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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mycobacterial infections can be found in 10% of AIDS patients. Seventy cases with HIV+ infection were examined: they exhibited clear alterations of the chest and contemporaneous isolation and identification of mycobacteria. Primary tuberculosis is the most frequent manifestation in these patients. Alveolar parenchymal mono/bilateral infiltrates are the radiographic patterns of this pulmonary condition; they usually present without excavation (45.7%). Hilar and/or mediastinal lymph nodes are usually associated, and no pleural effusions. The main problem is the differential diagnosis with pneumocystis carinii pneumonia, especially the form involving lung apices. A correlation has been observed between the blood level of T-lymphocytes and their subsets (CD4 level) and the radiographic patterns of tuberculosis in AIDS patients. In fact, pleural effusion is frequent in patients with CD4 less than 200, while miliary nodules and cavitations are more frequent in the cases with CD4 greater than 200.
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PMID:[The radiological pictures of pulmonary tuberculosis in HIV+ patients]. 178 Apr 58

Index case is a 17-year-old boy who was admitted to our hospital with pleurisy and a minimal pulmonary lesion, and tubercle bacilli were recovered from pleural fluid. A diagnosis of primary tuberculosis was made based on the onset by pleurisy and the existence of hilar and mediastinal lymph node swelling. On the same day, a 76-year-old man, grandfather of the index case was admitted for precise examination of suspected extensive pneumonia. Tubercle bacilli were also isolated from the pus of infected bulla obtained by puncture. Neither of these two cases, however, seemed to be the source of the familial tuberculous infection because of such sudden onset of the disease as pleurisy and pneumonia. Two months later, a 46-year-old man, father of the index case was examined at our hospital. He was considered to be the source of the familial infection because he was diagnosed as tuberculosis with positive smear and a thick wall cavity (3.2 cm in diameter) on the left apex, and abnormal shadow was detected on his chest X-ray already two years ago. The fourth case was a mother of the index case, and wife of the third case, whose chest radiography revealed an infiltrative shadow on the right apex by a family contacts examination. Though tubercle bacilli were not isolated from her sputum, pulmonary lesions considered to be tuberculosis due to their typical location and nature, a positive PPD skin test, and the response to antituberculous drugs.
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PMID:[Four cases of simultaneous discovery of familial tuberculous infection]. 223 37

The authors have analyzed their experience in the diagnosis and treatment of 32 patients with broncholiths-induced obturation of the segmentary and lobar bronchi with subsequent prolonged recurring inflammatory, cirrhotic or suppurative bronchopulmonary processes farther to a site of bronchial obstruction. 37% of the patients only knew of primary tuberculosis. Chest pains were noted in 50%, hemoptysis in 40%. The rest of the symptoms were not characteristic. Therefore true diagnosis was established, as a rule, in a late period. Patients with broncholiths were treated for many years with the diagnosis of recurring pneumonia, cirrhotic or suppurative processes. Bronchoscopy is a method of choice because broncholiths can be found in a visible zone of the bronchial tree. The earlier bronchoscopy is performed, the easier and better can be the patients' cure.
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PMID:[Bronchial obturation by broncholiths as a cause of recurrent bronchopulmonary inflammatory processes and late recognition of the basic disease]. 360

Three hundred seventy-one adolescents and young adults, 10 to 20 years of age, were treated for tuberculosis during a 29-year period. There were 258 patients tuberculin positive without disease, 37 with calcifications on chest roentgenographs, and 76 with active tuberculous disease. All patients received chemotherapy. Active tuberculosis was more common in the 10- to 12-year-old patients. The greater number of tuberculin reactors in this age group suggests that endocrine factors related to the onset of puberty may play a role in conversion. No significant sex difference was apparent. Drug toxicity was rarely a problem. Pregnancy subsequent to therapy was not associated with progression or reactivation of disease. Two (possibly three) patients who were properly treated and compliant with the drug regimen had reactivation disease 4 to 14 years later. Cavitary pulmonary disease occurred in the two compliant patients. Meningitis, believed to be tuberculous, occurred in the suspected case. Two of these received isoniazid prophylaxis for skin test conversion only. In one patient, treated with two drugs for primary tuberculosis in the past, tuberculous pneumonia developed later. All three recovered. Although reactivation does occur, it is rare. Because most tuberculin reactors were discovered in the 10- to 12-year age group when screened routinely in high school, this procedure should not be abandoned.
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PMID:Perspectives in adolescent tuberculosis: three decades of experience. 374 73

In a working population of 912 men, aged 22 to 54 years, 8.3% reported a history of childhood respiratory illness before 16 years of age. Those reporting a history of bronchitis or pneumonia (BP) before 2 years of age had significantly lower FEV1 values than those who did not report such a history, whereas those reporting BP at a later age, or primary tuberculosis, did not have lower values. The observed association was unlikely to be due to preferential recall bias, since BP before 2 years of age was not associated with a higher reported prevalence of current respiratory symptoms of cough, phlegm, or dyspnea, and the observed association remained after exclusion of those with a history of wheezing or asthma. Furthermore, the relation remained significant after taking into account parental smoking, Pi phenotype and a history of eczema in childhood. These results suggest that BP before 2 years of age, a period of rapid alveolar multiplication, may be related to the occurrence of adult chronic air-flow limitation.
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PMID:Relationships between functional measurements and childhood respiratory diseases according to the age of onset. 381 75

