Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0032463 (polycythemia vera)
 3,374 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MPD6 13.2
KIAA0355 11.6
CMPD 11.2
Jak2 11.1
MPL 10.6
BCAM 10.5
EIF4F 10.4
JAK2 10.3
Calreticulin 10.1
GPX8 9.9
CD177 9.8
laminin alpha 5 9.7
Janus kinase 2 9.7
CBF-beta 9.6
CARD6 9.6
Lutheran glycoprotein 9.5
JAK2 protein 9.5
BCR/ABL1 fusion 9.5
SOX30 9.4
FOXD4 9.4
MS4A3 9.4
EPOR 9.4
janus kinase 2 9.3
Lutheran blood group 9.3
ASXL1 9.3
thrombopoietin receptor 9.3
KANK 9.2
SSBP2 9.2
AML1/MDS1 9.1
PDE4DIP 9.0
CORO1A 9.0
DEFA4 9.0
BCR-ABL1 8.9
ICAM-4 8.8
KI1 8.8
JAK-2 8.8
Lnk 8.8
TET2 8.8
U2AF1 8.7
MPD 8.7
c-MPL 8.7
bone morphogenetic protein 8B 8.6
JAK1 8.6
SH2B3 8.5
MPN 8.5
TIMAP 8.4
MLLT3 8.4
HBS1L 8.4
RPN1 8.4
UBE2H 8.4
MFRP 8.3
PTPRR 8.3
ALG2 8.3
TNFRSF19 8.3
PDGFRB 8.3
tyrosine kinase 2 8.2
BRD4 protein 8.2
MNDA 8.2
GNAI2 8.0
IL1RAP 8.0
erythropoietin receptor 8.0
CRV 8.0
myeloid leukemia factor 1 8.0
runt-related transcription factor 1 8.0
Epo receptor 7.9
colony stimulating factor receptor 7.9
BCR/ABL 7.9
ELN 7.8
CEL 7.8
RCOR1 7.8
JMJD2C 7.8
ARPP-19 7.8
basal cell adhesion molecule 7.7
GAS2 7.7
L3MBTL1 7.7
BCORL1 7.7
Janus kinase 1 7.7
MPP1 7.7
CBL 7.6
HES 7.6
UT2 7.6
Janus kinase 7.6
TC II 7.6
megakaryocyte 7.5
GBP2 7.5
ZRSR2 7.5
carcinoembryonic antigen-related cell adhesion molecule 7.5
SLC14A1 7.5
cystatin F 7.5
JMJD1C 7.5
erythropoietin 7.5
CALC 7.4
ZNF198 7.4
MEG2 7.3
P72 7.3
BCR/ABL fusion 7.3
ABL 7.3
Poly(A) polymerase 7.3
P32 7.3
thrombopoietin 7.3
GFI1B 7.3
stem cell growth factor 7.3
HIF2A 7.3
retinoid X receptor beta 7.3
Protease-activated receptor 2 7.3
ABL1 7.3
SF3B1 7.3
mpo 7.3
THPO 7.3
IDH2 7.2
bcr 7.2
LIG3 7.2
IL1R 7.2
transcobalamin I 7.2
RBM15 7.2
ST6GAL1 7.2
erythroid 7.2
OBR 7.1
SELP 7.1
TNL 7.1
PRDX2 7.1
P12A 7.1
calreticulin 7.1
ABL2 7.1
granulocyte colony-stimulating factor receptor 7.1
JAK3 7.1
CD164 7.1
PMS 7.1
BCR-ABL fusion 7.1
CAP37 7.1
RECQL5 7.1
JARID2 7.0
SOCS-2 7.0
N-ras oncogene 7.0
BMP3 7.0
SMARCA2 7.0
neutrophil protein 7.0
EKLF 7.0
interferon alpha 6.9
SAV 6.9
BMP10 6.9
RAC2 6.9
Suppressor of cytokine signaling 1 6.9
bcr/abl 6.9
CAP2 6.9
PDGFRA 6.9
vav 6.9
BCR 6.9
CASP2 6.9
CML 6.9
CARD8 6.8
IDH1 6.8
KLF1 6.8
PCM1 6.8
ATOX1 6.7
CRABP2 6.7
PRDX6 6.7
NEU1 6.7
HDAC11 6.7
receptor protein-tyrosine kinase 6.7
more...
