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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a study of a cohort of over 2000 children born between 1963 and 1965, the incidence of bronchitis and pneumonia during their first year of life was found to be associated with several family factors. The most important determinant of respiratory illness in these infants was an attack of bronchitis or pneumonia in a sibling. The age of these siblings, and their number, also contributed to this incidence. Parental respiratory symptoms, including persistent cough and phlegm, and asthma or wheezing, as well as parental smoking habits, had lesser but nevertheless important effects. Parental smoking, however, stands out from all other factors as the one most amenable to change in seeking to prevent bronchitis and pneumonia in infants.
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PMID:Influence of family factors on the incidence of lower respiratory illness during the first year of life. 100 69

In a 6-year prospective study of kerosene poisoning in children admitted to the Department of Paediatrics, University of Ilorin Teaching Hospital (UITH), between January 1982 and December 1987, 109 cases were seen. They were aged 6 months to 9 years, with a male: female ratio of 1.8:1. Majority (79.8%) were below 2 years. Many households (52.3%) stored the agent in familiar beverage or household containers placed on kitchen or bedroom floors, within easy reach of infants and toddlers. Seventy-six (69.7%) cases had home remedies, palm oil being the most common accounting for 55.3%. More than half of the cases (56.9%) presented within 12 hours of the accident due to persistent cough and dyspnoea. Respiratory complications viz pneumonia, pleural effusion and pulmonary oedema were the most common, evident in 67.3% of those who had chest radiographs. Approximately, three quarters (74.3%) of patients with radiologic abnormalities had palm oil alone or in combination with milk as home remedies. Severity of poisoning was influenced by the type of home remedy and the interval between accident and admission (P less than 0.05; P less than 0.01 respectively). Presence of radiological or CNS abnormality or both was associated with a higher morbidity. The only death in the study had complications referable to both systems. Ways of minimizing the risk of kerosene poisoning and its attendant morbidity are discussed.
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PMID:Kerosene poisoning in childhood: a 6-year prospective study at the University of Ilorin Teaching Hospital. 139 Mar 71

Persistent cough is a frequent and frustrating problem in the pediatric field. One hundred and seventy two children presenting with persistent cough for longer than 2 weeks were evaluated by both otolaryngologists and pediatricians. One hundred and twenty nine cases (75%) were found to have lower airway diseases, of which bronchial asthma, bronchitis and pneumonia, in that order, were the most common. One hundred and forty two cases (82%) had sinusitis, in 34 cases of which no causative diseases except sinusitis were found to be responsible for the persistent cough. Sinusitis was found in 90% of patients with pneumonia, 81% of those with bronchitis and 65% of those with poorly controlled asthma cases. These results revealed that sinusitis is an important causative factor for persistent cough in children. All the patients with pneumonia and bronchitis were cured by antibiotic administration for 2 weeks, whereas conservative treatment of sinusitis for as long as 6 months was less satisfactory resulting in only 60% cure, 18% improvement and 22% without improvement. In cases with sinusitis and lower airway diseases, continuous treatment for sinusitis is necessary even after treatment of the lower airway diseases has been completed.
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PMID:[Upper and lower airway diseases in children with persistent cough]. 140 14

A clinical AIDS case definition is needed for surveillance in countries where the CDC case definition is not practical. To derive such a definition, we compared 110 HIV-seropositive and 135 randomly selected HIV-seronegative adult medical-ward inpatients in Brazil. Multivariate analysis of clinical signs and symptoms and simple diagnoses resulted in a discriminant function with sensitivity of 89% and specificity of 96% in predicting for AIDS. These data were the empirical basis for a clinical definition of AIDS in adults drafted in a Caracas, Venezuela, workshop sponsored by the Pan American Health Organization. The revised "Caracas" definition presented here requires a positive HIV serology, the absence of cancer or other cause of immunosuppression, plus > or = 10 cumulative points, as follows: Kaposi's sarcoma (10 points); extrapulmonary/noncavitary pulmonary tuberculosis (10); oral candidiasis or hairy leukoplakia (5); cavitary pulmonary/unspecified tuberculosis (5); herpes zoster < 60 years of age (5); CNS dysfunction (5); diarrhea > or = 1 month (2); fever > or = 1 month (2); cachexia or > 10% weight loss (2); asthenia > or = 1 month (2); persistent dermatitis (2); anemia, lymphopenia, or thrombocytopenia (2); persistent cough or any pneumonia except TB (2); and lymphadenopathy > or = 1 cm at > or = 2 noninguinal sites for > or = 1 month (2). This definition has a sensitivity of 95% and a specificity of 100% (91% without HIV serology) when applied to the Brazilian patients in this study. The Caracas definition has been adopted by Brazil, Honduras, and Surinam, and is in validation elsewhere. The use of a reasonably sensitive and specific case definition commensurate with available diagnostic resources should facilitate AIDS surveillance in developing countries.
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PMID:A simplified surveillance case definition of AIDS derived from empirical clinical data. The Clinical AIDS Study Group, and the Working Group on AIDS case definition. 145 32

A-79-year old man, treated by thoracic fundoplication for hiatus hernia with symptomatic gastroesophageal reflux, 12 years previously, was examined for persistent cough and left basal pneumonia. Esophagogastroscopy revealed a gastrobronchial fistule which was confirmed by endoscopical fistulograms. Surgical treatment led to complete recovery of the patient. A review of the literature confirms the rarety of this ailment as well as the relevance of preoperative diagnosis by perendoscopical fistulograms.
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PMID:[Gastrobronchial fistula]. 147 10