Pulmonary tuberculosis is a chronic granulomatous disease characterized radiologically by nodules, air-space consolidation, propensity for cavitation, and calcification, and pathologically by caseating granulomas or pneumonia, and a great propensity for fibrosis and dystrophic calcification. Primary tuberculosis typically appears as air-space consolidation with hilar or mediastinal lymphadenitis. Postprimary tuberculosis appears most commonly as nodular and linear opacities at the lung apex. CT findings of early bronchogenic spread of postprimary tuberculosis are centrilobular 2- to 4-mm nodules or branching linear structure, 5- to 8-mm poorly defined nodules, lobular consolidation, cavities, and thickening of interlobular septa. Centrilobular nodules or branching linear lesions and poorly defined nodules on CT scan correspond to caseation materials filling the bronchioles, and centrilobular air-space consolidation with caseation necrosis. Poorly defined nodule or lobular consolidation usually consists of central caseation necrosis and peripheral nonspecific inflammation. Cavitation usually occurs at the centrilobular area and may progress to a larger coalescent cavity. With antituberculous therapy, resolution typically occurs from the peripheral portion of the poorly defined nodule or lobular consolidation and results in varying degrees of fibrous bands, bronchovascular distortion, emphysema, and bronchiectasis. Miliary tuberculosis appears as well-defined randomly distributed nodules on CT scan that correspond with nodules consisting of central caseation necrosis and peripheral epitheloid and fibrous tissue. Analysis of CT images on the basis of pathologic correlation is helpful in understanding the morphology of pulmonary tuberculosis.
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PMID:CT-pathology correlation of pulmonary tuberculosis. 754 70

Fifty-six autopsy protocols showing the presence of caseous pneumonia in babies and infants who died in 1947-1994 were examined. In the age group of children who died from caseous pneumonia (n = 88), babies and infants made up 63.6%. In 1947-1962, caseous pneumonia was found to frequently complicate a primary tuberculosis process both in babies (28.3%) and in 1-3-year-old infants (22.2%). At the same time lifetime tuberculosis was not recognized in 21.4% of cases and 26.8% died within the first 3 days of their hospital stay.
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PMID:[Caseous pneumonia in nursing and young infants (based on pathomorphological study data)]. 902 2

The authors' findings suggest that the clinical pattern of tuberculosis morbidity in adults and children has recently become worse. Severe caseous pneumonia with its acute onset and malignant course by the type of galloping consumption with massive bacterial isolation and deaths in 42.8% of cases was analyzed. The complicated course mainly of the primary tuberculosis complex (40.8%) and tuberculosis of the intrathoracic lymph nodes was seen in 25% of ill children. Tuberculous meningitis was diagnosed in 20% of cases in the morbidity pattern of extrapulmonary tuberculosis. The reasons for late detection of disease are the poor organization of prophylactic fluorographic examinations of the adult population, tuberculin diagnosis, vaccination, revaccination of BCG and chemoprophylaxis in children at risk. The authors note unawareness of tuberculosis among the adult population, which was found through questionnaires.
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PMID:[Clinical and X-ray characteristics of tuberculosis in adults and children and reasons for its late detection]. 916 28

Among 454 adults with various lung diseases, patients with calcified intrathoracic lymph nodes (CITLN) formed after latent and spontaneously cured primary tuberculosis infection were identified by computed tomographic findings. Among the patients with tuberculosis, there were 6% of cases with CITLN, 68% with central cancer, 46% with peripheral cancer, 37% with pneumonia. Among the patients with tuberculosis, CITLN as a possible source of reactivation of tuberculosis infection and occurrence of secondary tuberculosis had no substantial impact on the occurrence of secondary tuberculosis in adults. The pathogenetic significance of CITLN can be followed in malignant tumors, bacterial pneumonias, and in central cancer of the lung in particular.
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PMID:[Computed tomography in diagnosis of post-tuberculous intrathoracic lymphadenopathies]. 969 90

Prospective analysis for a period of six-and-a-half years was done in 190 patients with HIV infection, which showed post-primary tuberculosis with sputum positive for acid-fast bacilli in 65% of cases. Extrapulmonary forms of tuberculosis especially lymph nodes infection was more frequent. Cervical group of lymph node involvement was the commonest presentation. Procedures such as FNAC/biopsy of lymph nodes and pleura provided the immediate diagnostic yields. These procedures must be considered early in the course of illness of HIV infected patients with suspected extrapulmonary and disseminated tuberculosis. Tuberculosis constitutes a common pathology with an appreciable mortality in disseminated subjects. Majority of patients with tuberculosis responded to 2EHRZ/7HR therapy indicating infection by Mycobacterium tuberculosis rather than by atypical mycobacteria, without any serious adverse reactions. Retrospective analysis of two groups (February 1991-May 1994) and (June 1994-October 1997) shows a significant increase in disseminated tuberculosis and Pneumocystis carini pneumonia indicating late stage of HIV disease.
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PMID:Pattern of opportunistic pulmonary infections in HIV sero-positive subjects: observations from Pondicherry, India. 1053 38


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