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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An 11-year-old girl contracted pneumonia with consolidation of the left lower lobe, infiltrates in the lingula and left upper lobe, and a large left pleural effusion, accompanied by a Mycoplasma complement-fixation titer increasing to 1:16,384. Serial chest radiographs demonstrated resolution of the pneumonia and effusion, followed by development of a hyperlucent left lower lobe. This diagnosis was supported by abnormalities discovered by chest cinefluoroscopic examination and lung scans of ventilation and perfusion. Unilateral hyperlucent lung should be considered as a possible sequel to severe Mycoplasma pulmonary infection.
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PMID:Unilateral hyperlucent lung (Swyer-James syndrome) after severe Mycoplasma pneumoniae infection. 61 15

Serological surveys on several infections were performed on the inbred mouse strains maintained at the Central Institute for Experimental Animals. In the first survey, 11 strains of mouse, which were 8 weeks of age or older and were kept in separate cages in the same animal room, were tested for antibodies to Salmonella enteritidis, Corynebacterium kutscheri, Tyzzer's organisms, Mycoplasma pulmonis, mouse hepatitis virus (MHV), Sendai virus (HVJ), pneumonia virus of mice (PVM) and minute virus of mice (MVM). Positive results were obtained in MHV, HVJ, PVM and MVM. Positive rates for these viruses except for MVM were different among mouse strains. In the second survey, 5 strains of mouse kept together in the same cage for 4 weeks after weaning were examined for MHV and HVJ antibodies. Positive rates to MHV were different among mouse strains as observed in the first survey. For HVJ antibody, no difference was demonstrated in positive rates unlike in the first survey, but the titers varied between the strains. These results suggest the difference in antibody response to natural infections dependent on mouse strains.
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PMID:[Serological examinations on natural infections with mouse pathogens in inbred mouse strains: difference in antibody detection among the strains (author's transl)]. 63 Dec

Tracheobronchial clearance was studied in 17 non-smokers who had suffered from a serologically verified Mycoplasma pneumoniae pneumonia 5-15 months earlier. The subjects inhaled 6 micron teflon particles tagged with 99mTc. The retention of the particles in the lungs was measured for 2 h. The retention after 2 h in this group was significantly higher than in a control group of healthy non-smokers. The results suggest that some impairment persists 5-15 months after the infection or that persons with slow clearance contract a mycoplasma pneumonia more easily than do those with fast clearance.
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PMID:Tracheobronchial clearance 5-15 months after infection with Mycoplasma pneumoniae. 63 74

Mycoplasmas of the following species were isolated from the lungs of dog with distemper: Mycoplasma cynos, Mycoplasma bovigenitalium, Mycoplasma canis, Mycoplasma spumans, and Mycoplasma gateae. One-week-old dogs were inoculated endobronchially with cloned cultures of each species. M. cynos induced a focal pneumonia that were characterized histologically by severe inflammation of bronchi and adjacent respiratory tract tissue. The inflammatory response was initially neutrophilic and later was histiocytic with interstitial lymphoid hyperplasia. M. cynos was recovered from the lungs of inoculated dogs until three weeks after inoculation. A mild inflammatory response was observed in lung tissue of the dog inoculated with M. bovigenitalium, whereas M. canis, M. spumans, and, M. gateae did not induce any visible lesions.
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PMID:Canine mycoplasmas: pathogenicity of mycoplasmas associated with distemper pneumonia. 68 96

In a retrospective morphological and microbiological study, 39 of 55 cases of bovine fibrinous pneumonia were diagnosed as fibrinous pleuropneumonia. Twenty-nine of these 39 (74%) were associated with Pasteurella hemolytica, but only two cases (5%) with P. multocida. In contrast, of the 16 cases classified as fibrinous bronchopneumonia, one (6%) was associated with P. hemolytica, and nine (56%) with P. multocida. In eight cases Mycoplasma and Hemophilus somnus were found in association with either P. hemolytica or P. multocida but were never isolated alone. We concluded that the use of the term pasteurellosis, implying Pasteurella as the cause, is imprecise because lesions associated with P. hemolytica fulfill the criteria of a fibrinous pleuropneumonia, whereas P. multocida is more likely to cause a bronchopneumonia with moderate amounts of fibrin.
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PMID:Correlation of microbiological and histological findings in bovine fibrinous pneumonia. 68 79