Disease
polycythemia vera 13.2
Acute erythremia 13.2
anemia; progressive 13.2
nephrorrhagia 13.2
Primary erythrocytosis 12.6
essential thrombocytopenia 12.3
essential thrombocythemia 12.2
Gaisbock's syndrome 12.2
CMPD-U 12.2
Aquagenic pruritus 11.9
panmyelosis 11.8
primary myelofibrosis 11.7
secondary myelofibrosis 11.7
Secondary erythromelalgia 11.6
hypercalcaemia due to parathyroid adenoma 11.6
MDS/MPD-U 11.6
chronic myeloproliferative disorders 11.5
secondary polycythemia 11.4
PFCP 11.2
osteomyelofibrosis 11.0
nonhematologic cancer 10.9
erythrocytosis 10.9
chronic neutrophilic leukemia 10.8
Relative polycythaemia 10.7
myelofibrosis 10.6
myeloproliferative disorders 10.6
chronic eosinophilic leukemia 10.6
Myeloproliferation 10.4
osteomyelosclerosis 10.4
CMD1 10.0
Toxoplasma retinitis 10.0
polycythemia 9.9
thrombocytosis 9.8
secondary myelodysplastic syndromes 9.6
Familial erythrocytosis 9.5
Cardiac embolism 9.4
trisomy 9 9.4
accelerated phase CML 9.3
sideroblastosis 9.3
MDS-U 9.2
Reactive thrombocytosis 9.2
Hepatic venous outflow obstruction 9.1
Ph- CML 9.0
Myeloid metaplasia 9.0
hypolipoproteinemia 9.0
CRV 8.9
Budd-Chiari syndrome 8.8
trisomy 1q 8.8
HHT 8.8
bone marrow disorder 8.6
Nutritional anemia 8.6
MDS/MPD 8.6
Nodular lymphoid hyperplasia 8.5
Pulmonary vein thrombosis 8.4
chronic myelomonocytic leukemia 8.3
Chloroma 8.3
atypical chronic myeloid leukemia 8.3
Aujeszky's disease 8.3
Philadelphia chromosome positive chronic myelogenous leukemia 8.2
malignant myeloma 8.1
leukoerythroblastosis 8.1
AML/MDS 8.0
Fletcher trait 8.0
Mitchell 8.0
acrocyanosis 7.9
FAB M2 7.8
chronic leukemia 7.8
chronic myeloid leukemia 7.7
acute alcoholism 7.7
Microangiopathic hemolytic anemia 7.6
refractory anemia 7.5
hyperviscosity syndrome 7.5
congenital amegakaryocytic thrombocytopenia 7.4
blast crisis 7.4
sideroblastic anemia 7.4
mastocytosis 7.4
megakaryocytic leukemia 7.4
acute leukemia 7.3
juvenile myelomonocytic leukemia 7.3
secondary AML 7.3
hereditary chorea 7.2
ABL 7.2
Rotavirus gastroenteritis 7.2
trisomy 8 7.2
Ventricular septal rupture 7.1
Aujeszky 7.0
HPCD 7.0
RARS 7.0
osteosclerosis 7.0
plasmacytosis 7.0
Leukemia cutis 6.9
blood cancer 6.9
BMH 6.9
Thrombus 6.9
Philadelphia chromosome positive 6.8
myelodysplastic syndrome 6.8
Stretches 6.8
Sydenham's chorea 6.8
splenic infarction 6.8
Clonal evolution 6.7
frontal lobe syndrome 6.7
paroxysmal nocturnal hemoglobinuria 6.7
Activated protein C resistance 6.6
