Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0032290 (aspiration pneumonia)
 2,291 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Between 1968 and 1978, 26 patients with carcinomas of the thoracic esophagus and 4 with adenocarcinomas involving the esophagogastric junction were treated by the insertion of indwelling intraluminal (endoesophageal) tubes. Four different types of tube were inserted by the pull-through technique. Thirteen of the 30 patients died in the hospital within 30 days. However, among the 20 patients who did not have neoplasms of the upper third of the thoracic esophagus or who had not had a prior resection, only 5 died. The principal cause of death was aspiration pneumonia. Survival averaged 2.5 months. Four patients survived 5 to 7 months. Deglutition was adequate in most patients but was not as satisfactory as after esophagogastrectomy. Our best results were obtained in patients with carcinoma of the middle or lower third of the esophagus, with or without an esophagorespiratory fistula, who had not had a previous resection.
Ann Thorac Surg 1979 Sep
PMID:Palliation of esophageal carcinoma with intraluminal tubes: experience with 30 patients. 9 Apr 89

Myotonic dystrophy or Steinert's disease may be discovered during acute respiratory failure, sometimes caused by a general anaesthetic. It complicates chronic respiratory failure which is present in almost all cases, both restrictive and obstructive, the clinical signs of which progress with the myopathy. Apart from myotonic degeneration of the respiratory muscles, a hypoventilation syndrome of central origin has been described, but the etiology of this respiratory failure is dominated by repeated aspiration pneumonia favoured by constant dysphagia and passage of food into the trachea and poor cough reflex. One should attempt to correct this.
Sem Hop 1977 Sep
PMID:[Myotonic dystrophy and acute respiratory insufficiency]. 19 96

In a patient with acute respiratory failure due to aspiration pneumonia, PaO2 decrease and Qs/Qt increase were observed during continuous positive pressure ventilation. This paradoxical finding was attributted to vascular collapse in well ventilated upper alveoli associated with blood flow redistribution to dependent hypoventilated areas with low ventilation-perfusion relationships.
Eur J Intensive Care Med 1976 Sep
PMID:Unusual response to continuous positive pressure ventilation. 78 39

A patient with a mobile mass of anaerobic organisms in the pulmonary parenchyma is presented. Radiographically it resembled a fungous ball. This observed botryomycoma may be part of the spectrum of aspiration pneumonia.
Chest 1976 Sep
PMID:Pulmonary botryomycoma. 95 67

The postmortem study of a classic case of Werner's syndrome is presented. The subject was a Japanese man who died at the age of 39. Major findings included general microsplanchnia, extreme atrophy of the testes and skin, calcified aortic atherosclerosis, an increase of basophils in the pituitary, aspiration pneumonia, chronic pyelonephritis and a meningioma in the occipital area of the brain. Histologically, no osteoporosis was evident in the lumbar spine and iliac bone. The findings suggest that in Werner's syndrome the dominant pathologic factor may be found in connective tissue other than bone.
J Am Geriatr Soc 1976 Sep
PMID:Postmortem study of a case of Werner's syndrome. 95 86

Three patients with anaerobic mediastinitis associated with retropharyngeal abscess have been encountered recently. Dental infections accounted for two instances, and the third instance resulted from rupture of the thoracic esophagus from blunt trauma. Each was marked by extreme difficulty in achieving complete abscess drainage due to the initially unrecognized virulence of the causative anaerobic bacteria. Complications were frequent and included empyema, pericarditis and aspiration pneumonia. The combination of vigorous diagnostic efforts, prompt operation and reoperation when necessary plus specific antibiotic effective against anaerobes led to a successful outcome for each patient.
Surg Gynecol Obstet 1976 Sep
PMID:Anaerobic mediastinitis. 95 54

Cardiopulmonary abnormalities are frequently encountered in myotonic dystrophy. We present five patients with myotonic dystrophy who entered the intensive care unit in acute respiratory failure. The possible etiologic factors of pulmonary complications are reviewed. The most important is probably aspiration pneumonia. The difficulties in the treatment of the respiratory failure are emphasezed. Myotonia of the chest muscles and diaphragm make artificial ventilation difficult. Recovery is delayed chiefly by swallowing disturbances. General anaesthesia is hazardous. Four patients presented cardiac arrhythmias and/or conduction abnormalities which were transient.
Eur J Intensive Care Med 1976 Sep
PMID:Respiratory failure and cardiac disturbances in myotonic dystrophy. 96 70

