriamycin 1
more...
Enzyme
focal adhesion kinase 834
ERK 56
alkaline phosphatase 42
thrombin 27
peroxidase 20
APC 17
mitogen-activated protein kinase 17
lactate dehydrogenase 15
reverse transcriptase 14
glucose-6-phosphate dehydrogenase 14
protein kinase 10
thromboplastin 8
tissue plasminogen activator 7
RNase 6
alanine aminotransferase 6
aspartate aminotransferase 6
RNase 6
ribonucleotide reductase 5
DNA polymerase 5
tryptase 5
catalase 5
protein kinase C 4
thymidine kinase 4
acetylcholinesterase 4
ribonucleotide reductase 4
plasmin 4
farnesyltransferase 3
farnesyltransferase 3
lysozyme 3
superoxide dismutase 3
RNA polymerase 3
beta-galactosidase 3
luciferase 3
NOS 3
thyroid peroxidase 3
transcriptase 3
trypsin 3
choline acetyltransferase 3
PRA 3
ribonuclease 3
glutathione reductase 3
phosphoglycerate kinase 3
CD13 3
ribonuclease 3
DNA methyltransferase 3
neutrophil elastase 2
gamma-glutamyl transpeptidase 2
CYP3A4 2
PGM 2
caspase-3 2
ACS 2
lipoxygenase 2
NQO1 2
methylenetetrahydrofolate reductase 2
calcineurin 2
MEK 2
glyceraldehyde-3-phosphate dehydrogenase 2
methylenetetrahydrofolate reductase 2
cholinesterase 2
ATPase 2
MAP 2
acid phosphatase 2
MIP 2
glutathione peroxidase 2
MMP-3 2
phosphofructokinase 2
endoglycosidase H 2
neuraminidase 2
PARP 2
CD10 2
proteasome 2
endonuclease 2
urokinase-type plasminogen activator 2
phosphodiesterase 2
ACE 2
SMP 2
renin 2
p-nitrophenylphosphatase 1
kallikrein 1
elastase 1
more...
Compound
Clin 268
Dec 200
DNA 164
BCR 80
oxygen 75
ABL 73
iron 66
tyrosine 49
Hydroxyurea 47
phosphorus 39
ASA 23
Phe 18
calcium 17
His 17
ADP 16
Hemoglobin 14
sodium 13
Cardiol 13
urea 13
water 13
Busulfan 13
ATP 12
nitric oxide 11
valine 11
glucose 10
ADP 10
ADP 10
creatinine 10
acetate 9
phosphate 9
serine 9
threonine 9
SET 8
MCNU 8
arginine 7
PEG 7
leucine 7
PEG 7
TEL 6
zinc 6
CO2 6
cysteine 6
SDS 6
PAS 5
Thrombin 5
methionine 4
glutamate 4
nitrogen 4
TNF 4
DPG 4
LCR 4
EDTA 4
GABA 4
DPG 4
GABA 4
Pipobroman 4
sulfate 4
EDTA 4
T10 4
MEP 3
A 42 3
T11 3
Ara-C 3
GSH 3
glycerol 3
NADPH 3
Ile 3
AMP 3
TEM 3
Asp 3
aspartic acid 3
MDA 3
lysine 3
hydroxide 3
retinoic acid 3
Warfarin 3
alanine 3
ethanol 3
boron 3
PGE2 3
more...