Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Infectious mononucleosis (IM) is usually considered a benign disease. Agranulocytosis developed in a young college student 14 days after the onset of IM. Fulminant staphylococcal pneumonia and bilateral pulmonary infarcts resulted, and the patient died 4 1/2 hours after admission to a hospital. Agranulocytosis secondary to IM may be more prevalent than previously thought. A review of the literature indicated that infection developed in 57.9% of the patients with IM and extreme neutropenia and 45.4% of the infected patients died.
JAMA 1976 Sep 27
PMID:Infectious mononucleosis. Death due to agranulocytosis and pneumonia. 98 16

During a bronchological examination a massive endobronchial hemorrhage from the left bronchial system occurred in a 48 year old woman suffering from pneumonia of the right 6th segment of the lung. Successful treatment by use of a Carlens-tube with half-side blocking. Later on, the left lower lobe was removed by operation. Pathological findings showed multiple lung-infarctions. The possibilities of treatment are discussed in the case of endobronchial hemorrhage in the course of bronchological examinations.
Z Erkr Atmungsorgane 1976 Sep
PMID:[Massive endobronchial hemorrhage during bronchological examination-successful treatment by temporary half-side blocking by means of a Carlens-tube (author's transl)]. 102 30

Over a 12 month period, 61 isolates of methicillin-resistant Staphylococcus aureus (MR-SA) were obtained in 23 hospitalized patients. Eight-six per cent of the patients were over 50 years of age, and 91 per cent were in the postoperative period. In 10 patients (42 per cent), MR-SA was the major pathogen, producing either pneumonia, empyema, osteomyelitis, lung abscess, enterocolitis, wound infection or bacteremia with sepsis. Three patients in this group died despite therapy with antibiotics with in vitro activity against these organisms. All the patients probably acquired their MR-SA in the hospital, and five carriers of the organism were identified among hospital personnel. This outbreak demonstrates the ability of MR-SA not only to colonize many patients in a relatively brief period of time, but also to produce serious disease.
Am J Med 1976 Sep
PMID:Clinical, epidemiologic and bacteriologic observations of an outbreak of methicillin-resistant Staphylococcus aureus at a large community hospital. 104 60

Implications and course of fever were evaluated during hospitalization of 24 patients with acute myelogenous leukemia. Forty-five febrile episodes were identified. Fever present at admission was usually associated with a diagnosable and treatable infection; fever shortly after induction was self-limited; and fever during granulocytopenia was more likely to be associated with bacteremia. Bacteremia and pneumonia were the most common types of infection. Only Gram-negative bacteria and Candida were identified as causes of infection during life, with Pseudomonas and Klebsiella the most frequently isolated pathogens. Invasive candidiasis was a major postmortem finding. A delay in initiation of empirical treatment beyond the third day of fever was associated with an increase in mortality as was continuation of treatment for longer than 14 days.
Arch Intern Med 1975 Sep
PMID:Fever in acute myelogenous leukemia. 105 70

The purpose of this study was to characterize varicella in childhood cancer patients. Seventeen of the 77 patients reviewed were in remission and off all therapy for 3 to 22 months. No one in this group died from varicella or had evidence of visceral dissemination. Among the remaining 60 patients, all of whom were receiving anticancer theapy when they developed varicella, 19 (32%) had visceral dissemination and 4 died, for a mortality rate of 7%. Each of the deaths was associated with primary varicella pneumonitis, with or without acute encephalitis. Visceral dissemination was not related to type or status of malignancy or to duration of specific anticancer therapy. Varicella was more likely to disseminate in children with absolute lymphopenia, less than 500 cells per cubic millimeter, than in patients with higher lymphocyte counts. Cessation of anticancer theapy prior to the onset of lesions appeared to lessen the risk of dissemination. These results show that varicella is more severe in cancer patients on therapy than the general population or in patients who have completed therapy, but is not highly fatal.
Pediatrics 1975 Sep
PMID:Varicella in children with cancer: Seventy-seven cases. 108 28

A review of the medical literature and two case reports of M. pneumoniae infections with exanthems are presented. Erythematous maculopapular and vesicular exanthems were most common. The duration of rash was more than seven days in the majority of instances, and most patients had associated pneumonia. A striking difference in prevalence and clinical symptomatology by sex was noted; 16 of 20 patients analyzed were males, and they frequently dad severe mucocutaneous syndromes. In contrast, severe conjunctivitis, generalized ulcerative stomatitis, and vesicular or bullous exanthems were not seen in females. Clinicians should suspect infection with M. pneumoniae in patients with exanthem and pneumonia, although other etiologic possibilities should also be considered.
J Pediatr 1975 Sep
PMID:Mycoplasma pneumoniae infections and exanthems. 110 Jul 93

Study of five M. pneumoniae strains by the intensity of hemolysis and hemadsorption demonstrated no definite differences between them. Experiments on Cricetus auratus W. showed a higher virulence of the strains isolated from the patients with pneumonia in comparison with the strains isolated in acute respiratory diseases of the upper respiratory tracts. Attenuated straines were characterized by a weak intensity to reproduction in the lung tissue of Cricetus auratus W. and mildness of the histopathological changes which they caused.
Zh Mikrobiol Epidemiol Immunobiol 1975 Sep
PMID:[Results of a study of some methods of differentiating M. pneumoniae strains by the virulence of the degree of attenuation]. 110 83

Drug-induced noncardiogenic pulmonary edema occurred in a previously patient receiving dextran 40. Dextran 40 should be considered another etiologic factor of drug-induced noncardiogenic pulmonary edema when this syndrome occurs in the absence of known precipitating causes such as shock, aspiration, and overwhelming pneumonia.
Chest 1975 Sep
PMID:Dextran 40: another cause of drug-induced noncardiogenic pulmonary edema. 115 47

Pseudomonas putrefaciens, a marine organism infrequently found in human culture material, was repeatedly isolated from the sputum of a patient with pneumonia during a three-week period following a salt-water drowning accident. Similar organisms were found in the water at the site of the accident in Boston, and at ocean bathing beaches on nearby Martha's Vineyard.
Am J Clin Pathol 1975 Sep
PMID:Respiratory colonization with Pseudomonas putrefaciens after near-drowning in salt water. 116 89

Individual cases of influenza are not reported nationally to the Center for Disease Control (CDC). Other methods of surveillance, therefore, must be used to estimate the extent and impact of influenza in the country. In the past, CDC has performed telephone surveys during the respiratory season and tabulated mortality due to pneumonia and influenza from 121 cities. The telephone data vary considerably from state to state and are only a general assessment of influenza activity. Tabulation of influenza-pneumonia deaths reflects more accurately the extent and impact of influenza but suffers from a 3-4 week-lag behind the actual clinical events. To improve influenza surveillance over the past 2 years, CDC obtained weekly numbers of emergency room visits to large community hospitals, school and industrial absenteeism, numbers of specimens submitted and numbers positive for influenza isolation from laboratories throughout the United States. Surveillance was most effective in large urban areas of the US where community hospital emergency rooms function as private physicians. Where people are more likely to consult a private physician than utilize a hospital emergency room, the correlation between private physician visits and influenza was good. Furthermore, school and industrial absenteeism are not very sensitive indicators of influenza-A activity; however, school absenteeism was a good index of influenza-B activity.
Am J Epidemiol 1975 Sep
PMID:Influenza surveillance in the United States 1972-1974. 116 28


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