vascular ischemia 6.6
Retinal vein occlusion 6.6
Dieulafoy lesion 6.6
acute nonlymphocytic leukemia 6.6
GIN 6.6
blood disorder 6.6
abulia 6.6
Reinke's edema 6.5
HES 6.5
thalassemia minor 6.4
RAEB 6.4
erythroleukemia 6.4
Monoclonal gammopathy 6.3
Factor V Leiden mutation 6.3
cerebral thrombosis 6.2
xerosis 6.2
myeloid leukemia 6.2
Glanzmann 6.1
Eosinophilic fasciitis 6.1
hypertropia 6.1
generalized tuberculosis 6.1
lichen simplex chronicus 6.1
MDS 6.1
HDL1 6.0
hemichorea 6.0
hepatic adenoma 6.0
simian AIDS 6.0
second cancer 6.0
kidney infection 6.0
dysproteinemia 5.9
FAB M4 5.9
pyoderma gangrenosum 5.9
neuronitis 5.9
idiopathic disorder 5.9
acute myeloid leukemia 5.8
telangiectasia 5.8
splenitis 5.8
Coats' disease 5.8
coronary thrombosis 5.8
mesenteric thrombosis 5.8
pyruvate kinase deficiency 5.8
Cerebral venous sinus thrombosis 5.8
mast cell leukemia 5.8
urticaria pigmentosa 5.7
Cavernous hemangioma 5.7
Focal nodular hyperplasia 5.7
EEC 5.7
chronic phase CML 5.7
pruritus 5.7
congenital immunodeficiency 5.6
Leukemia 5.6
TRPS1 5.6
aplastic anemia 5.6
myoblastoma 5.6
hematologic malignancies 5.6
acute undifferentiated leukemia 5.5
Spontaneous bacterial peritonitis 5.5
more...
Symptom
prickling sensation 9.3
splenomegaly 8.0
finger pain 8.0
Amaurosis fugax 7.6
lumbar back pain 6.8
chorea 6.3
night sweats 6.1
chromosome marker 6.1
Severe pain 5.9
intestinal bleeding 5.6
hepatosplenomegaly 5.4
disturbed balance 5.4
physical symptom 5.3
lightheadedness 5.2
hepatomegaly 5.1
clubbing 5.0
bone pain 4.4
paraparesis 4.4
stomach pain 4.2
arm pain 4.2
dry skin 4.2
ankle pain 4.1
dizziness 4.0
abdominal discomfort 4.0
decreased appetite 4.0
tingling 3.9
atypical chest pain 3.9
asynergy 3.9
forgetfulness 3.8
right upper quadrant pain 3.8
paresthesia 3.5
livedo 3.5
general problem 3.4
asthenia 3.4
cyanosis 3.3
abdominal pain 3.2
acute abdomen 3.2
numbness 3.2
blurred vision 3.2
hypoproteinemia 3.1
fatigue 3.0
vertigo 3.0
hot flushes 2.9
anorexia 2.9
headache 2.8
ophthalmoplegia 2.5
cachexia 2.3
sneezing 2.3
nausea 2.3
hemiplegia 2.2
chronic cough 2.2
leg pain 2.2
twitching 2.2
heartburn 2.2
erythema 2.1
polydipsia 2.1
stridor 2.0
nausea and vomiting 2.0
pallor 1.9
tachypnea 1.9
dyspnea 1.9
dry eye 1.8
shoulder pain 1.8
Ill 1.8
paresis 1.7
polyuria 1.6
hemoptysis 1.6
vomiting 1.6
diarrhea 1.6
myalgia 1.5
exertional dyspnea 1.5
chest pain 1.5
discomfort 1.4
insomnia 1.4
arthralgia 1.4
memory loss 1.4
discomfort 1.3
neck pain 1.3