Extrapulmonary infection with Pneumocystis carinii is an uncommon event in which the skin may be affected rarely. All cases heretofore described in immunocompromised hosts have involved the external auditory canal and mastoid areas. We describe two patients with acquired immunodeficiency syndrome and extrapulmonary cutaneous P carinii infection that involved the glabrous skin. The first was a 31-year-old white man seropositive for human immunodeficiency virus with prior episodes of P carinii pneumonia and infection with Mycobacterium avium-intracellulare evaluated for translucent papules on the skin with an appearance similar to molluscum contagiosum infection. Biopsy confirmed the diagnosis of cutaneous pneumocystosis. The second patient was a 36-year-old homosexual man with long-standing liver disease with a persistent cough, fever, and an abnormal chest roentgenogram. Cutaneous evaluation revealed a bluish macule on the sternal notch that on skin biopsy was diagnostic of cutaneous pneumocystosis. Treatment with intravenous pentamidine resulted in resolution of the pulmonary and cutaneous problems in both cases. Extrapulmonary P carinii infection may involve the skin at sites other than the external auditory canal and may have a nondescript appearance. Histologic findings are similar to those of pneumocystosis found elsewhere. Clinicians should be familiar with the nondescript nature of the eruption as skin biopsy may be helpful in establishing a diagnosis of systemic pneumocystosis.
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PMID:Cutaneous Pneumocystis carinii infection in patients with acquired immunodeficiency syndrome. 195 76

Endobronchial neoplastic disease is rarely encountered in patients under 20 years of age. The great majority of these lesions are carcinoids or mucoepidermoid carcinoma. Symptoms are secondary to bronchial irritation and manifest as recurrent pneumonitis, hemoptysis, persistent cough, reactive airway disease, and chest pain. Early bronchoscopy reliably enables identification and may prevent harmful sequelae resulting from delay in diagnosis. Retrospective data from four cases collected from the Tumor Registry in the Southern California Kaiser Permanente Medical Group is presented and a review of the literature is discussed.
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PMID:Endobronchial carcinoid and mucoepidermoid carcinoma in children. 200 93

A newly recognized chlamydial species, Chlamydia pneumoniae causes acute respiratory infections including pneumonia, bronchitis and pharyngitis. In this paper, eight cases of bronchitis and tonsillitis associated with C. pneumoniae are presented. Three cases came to the clinic because of persistent cough and productive sputum. C. pneumoniae was isolated from sputum of a patient and cultured in HeLa 229 cells. Other two patients were diagnosed serologically; Antibodies were measured by microimmunofluorescence using formalized elementary bodies of C. pneumoniae. A titer of 512 in the IgG class was detected. Four patients had sore throat. C. pneumoniae was isolated and cultured from tonsillar swabs in all of them. A patient with sore throat and cough diagnosed as pharyngolaryngitis was sero-positive. Antibodies to C. pneumoniae in IgG and IgM class were 128 and 32, respectively. All the patients were treated with macrolide antibiotics (erythromycin and rokitamycin), and clinical symptoms subsided. In five patients from whom the organism was isolated, the agents were eradicated by the treatment. However, clinical courses of those patients revealed that patient takes a long time to recover from the illness, if diagnosis and first choice of antimicrobial agent are not appropriate.
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PMID:[Respiratory tract diseases due to Chlamydia pneumoniae]. 204 Sep 12

Clinical and bronchographic data were juxtaposed with the results of selective histological examination of the resected parts of lungs from 3 to 14-year-old children suffering for several years from persistent cough and recurrent pneumonias. The defects of small and mean bronchi branching are found in 66% of cases (out of 50) and in 64% there was diverticulosis of the mucous membrane of large and small bronchi that is followed by pseudopoliposis and the development of deep "pouches". All this is followed by bronchus-associated lymphoid tissue hyperplasia, development of peribronchial pneumonia foci, chronic bronchitis, obturation syndrome.
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PMID:[Branching defects and mucosal diverticulosis of the bronchi in children as factors predisposing to the development of chronic inflammatory processes in the lungs]. 211 10

A neonatal pneumonia caused by Chlamydia trachomatis (C. trachomatis) is well-known. But it is uncertain whether C. trachomatis causes pneumonia in a patient over 1 year of age. Therefore, a search for serologic and cultural evidence of C. trachomatis infection in patients suffering from acute pneumonia over 1 year of age was made. We studied 183 children ages 1 to 5 year-old suffering from acute pneumonia admitted to Kousei General Hospital to assess the relation between acute pneumonia and C. trachomatis. We investigated the serologic evidence of acute C. trachomatis infections in 73 children with a persistent cough and wheezing, detecting specific IgG antibodies and IgM antibodies by microimmunofluorescence test. Serologic results signifying acute infection were observed in 4 cases (2.2%). Then we tried to isolate C. trachomatis from the cultures of nasopharyngeal swabs, specific inclusion bodies of C. trachomatis in 2 cases (1.1%) were found. Our study suggests that C. trachomatis might cause pneumonia in children over 1 year of age.
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PMID:[Investigation of Chlamydia trachomatis pneumonia in children]. 224 88


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