Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0032273 (pneumoconiosis)
1,578 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Silicosis and coal worker's pneumoconiosis (CWP) are two relatively common occupational diseases. Silicosis is the most common pneumoconiosis in the United States. It results from inhalation of the particulate form of quartz or other crystalline forms of silicon dioxide with a diameter of less than 5 micrograms. CWP is the result of inhalation of carbon particles. Pathologic features of the two diseases differ, yet their radiologic features are identical. Simple pneumoconiosis is characterized by multiple small rounded opacities of 1 to 5 mm in diameter and with a bias for the upper lung zones. Complicated pneumoconiosis results from confluence of small opacities into large opacities that form conglomerate masses or progressive massive fibrosis.
...
PMID:Standard imaging in silicosis and coal worker's pneumoconiosis. 141 Mar 5

Progressive massive fibrosis is a recognized complication of pneumoconiosis secondary to pulmonary fibrosis, with retraction forming conglomerate masses symmetrically in the upper lobes. Idiopathic pulmonary hemosiderosis is known to cause pulmonary fibrosis secondary to recurrent alveolar hemorrhage with deposition of hemosiderin in the interstitium. We present a case in which progressive massive fibrosis developed in a patient with long-standing idiopathic pulmonary hemosiderosis.
...
PMID:Progressive massive fibrosis associated with idiopathic pulmonary hemosiderosis. 832 91

Progressive massive fibrosis (PMF) secondary to pneumoconiosis involves the formation of fibrotic masses that eventually cause death from multiple complications. We present a rare but potentially serious complication in a patient with coal pneumoconiosis with PMF, in whom the appearance of paroxysmal melanoptysis was attributed to the cavitation of one of the pneumoconiotic masses. We emphasize the need for differential diagnosis to exclude other more common causes, as well as the use of bronchoscopy for diagnosis and confirmation. Strict control is needed to prevent possible respiratory failure when melanoptysis is massive.
...
PMID:[Paroxysmal melanoptysis secondary to the cavitation of pulmonary pneumoconiosis conglomerate]. 907 36