back pain 1.2
regurgitation 1.2
chills 1.1
syncope 1.0
wheezing 1.0
shortness of breath 0.9
angina 0.8
ENT 0.8
weakness 0.8
pain 0.7
lethargy 0.7
hypotonia 0.7
flushing 0.6
sleepiness 0.6
functional recovery 0.5
spasm 0.4
ataxia 0.2
cough 0.2
tremor 0.0
constipation -0.1
anesthesia -0.2
agitation -0.4
analgesia -0.6
acidity -0.7
seizures -0.8
hypothermia -0.9
respiratory distress -1.1
collapse -1.6
Drug
Anagrelide 10.7
IHMS 10.4
Ranimustine 10.4
Thioguanine 8.2
Interferon alfa-2a 7.8
Pegasys 7.7
DOXY 7.5
Tipifarnib 7.1
Lepirudin 6.8
Madopar 6.4
TEL 6.2
MDS 6.2
LCM 6.0
Palmitoyl 6.0
LCM 6.0
Acitretin 6.0
Coumadin 5.8
SMP 5.6
Diamminedichloroplatinum 5.5
Tarceva 5.4
Argatroban 5.3
Imatinib 5.2
Bestatin 5.0
Gleevec 5.0
PPA 5.0
Fondaparinux 4.9
Lenalidomide 4.9
HPMPC 4.7
Vorinostat 4.7
IL-11 4.7
Erlotinib 4.7
VCR 4.6
Antithrombin III 4.2
Orphan 4.1
Hypaque 4.1
Digitalis 3.9
Hypaque 3.9
Vitamin B12 3.9
Glide 3.9
Adenosine deaminase 3.8
Tocopherol 3.8
Gelfoam 3.7
PMEA 3.7
G-CSF 3.4
Gastro 3.4
Aprotinin 3.4
DDAVP 3.3
PTH 3.3
NVP 3.3
DDAVP 3.3
Prednisone 3.2
Doxycycline 3.1
Clopidogrel 3.1
AMC 3.0
RFP 3.0
FeCl3 2.8
Vitamin K 2.7
MRC 2.5
PTC 2.4
Norplant 2.4
Check 2.2
Portal 2.2
Paraffin 2.1
nitroglycerin 2.1
Captopril 2.1
TAT 2.0
pyridoxal phosphate 1.9
ETS 1.8
Alliance 1.8
Fluorescein 1.8
ALA 1.7
CSF 1.7
Ringer's solution 1.7
Rituximab 1.7
Fluorescein 1.3
ROC 1.3
Nephron 1.2
PCB 1.2
Nephron 1.1
Adriamycin 1.0
CTX 0.9
Glutathione 0.8
Histamine 0.8
IL-2 0.7
Mutagen 0.7
caffeine 0.4
Leaf 0.4
IFN-gamma 0.4
Dermatol 0.3
MAP 0.3
ENT 0.1
Cardiovasc -0.2
NADH -0.2
Asn -0.3
Monit -0.9
vitamin E -0.9
ROS -1.0
Enzyme
focal adhesion kinase 7.5
enzyme X 7.3
arachidonate 5-lipoxygenase 6.0
phosphoglyceromutase 5.6
PHT 5.3
SMP 4.8
farnesyltransferase 4.8
nicotinamide phosphoribosyltransferase 4.7
lactic acid dehydrogenase 4.4
lactic acid dehydrogenase 4.3
cathepsin S 4.2
farnesyltransferase 4.2
Hageman factor 4.2
PRA 4.1
tryptase 4.1
glucose-6-phosphate dehydrogenase 4.1
ribonucleotide reductase 4.0
p-nitrophenylphosphatase 3.9
poly(A) polymerase 3.8
phosphatidylinositol 4-kinase 3.8
PGM 3.7
ribonucleotide reductase 3.7
phosphoglycerate kinase 3.7
lactic acid dehydrogenase 3.6
BAT 3.5
12-lipoxygenase 3.5
endoglycosidase H 3.4
histone demethylase 3.3
APC 3.3
nucleotidase 3.2
thyroid peroxidase 3.2
methylenetetrahydrofolate reductase 3.2
methylenetetrahydrofolate reductase 3.1
alkaline phosphatase 3.0
CD13 3.0
TSA 3.0
thrombin 2.9
