Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0032463 (polycythemia vera)
 3,374 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An 87-year-old male patient known to have polycythemia vera presented at the hospital as an acute abdominal emergency. Ultrasonography of the abdomen revealed a homogeneous echogenic mass measuring 22 X 15 X 8 cm in fascial planes anterior to the peritoneum, which was consistent with a hematoma. His platelet count was 937,000/mm3. The patient responded to plateletpheresis and supportive management. Older patients with polycythemia vera may present as acute abdomen secondary to spontaneous abdominal wall hematoma. Computerized tomography or ultrasonography of the abdomen can aid in making the diagnosis and preventing unnecessary surgical intervention.
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PMID:Spontaneous massive abdominal wall hematoma in polycythemia vera. 643 15

Bleeding is a common complication of such myeloproliferative disorders as polycythemia vera, and it usually occurs in either the skin or mucosa. We experienced a case of a massive retroperitoneal hematoma with no history of trauma in association with polycythemia vera. A 68-year-old man was referred to our hospital as a case of acute abdomen, and was diagnosed as having a retroperitoneal hematoma and polycythemia vera based on radiological and hematological examinations. Because the mass effect of the hematoma caused a progressive deterioration of his respiratory condition, surgical drainage was necessitated and successfully undertaken. Although conservative treatment is reportedly sufficient and uncontrollable intraoperative bleeding may occur, especially in cases of myeloproliferative disorders, our experience suggests that an operation may nevertheless be occasionally advisable for this rare condition.
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PMID:Successful surgical treatment for spontaneous retroperitoneal hematoma in polycythemia vera: report of a case. 1066 50

A 54-year-old woman with polycythemia vera (PV) presented as an emergency patient with acute abdomen. Her platelet count was 119 x 10(4)/microl. Computed tomography scan revealed fluid accumulation in the omentum and peritoneal space. An emergency laparotomy was undertaken because of severe abdominal pain and omental bleeding was diagnosed. Peritoneal hemorrhage and hematoma weighing in total 1040 g was drained. Although a part of the omentum and stomach was excised, we could not find any orifice from which bleeding could have occurred despite a thorough pathological examination. Massive hemorrhage should be considered in cases with PV presenting as acute abdomen, especially when the platelet count is extremely high (over 100 x 10(4)/microl).
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PMID:[Spontaneous omental bleeding presenting as acute abdomen during treatment for polycythemia vera]. 1644 8