Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0032273 (
pneumoconiosis
)
1,578
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Activity of purine metabolism enzyme,
adenosine deaminase
(
ADA
) in lymphocytes and erythrocytes from patients with
pneumoconiosis
and chronic bronchitis was determined.
ADA
activity decrease was found in lymphocytes and erythrocytes for both decreases. The observed decrease of
ADA
activity indicates that after the long term work in mineral dust industry damage of purine metabolism takes place, that is similar to the disturbance observed under secondary immunodeficiency. Changes in activity of superoxide dismutase and catalase show some decrease of functional activity of anti-radical protection. Therefore the results obtained can be used for the selection of a group with highest risk of predisposition to these diseases.
...
PMID:[Changes in adenosine deaminase and antioxidative enzyme activity in patients with lung diseases of dust etiology]. 179 56
