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Query: UMLS:C0032273 (
pneumoconiosis
)
1,578
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Abnormal Q waves have been generally considered to be one of the most reliable indicators of permanent myocardial cell death, namely myocardial infarction. Pathological and experimental studies also support this concept. However, some cases of abnormal Q waves disappearing after myocardial infarction have been reported. Recently, we observed acute myocardial infarction with
pneumoconiosis
. In this case, a patient with abnormal Q waves appeared within 24 hours after the onset of acute myocardial infarction. But, thirteen days later, these abnormal Q waves disappeared on the surface twelve-lead ECG. The precise mechanism for regression or disappearance of abnormal Q waves is not yet well known. Several studies pointed out a relation of this phenomenon to myocardial collateral circulation under
ischemia
. And, Nonkin et al reported that, patients with chronic lung disease such like
pneumoconiosis
, had high incidence of collateral circulation to the myocardium. This was due to chronic hypoxic conditions. In our case, cineangiographic study could not be performed, but disappearance of abnormal Q wave (so called Transient abnormal Q waves), following acute myocardial infarction may be related to the presence of chronic lung disease.
...
PMID:[Transient abnormal Q waves under acute myocardial infarction in patients with pneumoconiosis]. 233 Apr 57
The aim of this study was to evaluate the oxidative status in patients with silicosis by detecting dynamic thiol disulfide homeostasis (TDH),
ischemia
-modified albumin level (IMA) catalase (CAT) activity, and the correlation of these markers with pulmonary function tests. Male ceramic workers with silicosis (
n
= 91) and healthy individuals (
n
= 47) were recruited for the study. Radiographic abnormalities of
pneumoconiosis
were classified into three profusion categories (categories 1, 2, and 3), and patients with silicosis, those with category 1, were defined as group 1 and those with category 2 or 3 were defined as group 2. Plasma levels of native thiol (NT), total thiol (TT), disulfide (Ds), IMA, and CAT activities were determined. Pulmonary function tests of groups were compared. NT, TT, and NT/TT ratios were significantly lower in groups 1 and 2 than the control group (
p
< 0.05). These did not differ between patients with silicosis (groups 1 and 2) and control group (
p
= 0.421). Ds/NT and Ds/TT ratios were significantly higher in group 2 than the control group (
p
< 0.05). NT, TT, and Ds did not differ significantly between groups 1 and 2. The oxidant biomarker IMA was higher (
p
< 0.001), and the antioxidant parameters albumin and CAT were lower in groups 1 and 2 (
p
< 0.001) compared with the control group. The mean FEV
1act
, FVC
act
, forced expiratory volume in 1 second/forced vital capacity (%), and value of 25-75 percent maximum expiratory flow were significantly lower in groups 1 and 2 than control group. We have used a novel colorimetric method to assess TDH in patients with silicosis. Alteration of plasma thiol/disulfide homeostasis and IMA levels might be novel indicators of oxidative stress in silicosis.
...
PMID:Alteration of thiol disulfide homeostasis and ischemia-modified albumin levels as indicators of oxidative status in patients with silicosis. 3330 88
