Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0032463 (
polycythemia vera
)
3,374
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The aim of our study was to evaluate the possible effect of
lipocalin 2
on thrombotic events in
polycythemia vera
and essential thrombocythemia patients. The samples of 89 patients were collected and RNA based method was used to evaluate the relative gene expression level of
lipocalin 2
. 74 samples were available for evaluation. Drawing a cut off point at level 30 relative expression rate, 13 patients with elevated
lipocalin 2
expression had thrombotic events during the course of their disease. Based on these data high
lipocalin 2
expression level seems to have strong positive predictive value on thrombotic events in patients with
polycythemia vera
and essential thrombocythemia. Lipocalin 2 may be useful in thrombotic risk stratification in these patients.
...
PMID:Increased Lipocalin 2 level may have important role in thrombotic events in patients with polycythemia vera and essential thrombocythemia. 2716 23