dihydropyrimidine dehydrogenase 2.9
chymase 2.8
phosphoglucomutase 2.8
6-phosphogluconate dehydrogenase 2.7
6-phosphogluconate dehydrogenase 2.7
histidine decarboxylase 2.7
sialyltransferase 2.6
apyrase 2.6
sialyltransferase 2.6
sialyltransferase 2.6
tissue plasminogen activator 2.5
thromboplastin 2.5
DNA methyltransferase 2.5
DTA 2.5
PTA 2.5
ERK 2.5
MMP-3 2.5
cathepsin G 2.4
thymidine kinase 2.3
TdT 2.3
phosphofructokinase 2.3
lactate dehydrogenase 2.3
adenylate kinase 2.3
neutrophil elastase 2.2
choline acetyltransferase 2.2
ribonuclease 2.1
ribonuclease 2.1
plasmin 2.1
reverse transcriptase 2.1
TAT 2.0
NOS 2.0
MIP 1.9
hypoxanthine-guanine phosphoribosyltransferase 1.9
SPC 1.9
MDP 1.8
RNase 1.8
RNase H 1.8
diaphorase 1.8
RNase 1.7
carboxylesterase 1.7
protein phosphatase 2A 1.6
NQO1 1.6
isocitrate dehydrogenase 1.6
transcriptase 1.6
5'-nucleotidase 1.6
glutathione reductase 1.6
CYP3A4 1.6
glyceraldehyde-3-phosphate dehydrogenase 1.5
peroxidase 1.5
DNA polymerase 1.5
isocitrate dehydrogenase 1.5
aldolase 1.4
aspartate aminotransferase 1.4
S1 nuclease 1.4
PDE 1.4
MAP 1.3
enolase 1.3
arginase 1.3
phospholipase D 1.3
NADPH-diaphorase 1.3
lipoxygenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
PAH 1.1
alanine aminotransferase 1.1
gamma-glutamyl transpeptidase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.0
beta-galactosidase 1.0
CD10 0.9
glutamine synthetase 0.9
ceruloplasmin 0.9
chloramphenicol acetyltransferase 0.9
pyruvate kinase 0.9
alpha-amylase 0.8
hexokinase 0.8
urokinase-type plasminogen activator 0.8
glyceraldehyde-3-phosphate dehydrogenase 0.7
mitogen-activated protein kinase 0.7
phosphoinositide 3-kinase 0.7
diaphorase 0.7
kallikrein 0.6
AST 0.6
cholinesterase 0.6
ornithine decarboxylase 0.6
acid phosphatase 0.6
PARP 0.5
lipoprotein lipase 0.4
acetylcholinesterase 0.4
lysozyme 0.4
neuraminidase 0.4
protein kinase 0.2
cdc2 0.2
calcineurin 0.1
tyrosinase 0.1
MEK 0.1
elastase 0.1
ACE 0.0
topoisomerase 0.0
endonuclease 0.0
phosphodiesterase 0.0
topoisomerase -0.1
glutathione peroxidase -0.2
phosphatidylinositol 3-kinase -0.2
catalase -0.2
RNA polymerase -0.3
protein kinase C -0.4
luciferase -0.4
beta-lactamase -0.5
trypsin -0.6
phospholipase A2 -0.6
proteasome -0.6
tyrosine hydroxylase -0.6
NO synthase -0.7
caspase-3 -0.9
renin -0.9
collagenase -1.0
phospholipase C -1.0
creatine kinase -1.0
adenylate cyclase -1.0
superoxide dismutase -1.1
glutathione S-transferase -1.3
ATPase -1.8
ACS -2.1
more...
