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Query: UMLS:C0032273 (pneumoconiosis)
 1,578 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Since it is very rare that cardiac tamponade due to myocardial rupture caused by infective endocarditis, occurs we are reporting this case. A 62 year old man, who had underlying diseases of pneumoconiosis and hypertensive heart disease, visited Chikuho Rosai Hospital complaining of chest oppression and general fatigue on Feb. 7, 1987. He was diagnosed as having ischemic heart disease by electrocardiogram. Two days later, he suddenly had chills and a fever, and the laboratory data showed leukocytosis and a positive C-reactive protein (CRP). The echo cardiogram showed mitral regurgitation (MR) and aortic regurgitation (AR), but neither vegetation nor pericardial effusion was observed. On Feb. 16, he was admitted with shock, and he died the next day. The blood cultures grew gram-positive cocci, respectively. From the clinical symptoms, chest roentgenogram and electrocardiogram, we suspected a cardiac tamponade. On autopsy findings, though coronary arteries were intact, the aortic valves had severe valvular adhesions, calcifications and hypertrophies. The rupture hole was observed in the left ventricles, which was just under the aortic valve through the pericardiac space. It seemed that he died of a cardiac tamponade due to the outflow of blood from this hole. On histopathologic findings of the cardiac wall, gram-positive cocci and many of neutrophils were observed.
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PMID:[An autopsied case of infective endocarditis with cardiac tamponade due to myocardial rupture]. 207 73

Exercise testing can answer several pertinent questions for the physician. It can determine whether a worker's aerobic performance is limited by respiratory or by other factors. It can also help decide whether an individual can perform a job without undue physiologic limitations and fatigue. Exercise testing has its limitations. It cannot determine the etiology of the impairment nor can it make a specific diagnosis except in rare cases. Interpretation of exercise data is not always precise, especially when the VO2max is normal but several physiologic measurements are abnormal. The VO2max achieved under laboratory conditions is probably too simplistic an estimate of the complex energy requirements of any occupation. Future research is needed to develop portable devices to assess both aerobic and anaerobic potentials of workers on the job to better determine job-specific impairment and disability. Patients who have unexplained symptoms or abnormal, but not severely reduced, static pulmonary function tests benefit most from exercise testing. For now, the AMA criteria for impairment as defined by static and exercise pulmonary function testing are the most appropriate to follow. Exercise testing has provided valuable data for epidemiologic research. Descriptive and case-control studies have documented minor physiologic abnormalities and rare respiratory limitations in workers with asbestos exposure and simple coal worker's pneumoconiosis. Additional studies are necessary to further elucidate pathophysiologic findings in patients with asbestosis and other occupationally induced pulmonary diseases.
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PMID:Cardiopulmonary exercise testing to assess respiratory impairment in occupational lung disease. 330 79

A 60-year-old man with pneumoconiosis complained of general fatigue, exertional dyspnea, and anorexia. The patient had severe anemia, and laboratory examination revealed autoimmune hemolytic anemia with positive direct and indirect Coombs tests. After corticosteroid therapy, the anemia resolved markedly, and the antinuclear antibody test became negative. However, the silicotic shadow on chest X-ray film showed no remarkable change. The autoimmune hemolytic anemia in this case was probably due to an immunological disturbance caused by silicosis.
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PMID:[Silicosis associated with autoimmune hemolytic anemia]. 858 25