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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three hundred seventy-two cases of hospital-acquired pneumonia occurring during a 4-year period were reviewed. It was found that the annual incidence of the pneumonia was 1.44% which ranked first in the incidence of nosocomial infections at this institution. Most of the patients had suffered from primary severe underlying diseases with immunosuppression of different degrees. A variety of factors such as antibiotic and steroid therapy, operation, intensive care, endotracheal intubation, tracheostomy, chemotherapy and radiotherapy predisposed to the acquisition of this pneumonia. Most frequent etiologic agents for hospital-acquired pneumonia were Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans. The overall mortality rate was 25.3%. However, deaths associated with Pseudomonas aeruginosa and Staphylococcus aureus are particularly high, with rates of 70.6% and 66.7% respectively. The incidence, mortality, pathogenesis, diagnosis, treatment and prevention of the disorder were discussed briefly.
Zhonghua Nei Ke Za Zhi 1992 Jun
PMID:[Nosocomial pneumonia: a report of 372 cases]. 128 82

The resistance to antibiotics of the 985 clinical isolates collected in Tian Tan hospital was studied. The results showed that S. aureus had a resistant rate of more than 90% to penicillin and was also highly resistant to erythromycin. Methicillin resistant Staphylococcus Aureus (MRSA) was isolated in 15.6% of all the isolates with S. aureus. The isolation rate of MRSA is lower than that in other countries or districts of West Pacific Area. K. pneumonia and other Gram negative bacilli had a resistant rate of 0.6% to amikacin and P. aeruginosa was all sensitive to Polymyxin-B.
Zhonghua Nei Ke Za Zhi 1992 Sep
PMID:[Resistant rate to antibiotics in Tian Tan Hospital for 3 years]. 130 51

Serum amylase level was determined in 129 cases (225 episodes) of chronic respiratory failure at acute exacerbation and in 59 cases (62 episodes) of pneumonia without respiratory failure as control. Cases with accompanying diseases, such as acute pancreatitis, parotiditis, ileus and renal dysfunction, which were expected to develop hyperamylasemia were excluded. The 225 episodes were divided according to the causes of acute exacerbation into 4 groups: pneumonia, bronchitis, right heart failure without infection, and others (e. g. hemoptysis). Hyperamylasemia (greater than 400 S-U) was observed in groups of pneumonia (15/40 = 35.5%) and bronchitis (12/95 = 12.6%), respectively but not in those of right heart failure without infection (0/73 = 0%) and other causes (0/17 = 0%). As a result, hyperamylasemia was found only under conditions of inflammation of lung parenchyma and bronchi with acute exacerbation of respiratory failure. On the other hand no hyperamylasemia was observed in 62 episodes of pneumonia alone without respiratory failure. It was concluded that both respiratory tract infection and acute respiratory failure are necessary factors for development of hyperamylasemia originating from lung or bronchi.
Zhonghua Nei Ke Za Zhi 1992 Mar
PMID:[Hyperamylasemia in acute exacerbation of patients with chronic respiratory failure]. 138 26

17 cases with bronchial carcinoid were reported. 16 cases of them were proved pathologically after pulmonary resection, and the remaining one was confirmed histopathologically through bronchoscopic biopsy. 64.7% was under 40 years of age. The main clinical manifestations were cough, hemoptysis, fever and repeated pneumonitis. In one patient, the carcinoid was associated with Cushing's syndrome. Chest roentgenograms showed lesions centrally located in 12 cases, and peripherally located in 5 cases. Histological examination revealed 15 typical and 2 atypical carcinoid tumors. This disease was usually misdiagnosed as lung cancer, tuberculoma and benign tumors. Chest X-ray examination and fiberoptic bronchoscopic biopsy are helpful to the diagnosis of the disease. Pulmonary resection was performed in 16 cases. Two patients had hilar lymph node metastases, one of them had also involvement of pericardium. There was no operative mortality. In the follow-up study, the disease-free actuarial survival following pulmonary resection was 92.9% at 5 years. 2 patients died. One died of respiratory failure 4 months after pneumonectomy, the other died of pericardium involvement of carcinoid 8 months after operation. Resection is the only effective treatment for bronchial carcinoid.
Zhonghua Nei Ke Za Zhi 1992 May
PMID:[Bronchial carcinoid. A clinical, roentgenological and pathological study of 17 cases]. 147 26

