Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Abnormal breath sounds like wheezes are observed in patients with obstructive pulmonary diseases. The aim of this study was to construct an automatic technique for wheeze detection and monitoring using spectral analysis. Wheezes from 13 patients with diagnosed asthma, chronic obstructive pulmonary disease and pneumonia were recorded and a time-frequency wheeze detector (TF-WD) based on TF wheeze characteristics was constructed. The TF-WD was evaluated using 337 wheezes by comparing its findings with those from clinical auscultation performed by two experts. In addition, the TF-WD was tested against artificial noise. The experimental and testing results justified the efficient performance and high noise robustness of the TF-WD.
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PMID:Wheeze detection based on time-frequency analysis of breath sounds. 1711 64

The stethoscope is used as first line diagnostic tool in assessment of patients with pulmonary symptoms. However, there is much debate about the diagnostic accuracy of this instrument. This meta-analysis aims to evaluate the diagnostic accuracy of lung auscultation for the most common respiratory pathologies. Studies concerning adult patients with respiratory symptoms are included. Main outcomes are pooled estimates of sensitivity and specificity with 95% confidence intervals, likelihood ratios (LRs), area under the curve (AUC) of lung auscultation for different pulmonary pathologies and breath sounds. A meta-regression analysis is performed to reduce observed heterogeneity. For 34 studies the overall pooled sensitivity for lung auscultation is 37% and specificity 89%. LRs and AUC of auscultation for congestive heart failure, pneumonia and obstructive lung diseases are low, LR- and specificity are acceptable. Abnormal breath sounds are highly specific for (hemato)pneumothorax in patients with trauma. Results are limited by significant heterogeneity. Lung auscultation has a low sensitivity in different clinical settings and patient populations, thereby hampering its clinical utility. When better diagnostic modalities are available, they should replace lung auscultation. Only in resource limited settings, with a high prevalence of disease and in experienced hands, lung auscultation has still a role.
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PMID:The diagnostic accuracy of lung auscultation in adult patients with acute pulmonary pathologies: a meta-analysis. 3235 10