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Query: UMLS:C0032285 (pneumonia)
 54,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chlamydia trachomatis may cause trachoma, pneumonia, urogenital infection, conjunctivitis and lymphogranuloma venereum, etc. This paper reviews the effects of monotherapy, combined antibiotic regimens, and drug resistance during the treatment of Chlamydia trachomatis infection.
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PMID:[Advances in the treatment of Chlamydia trachomatis infection]. 1592 Dec 64

Toxins, which resemble in most respects bacterial endotoxins, are associated with the agents of lymphogranuloma venereum, meningopneumonitis, and mouse pneumonitis as they grow in the yolk sac of the chick embryo. They are labile and are not readily separated from the bodies of the agent. They kill mice rapidly after intravenous, and in some cases after intraperitoneal, injection but the minimal lethal dose is relatively large and, in those freshly harvested yolk sacs which have been tested, has corresponded to about 36 million infective units. Characteristic lesions are produced in all mice except those which die very rapidly, and are found especially in the liver where necrosis of the midzone of the lobule occurs. Antitoxic sera which are effective against a few lethal doses of the toxin can be produced in rabbits or chickens by using either toxin or toxoid as antigen. Such sera behave in a manner analogous to antiendotoxins against bacterial endotoxins and they do not neutralize by the law of multiple proportions. Antitoxic sera can also be obtained from human beings convalescent from at least one of these diseases. The toxins and antitoxins appear to be highly specific and they may offer a useful tool in distinguishing between different members of this closely interrelated group.
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PMID:STUDIES ON LYMPHOGRANULOMA VENEREUM : II. THE ASSOCIATION OF SPECIFIC TOXINS WITH AGENTS OF THE LYMPHOGRANULOMA-PSITTACOSIS GROUP. 1987 82

1. A pneumotropic virus which forms elementary bodies has been isolated from apparently normal albino Swiss mice. 2. The antigenic relationship of this virus to those of meningopneumonitis, lymphogranuloma venereum, hamster pneumonia (7), and human pneumonitis (8) was established either by cross-immunity or complement fixation or both. 3. In spite of a relationship to other viruses, the virus could be differentiated from all the others studied by certain of its properties.
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PMID:ISOLATION FROM NORMAL MICE OF A PNEUMOTROPIC VIRUS WHICH FORMS ELEMENTARY BODIES. 1987 84

Chlamydia comprises a group of obligate intracellular bacterial parasites responsible for a variety of diseases in humans and animals, including several zoonoses. Chlamydia trachomatis causes diseases such as trachoma, urogenital infection and lymphogranuloma venereum with severe morbidity. Chlamydia pneumoniae is a common cause of community-acquired respiratory tract infections. Chlamydia psittaci, causing zoonotic pneumonia in humans, is usually hosted by birds, while Chlamydia abortus, causing abortion and fetal death in mammals, including humans, is mainly hosted by goats and sheep. We used multi-locus sequence typing to asses the population structure of Chlamydia. In total, 132 Chlamydia isolates were analyzed, including 60 C. trachomatis, 18 C. pneumoniae, 16 C. abortus, 34 C. psittaci and one of each of C. pecorum, C. caviae, C. muridarum and C. felis. Cluster analyses utilizing the Neighbour-Joining algorithm with the maximum composite likelihood model of concatenated sequences of 7 housekeeping fragments showed that C. psittaci 84/2334 isolated from a parrot grouped together with the C. abortus isolates from goats and sheep. Cluster analyses of the individual alleles showed that in all instances C. psittaci 84/2334 formed one group with C. abortus. Moving 84/2334 from the C. psittaci group to the C. abortus group resulted in a significant increase in the number of fixed differences and elimination of the number of shared mutations between C. psittaci and C. abortus. C. psittaci M56 from a muskrat branched separately from the main group of C. psittaci isolates. C. psittaci genotypes appeared to be associated with host species. The phylogenetic tree of C. psittaci did not follow that of its host bird species, suggesting host species jumps. In conclusion, we report for the first time an association between C. psittaci genotypes with host species.
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PMID:Multi locus sequence typing of Chlamydia reveals an association between Chlamydia psittaci genotypes and host species. 2115 37


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