Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0032290 (aspiration pneumonia)
 2,291 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anatomical and functional changes of the oral cavity, pharynx and larynx due to malignant tumor surgery and irradiation, cause breathing, swallowing, phonation and lung protection disorders. Deglutition disorders and choking are observed in all patients who have undergone supracricoid laryngectomy. We presented 33 patients after supracricoid laryngectomy with simultaneous CHEP (6) or CHP (27) reconstructions. 18 patients had one arytenoid cartilage removed, in 1 patient both of them were removed. Removal of the stomach tube took place between 29-36th day after the surgery. 4 patients showed symptoms of the aspiration pneumonia. Difficulties in swallowing liquids persist in some cases even a few years after the surgery. Re-education and rehabilitation of swallowing is the predominant problem and the most important goal after the CHP and CHEP surgery.
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PMID:[Swallowing disorders in patients after the laryngeal cancer surgery]. 764 94

The authors present a retrospective study of 463 partial horizontal laryngectomy of various types (horizontal supraglottic laryngectomy and its modifications, supracricoid laryngectomy with CHP and CHEP, glottic laryngectomy) performed in the years 1970-1991 in the ENT Clinic of Pomeranian Medical Academy in Szczecin. The aspiration pneumonia in 46 (about 10%) patients was observed as a result of insufficient lower airway protection. In cases of extended supraglottic laryngectomy (including the removal of one arytenoid cartilage and/or one vocal cord) aspiration pneumonia appeared more often (16%) than after classic supraglottic laryngectomy (6%). Reconstruction of elevation of arytenoid cartilage and/or vocal cord and base of tongue its extended resection augmented the efficacy lower airway protection.
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PMID:[Aspiration pneumonia following various types of partial horizontal laryngectomy]. 797 Jul 56