A patient receiving intravenous alcohol for premature labor developed mild aspiration pneumonia. In the course of her evaluation it was noted that she also had severe lactic acidosis. The patient responded well to hydration and intravenous sodium bicarbonate. Lactic acidosis represents a previously unrecognized danger of intravenous alcohol therapy.
Obstet Gynecol 1976 Sep
PMID:Severe lactic acidosis associated with intravenous alcohol for premature labor. 98 36

Some elderly patients with chronic illness such as stroke, or Parkinsonism cannot take food orally because of dysphagia. In such cases, tube feeding can be used as a supplement to oral intake when malnutrition is present. This route allows for easier nursing care and decreases the frequency of aspiration pneumonia. Complications of tube feeding include nutrient deficiency states, pulmonary aspiration, gastrointestinal and metabolic disorders. We report two cases with complications of acute gastric ulcer which was thought to be induced with long-term tube feeding. Case 1 was a 61-year-old male patient with Parkinson's disease for ten years. L-DOPA had been administered with good control of his condition. However, his ability to swallow has deteriorated gradually. As he often suffered from aspiration pneumonia, nasogastric tube feeding was performed. After three years of tube feeding, he suddenly vomited much bloody material. He died from massive bleeding with acute gastric dilatation. Autopsy showed giant acute gastric ulcer covered with coagulated blood. UL3, 50 mm in maximum diameter, was observed in the middle portion of the greater curvature, where the top of tube probably came in contact with the gastric wall. Case 2 was an 83-year-old female patient with stroke and chronic heart failure. She had been hospitalized for about one year because of the intermittent deterioration of her cardiac condition. Furthermore, her inability to swallow increased during her hospitalization. She also suffered from aspiration pneumonia. Nasogastric tube feeding was performed to prevent aspiration pneumonia and malnutrition. She died of acute heart failure after twelve months. Autopsy revealed heart dilatation, old myocardial infarction and stroke. In addition, two acute gastric ulcers (UL3.10 and 30 mm in diameter) were recognized; one was in the upper portion of the greater curvature, the other in the lower portion of the greater curvature. The location of these gastric ulcers was unusual. Moreover, they coincided with location of top of the nasogastric tube. From these two cases, we conclude that in long-term tube feeding the tip of the tube often comes in contact with the gastric wall, and gastric ulcer could be produced by repeated mechanical stimulus of the wall. Reports of acute gastric ulcer induced by tube feeding have not been published previously. Therefore, we should pay much attention to this complication in the care of the elderly people with long-term tube feeding.
Nihon Ronen Igakkai Zasshi 1992 Sep
PMID:[Long-term nasogastric feeding and complications of acute gastric ulcer in two elderly patients]. 143 62

The purpose of our study was to reanalyze the Depressive Experiences Questionnaire (DEQ; Blatt, D'Afflitti, & Quinlan, 1976, 1979) and to evaluate relationships between the questionnaire's factors and other construct-related measures, the Beck Depression Inventory (Beck, Ward, Mendelson, Mock, & Erbaugh, 1961) and the Edwards Personal Preference Schedule (Edwards, 1959). We argue that composite scores derived from this study's principal components analysis are more interpretively useful than the original factor scales reported by Blatt et al. (1976; Blatt, Quinlan, Chevron, McDonald, & Zuroff, 1982). Correlational evidence reported in this study does not support the Dependency and Self-Criticism factors as adequate representations of anaclitic and introjective depression (Blatt, 1974). The third DEQ factor scale, Efficacy, as revised for this study, demonstrated moderate to strong associations with other personality measures.
J Psychol 1992 Sep
PMID:Subtypes of depression, efficacy, and the Depressive Experiences Questionnaire. 149 63


1 2 3 4 5 6 7 8 9 10 Next >>