Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
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Query: UMLS:C0032273 (
pneumoconiosis
)
1,578
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The relationship between biochemical changes in bronchoalveolar lavage fluid (BALF), serum and the lung of different dustexposed rats was studied. Wistar rats were divided into 5 groups: 1. Xingkong chrysotile asbestos (CH-As); 2. Dust in a sieve selection workshop of Xingkong asbestos mine (Dust-Wo); 3. Silica group (SiO2); 4. Titanium dioxide (TiO2) and 5. Normal control group (Control). All the rats were killed in three months after experiment. The results showed that the level of alveolar macrophages (AM), lactic dehydrogenase (LDH) and acid phosphatase (AcP) in each group was marked by related to collagen, lung fat, ceruloplasmin (Cp) and hydroxyproline (HoP) by r and t-test. Among the LDH from BALF, culture fluid and serum, there was also a marked relationship. So the authors pointed out that the BALF especially AM and LDH test could serve as a good and valuable index for detection the condition of
pneumoconiosis
.
Hua
Xi Yi Ke Da Xue Xue Bao 1991 Sep
PMID:[The relationship of biochemical changes among bronchoalveolar lavage fluid serum and lung on dust-exposed rats]. 166 Aug 48
A comparative study of chest roentgenograms and the value of RV/TLC% in determining degree of emphysema of patients with
pneumoconiosis
and workers exposed to dust was made in 400 cases. Accordance rate of RV/TLC% with roentgenograms in determining emphysema in the same subjects was 61.1% and that in the patients group, 67.7%. Moreover, the accordance rate increased with grade of
pneumoconiosis
diagnosed. The results showed that RV/TLC% was valuable in determining emphysema of patients with
pneumoconiosis
. The classes of degree of emphysema were proposed according to the testing value of RV/TLC%.
Hua
Xi Yi Ke Da Xue Xue Bao 1991 Jun
PMID:[The value of residual volume testing in determining degree of emphysema in patients with pneumoconiosis]. 178 57