90 patients diagnosed as eosinophilia and pulmonary infiltrates with peripheral eosinophilia in PUMC Hospital from 1957 to 1986 were reported. The cause of the eosinophilia was unknown in 42% of the patients. Among these patients, hypereosinophilic syndromes (HES) were suspected in 11 patients. The most common presenting symptoms of HES were fever, skin lesions gastrointestinal symptoms and hepatosplenomegaly, the mean peripheral blood eosinophil count was as high as 25.6 x 10(9) cells/L. Biopsies of bone marrow and involved organs revealed extensive eosinophilic infiltration and severe necrosis. In the past ten years, eosinophilia and pulmonary infiltrates caused by parasitic infections obviously decreased. The most common parasites were ascaris Lumbricoides, Ancylostoma duodenale and Clonorchis sinesis. The other main causes which induced pulmonary infiltrates were allergic bronchopulmonary mycosis (ABPM) and chronic eosinophilic pneumonia. The prevalence of ABPM increased recently; early diagnosis and effective therapy could prevent the irreversible damage resulting in airways obstruction and fibrosis.
Zhonghua Nei Ke Za Zhi 1990 Nov
PMID:[Clinical analysis of 90 cases of eosinophilia and pulmonary infiltrates with peripheral eosinophilia]. 208 6

A study of 62 cases of elderly pneumonia (EP) in their sixties and eighties with etiologic bacteria confirmed by cultures of sputum, blood or pleural effusion was carried out Greater change of etiologic bacteria of EP in patients of eighties has been found when they were compared with those of sixties. In the group of eighties the incidence of Gram-negative bacilli increased (77%), including pseudomonas aeruginosa (48.39%), Klebsiella pneumoniae (17.35%) and Enteric coli (9.68%), while Staphylococcus aureus accounted only for 16.1%. There were 2 species of Streptococcus pneumoniae; both were mixed with other bacteria in cultures. In patients of eighties the etiologic agents isolated from pneumonia were more resistant to many common antibiotics. The above mentioned results suggest that the diagnosis of etiology of pneumonia in the elderly should be emphasized.
Zhonghua Nei Ke Za Zhi 1989 Aug
PMID:[Evaluation of the causative bacteria of pneumonia in the elderly in recent years]. 268 7

This paper reports 100 cases of etiologically proved pneumococcal pneumonia. It is shown that Gram's stain smear and culture of sputum are still useful in the diagnosis of the disease but are easily influenced by antibiotics. Whereas coagglutination, a newly developed procedure in detecting pneumococcal capsular antigens, is relatively independent to antibiotic therapy. Moreover, it is rapid, convenient and sensitive. Both Gram's stain smear and coagglutination may confirm early diagnosis and are valuable in the initial treatment of the disease. If unhospitalized patients with acute pneumonia are checked routinely with these methods and samples are collected before administration of antibiotics, etiological diagnosis of pneumococcal pneumonia will be confirmed in more cases. The data from 100 cases of pneumococcal pneumonia demonstrates that pneumococcal pneumonia remains the most common type of community-acquired pneumonias in this country. Its clinical manifestations have not changed greatly since 1950s but the age of the afflicted tents to be greater especially in those with underlying diseases. There are two common types of roentgenographic manifestations, i.e., lobar consolidation and bronchopneumonia, the former is still overwhelming in those under sixty and the later is more frequently seen in those over sixty. Penicillin G showed good clinical effects in treating pneumococcal pneumonia and all the 57 strains tested were sensitive in vitro. Therefore, penicillin G is still the drug of first choice in treating pneumococcal pneumonia.
Zhonghua Nei Ke Za Zhi 1989 Jan
PMID:[Pneumococcal pneumonia: a report of 100 cases]. 273 30