An inactivated Mycoplasma pneumoniae vaccine was prepared from a culture in a liquid medium supplemented with water extract of egg yolk. Vaccinated Syrian hamsters were exposed to virulent M. pneumoniae aerosol and were examined for the retention of mycoplasmas and for histopathological changes in the respiratory tracts. When a vaccine prepared with strain FH was administered intramuscularly or by inhalation in aerosol, no significant resistance was shown with respect to mycoplasma proliferation. An increased resistance, however, was observed when an aluminium phosphate-adsorbed vaccine, and when a plain vaccine (although to a lesser degree) prepared with hamster 24-passaged strain FH, was administered intramuscularly. Histopathologically, lung lesions were markedly suppressed in groups showing high resistance. A correlation between the serum antibody titer and the resistance to infection was observed. Hamsters which received a hyperimmune rabbit antiserum intracordally showed a high resistance to M. pneumoniae infection. The suppression of histopathological changes also coincided with high complement-fixing antibody titers of either actively or passively immunized hamster serum. The results suggest that humoral immunity plays an important role in resistance to M. pneumoniae pneumonia in hamsters.
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PMID:Acquired immunity to Mycoplasma pneumoniae. Pneumonia in hamsters. 69 61

The radiological appearances and the progress of the pulmonary manifestations of serologically-proven acute Mycoplasma pneumoniae infection were studied in 29 patients. The radiological changes seen at and after admission were not helpful in establishing an aetiological diagnosis except in three patients, in whom a "classical" pattern of mycoplasma pneumonia, based on the radiological appearnaces at different histopathological stages of the disease, could be recognised retrospectively. The patterns seen were varied and generally non-specific, and were not related to the age of the patient or to the duration of disease prior to admission. Specific anti-mycoplasma therapy may have prevented the progress of the disease after admission, although five of six patients in whom radiological deterioration occurred after admission were receiving such treatment.
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PMID:Radiographic patterns of pulmonary involvement in acute mycoplasmal infections. 69 74

139 cases of Mycoplasma pneumoniae infection (serological diagnosis) were treated at Aurora Hospital, Helsinki, between January 1975 and August 1977. In 123 patients the main diagnosis was respiratory infection; 114 of these had pneumonia. The frequency of complications was high: 8 patients had neurologic, 6 cardiac and 5 joint symptoms. Although a significant rise in titre of complement-fixing antibodies to M. pneumoniae was required, the low titre level in some patients who had manifestations less frequently associated with M. pneumoniae infection may suggest nonspecific reactions. Nearly half of the patients in this study had plasmocytosis in the peripheral blood suggesting a strong antibody response. This might be connected with some serological reactions detected in association with M. pneumoniae infections.
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PMID:Clinical and laboratory manifestations in patients with serological evidence of Mycoplasma pneumoniae infection. 72 39

Here are the most important pathomorphological findings recorded from 14 calves or heads of young cattle following whole-body X-ray treatment (170 R and u50 R median-line dosage): 1. Damage was caused to the haematopoietic system, with the most severe effects on granulopoiesis, thrombocytopoiesis, and lymphopoiesis, but less conspicuous lesion of erythropoiesis. 2. Haemorrhagic diathesis developed together with pneumonia in 86 per cent of all cases, manifested in most of them as severe fibrinous pneumonia and pleuropneumonia (in 75 per cent of the cases) and progressing pericarditis. 3. Liver degeneration occurred to all animals, usually in the form of centrobular liver cell necrobiosis (86 per cent), with most of the cases accompanied by diffuse degenerative hepatoparenchymal damage (80 per cent) as well as by granular degeneration of the myocardium and acute fubulonephrosis, the latter two processes obviously developing only short time before death. 4. Catarrhal as well as fibrinous and circumscribed diphtheroid enteritis developed in 43 per cent of all animals, those which had received a median-line dosage of 170 R. 5. Deficiency in supply was recorded, too, with severe damage to the haematopoietic organs being in the focus of the pathological process. That damage actually was the cause of the haematologically established granulocytopenia or agranulocytosis, thrombocytopenia, and lymphopenia. That was the background against which radiation syndrome of calf could be accompanied by activation of latent or subclinical infection of respiratory organs and the development of severe pneumonia as well as by changes in the intestinal flora leading to the outbreak of enteritis. The collapse of cellular defence mechanisms obviously caused intestinal induction of resorption of bacterial toxins and decomposed tissue products, with the pneumonia-damaged lungs being involved. The results eventually were intoxication with haemodynamic disorders, increase in vascular permeability, and degenerative damage to the parenchyma. Haemorrhagic diathesis was the result of thrombocytopenia and, possibly, endotoxic or toxic damage to the coagulation and blood vessel system. Further pathogenetic aspects relating to the radiation syndrome in calf and young cattle are discussed.
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PMID:[Pathomorphology and pathogenesis of radiation sickness in calves and young cattle following whole body roentgen irradiation]. 72 76

An outbreak of illness due to Mycoplasma pneumoniae occurred among employees of a large hospital. The spectrum of disease ranged from severe upper respiratory infection to multilobed pneumonia. No unusual increase in the incidence of respiratory illness due to this organism was observed in the surrounding community during the period under investigation. It was not possible to identify any single area of the hospital frequented by enough of the involved personnel to explain the spread of the infection among the hospital's employees. This is the first outbreak of M pneumoniae disease to be reported among hospital personnel.
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PMID:Outbreak of Mycoplasma pneumoniae infection among hospital personnel. 73 56


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