Compound
Pipobroman 12.2
AD-143 12.2
Uracil mustard 10.9
Chlormerodrin 9.9
Thione 9.4
BQA 9.4
MCNU 9.2
Pyrazofurin 8.9
Interferon alfa-2a 8.8
Hydroxyurea 8.6
Carboquone 8.2
Reticulin 8.0
Busulfan 7.9
Carboquone 7.8
Carboquone 7.8
Carboquone 7.8
Carboquone 7.8
Aminopterin 7.6
Echinomycin 7.3
BCR 6.9
ABL 6.9
HM-3 6.7
D 3 6.7
Chlorambucil 6.6
Phenylhydrazine 6.6
NIX 6.4
TEL 6.2
6-Thioguanine 6.2
Fibrinopeptide A 6.1
Tirofiban 6.1
Benzidine 6.0
PIH 5.8
Prone 5.6
LCR 5.5
Argatroban 5.4
PHT 5.2
Pamidronate 5.1
SET 5.1
CMK 5.0
MBH 5.0
merocyanine 540 5.0
Psoralen 4.9
DPG 4.9
Oxacillin 4.9
Pyrimethamine 4.9
TET 4.9
TET 4.9
Bestatin 4.8
MEP 4.8
PPA 4.8
DBM 4.7
DBM 4.7
MEP 4.7
NMA 4.6
DEK 4.6
SSD 4.6
5-Azacytidine 4.4
2,3-diphosphoglycerate 4.4
HCP 4.4
DPG 4.4
Nodular 4.3
Bordeaux 4.3
Azathioprine 4.2
Hemoglobin 4.2
Ara-C 4.2
HCP 4.1
dGMP 4.1
5-HETE 4.0
T13 4.0
NMP 4.0
T10 4.0
T11 4.0
Etanercept 3.9
MAK 3.9
Amlodipine 3.9
Hypaque 3.9
MBT 3.9
PPA 3.8
ASA 3.8
Ara-C 3.8
TXA2 3.7
DMP 3.7
ATC 3.7
HBB 3.7
DMP 3.7
DMP 3.6
ATC 3.6
L-PAM 3.6
ethyl carbamate 3.6
MPC 3.6
L-PAM 3.6
LTE4 3.6
2-methylpiperazine 3.6
CPB 3.5
Thrombin 3.5
HPC 3.4
AAT 3.4
Warfarin 3.4
HPC 3.4
CCNU 3.4
Vincristine 3.4
Glutaraldehyde 3.3
PGD2 3.3
CMP 3.3
A 42 3.3
Imipramine 3.3
Imipramine 3.3
Naltrexone 3.2
CMP 3.2
Fibrin 3.1
methylhistamine 3.1
Staurosporine 3.1
Sialic acid 3.1
Dipyridamole 3.1
Dipyridamole 3.1
Dipyridamole 3.1
Dipyridamole 3.1
Rose Bengal 3.0
Staurosporine 3.0
phosphorus 3.0
Vitamin K 3.0
GPT 3.0
PAS 2.9
Tyrosine 2.9
valine 2.8
TTP 2.8
CNQX 2.7
dCTP 2.7
TMA 2.6
TMA 2.6
MCA 2.6
Amide 2.6
MCA 2.6
Histone 2.5
Prednisone 2.5
CCP 2.5
Neo 2.5
glucose-6-phosphate 2.4
C2H2 2.4
DTA 2.4
quinazoline 2.4
quinazoline 2.4
Proline 2.4
DMP 2.3
ATF 2.3
SPM 2.3
tyrosine 2.3
Reserpine 2.2
Agar 2.2
TCM 2.2
TCM 2.2
iron 2.2
A 71 2.1
MMA 2.0
PNA 1.9
Thromboxane 1.9
phosphoserine 1.9
Hematoxylin 1.9
TBI 1.8
DIC 1.8
more...