115 cases of immunocompromised patients complicated with fungal pneumonia treated during the period from April 1968 to December 1986 were retrospectively studied. 96 were male and 19 female. Their age ranged from 6 to 84. The incidence increased significantly in recent years especially after 1983. Severe liver disease was the underlying disease in 102 (88.7%) patients. 108 (93.9%) had received antibiotics and 55 (47.9%) corticosteroids. Fungi species isolated were candida in 107 (54.9%), aspergillus in 82 (36.9%), penicillium in 7 (3.6%), mucormycetes in 6 (3%) and reotrichum in 3 (1.5%). Fever, cough, expectoration, moist rales diminished breath sounds and increase of W. B. C. and neutrophils were the important clinical features. The roentgenologic findings vary with the nature and extent of the pathologic process. Disseminated mycoses were found in 9 of the 18 autopsied cases. The characteristic pathologic findings were inflammation, abscess formation, vasculitis, infarction and hemorrhage. Extrapulmonary features such as enteritis, purulent nephritis, abnormal EKG, encephalopathy and rash were present. 93 cases received antifungal therapy including garlicin, clotrimazole, amphotericin B, nystatine, miconazole, 5-fluctosine and ketoconazole. Because these drug combinations were so complex, it is difficult to evaluate their efficiency. However the survival rate was somewhat elevated in recent years. The mortality rate of this series was 80.9%.
Zhonghua Nei Ke Za Zhi 1989 Jan
PMID:[A retrospective study of 115 cases of fungal pneumonia]. 273 37

Two cases of critical nosocomial pneumonia caused by flavobacterium meningosepticum (FM) were reported and both of them were successfully cured. There were 2 other cases of FM pneumonia reported in Chinese literature previously, but none of them survived. It has been found that the treatment for FM respiratory infection was very difficult because of its resistance to majority of antibiotics, including the third generation cephalosporins. The symptoms of FM pneumonia are similar to those of other gram-negative bacillus pneumonias, such as Klebsiella pneumoniae pneumonia. Definite diagnosis depends principally on etiological examination and clinical manifestations of pneumonia. Cefoperazone, Cefsulodin, Astreonam and Ciprofloxacin are valuable drugs in saving the lives of patients with FM Pneumonia.
Zhonghua Nei Ke Za Zhi 1994 Sep
PMID:[Antibiotic treatment for pneumonia caused by Flavobacterium meningosepticum]. 771 28

A prospective study for C. pneumoniae infection was conducted in 134 patients with acute respiratory disease and 134 matched patients with other medical reasons from January to May 1994 in Beijing. The positive rate of micro-IF (MIF) IgG antibodies was 93% (125/134) and 89% (119/134) respectively (0.1 < P < 0.25) and the geometric mean titers (GMT) were not found to be significant (55.9 +/- 4.2 vs 41.7 +/- 2.8, 0.1 < P < 0.20). Ten patients, four (4/30) with pneumonia and six (6/81) with bronchitis were serologically diagnosed as having recent C. pneumoniae infection. Chronic bronchitis was statistically more frequent in patients with C. pneumoniae infection than those without (0.025 < P < 0.05). Patients with chronic bronchitis (GMT, 87.1 +/- 3.9; n = 36) tended to have higher IgG titers than those without (GMT, 47.6 +/- 4.1; n = 98, 0.02 < P < 0.05). Culture of retro-pharyngeal swab specimens for C. pneumoniae was negative in the all 134 studied patients.
Zhonghua Nei Ke Za Zhi 1995 Jun
PMID:[Chlamydia pneumoniae infection in patients with pneumonia, bronchitis and acute upper respiratory tract infection in Beijing]. 858 86


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