Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0031511 (
pheochromocytoma
)
14,622
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PCC
5109
Sep
1003
nerve growth factor
955
Mol
784
polypeptide
318
ATP
317
RET
303
tyrosine hydroxylase
236
SDHB
206
PGL
200
caspase-3
197
calcitonin
190
She
184
NGF
178
ferredoxin
169
MRI
166
AMP
157
insulin
157
Bcl-2
145
CO2
144
neurofibromatosis
141
cytochrome
141
epidermal growth factor
139
VHL
136
RET proto-oncogene
127
renin
123
Adrenomedullin
123
NMR
122
NADPH
121
tyrosine kinase
118
chromogranin A
117
fused
115
superoxide dismutase
109
somatostatin
107
cytochrome c
107
SDS
103
ACTH
103
reductase
102
SDHC
101
catalase
99
ERK1
95
lactate dehydrogenase
91
GTP
86
NF1
86
adrenomedullin
84
ERK
83
GSH
81
p38
80
endoplasmic reticulum
76
c-fos
76
adenylate cyclase
75
phosphatase
73
neurofibromatosis type 1
72
ATPase
71
membrane-bound
69
ADP
69
proto-oncogene
69
synaptophysin
67
NADP
67
MAPK
66
extracellular signal-regulated kinase
66
amyloid precursor protein
65
collagen
65
transcriptional regulator
64
neurotrophin
63
p75NTR
63
MEN2A
63
NAD
61
beta-endorphin
61
p53
61
mitogen-activated protein
60
EPR
60
prothrombin
60
membrane protein
60
ACS
60
calmodulin
59
glutamine synthetase
58
glucagon
58
peroxidase
58
CP47
58
MEK
57
NADH
57
Pol
57
thioredoxin
56
threonine
56
SDHA
55
neurotrophic factor
55
Chlamydomonas
54
unknown function
54
cytochrome b
54
dimeric
53
oxidoreductase
53
FDG
53
calcium channel
52
glutathione peroxidase
52
glycoprotein
50
MAX
49
MAP kinase
48
receptor tyrosine kinase
48
acetylcholinesterase
48
TMEM127
47
neuron-specific enolase
46
Gen
46
axonal
46
hemoglobin
45
ras
45
SOD
44
amyloid beta
44
ABC
43
bradykinin
42
methyltransferase
40
von Hippel-Lindau tumor suppressor
40
alkaline phosphatase
39
dopamine beta-hydroxylase
39
ACC
39
SDH
39
phosphatidylinositol 3-kinase
38
p21
37
Pseudomonas
36
c-Jun
36
neuropeptide Y
36
brain-derived neurotrophic factor
36
heme oxygenase-1
35
NADP+
35
angiotensin II
35
PI3K
34
AKT
34
PKC
34
adenylyl cyclase
34
non-functional
33
apoE
33
fibronectin
33
vascular endothelial growth factor
32
pVHL
32
Met
32
cytochrome c oxidase
32
tRNA
31
GDP
31
GAF
31
MTC
31
lipopolysaccharide
30
Mal
30
tumor necrosis factor
30
mTOR
30
interleukin-6
30
ROS
30
heat shock protein
30
metallothionein
29
ATP synthase
29
LDH
29
TOF
29
CREB
29
AP-1
29
ornithine decarboxylase
29
cAMP-dependent protein kinase
28
growth hormone
28
thymus
28
TNF
28
nitric oxide synthase
28
beta 1
28
more...
Disease
pheochromocytoma
14622
PCC
5109
tumor
2609
hypertension
1396
cancer
944
paraganglioma
733
multiple endocrine neoplasia
635
medullary thyroid carcinoma
531
Hippel
482
metastases
431
neuroblastoma
427
adenoma
289
carcinoma
282
Cushing's syndrome
269
adrenal mass
266
Alzheimer's disease
266
MEN 2
260
aldosteronism
214
renal cell carcinoma
178
cardiomyopathy
177
diabetes
172
hyperparathyroidism
156
essential hypertension
141
MEN 2B
138
tumorigenesis
138
Conn
136
neurofibromatosis type 1
136
Parkinson's disease
130
neurofibromatosis
125
carcinoid
113
heart failure
108
SDS
103
ganglioneuroma
94
adrenocortical carcinoma
94
secondary hypertension
90
hemangioblastoma
89
primary hyperparathyroidism
87
cold
87
stroke
85
neuroendocrine tumor
84
glioma
83
GSH
81
myocardial infarction
79
pulmonary edema
73
renal artery stenosis
72
ischemia
72
depression
64
lymphoma
63
hypercortisolism
63
melanoma
62
adenocarcinoma
62
pertussis
60
tumor growth
57
metastatic pheochromocytoma
55
primary tumor
55
adrenal adenoma
52
hyperglycemia
50
hyperthyroidism
50
Cushing's disease
50
hypercalcemia
50
congestive heart failure
46
hepatocellular carcinoma
46
hypoglycemia
44
renal failure
43
obesity
42
parathyroid hyperplasia
42
adrenal insufficiency
41
carcinogenesis
40
hemangioma
40
pituitary adenoma
39
sarcoma
38
cerebral ischemia
38
MTC
37
MEN1
36
acromegaly
36
leukemia
36
schwannoma
36
SEM
36
ganglioneuromatosis
36
rare disease
36
renal disease
35
thyroid cancer
35
hypothyroidism
35
dementia
35
heart disease
34
iron deficiency
34
lung carcinoma
34
malignant hypertension
33
myocardial ischemia
33
acute myocardial infarction
32
insulinoma
32
coronary artery disease
31
dilated cardiomyopathy
31
breast cancer
30
bone metastases
30
preeclampsia
30
sepsis
29
Benson
29
cardiovascular disease
29
tumor progression
28
sepsis
28
chronic renal failure
28
cholera
27
adrenal hyperplasia
27
liver metastases
27
white coat hypertension
27
Malignant pheochromocytoma
27
myocarditis
26
epilepsy
26
familial cancer
25
carcinoid syndrome
24
glucose intolerance
24
prostate cancer
24
dehydration
24
cognitive impairment
23
glioblastoma
23
astrocytoma
23
acute pulmonary edema
22
stromal tumors
22
anemia
22
encephalopathy
22
gastrointestinal stromal tumor
21
epididymis
21
neuroma
21
parkinsonism
21
ventricular hypertrophy
21
obstructive sleep apnea
21
tuberculosis
21
recurrent pheochromocytoma
21
lung cancer
21
amyloidosis
21
herpes simplex
20
schizophrenia
20
benign tumor
19
genetic disorder
19
aggressiveness
19
Neuroblastoma
18
Neuroblastoma
18
dysplasia
18
leiomyosarcoma
18
squamous cell carcinoma
18
coagulopathy
18
WT1
17
adrenal hypertension
17
lichen
17
migraine
17
proteinuria
17
asthma
17
Best
17
Malignancy
17
thyroid nodule
17
rhabdomyosarcoma
17
angiomyolipoma
17
renal cancer
17
hypertensive encephalopathy
17
chlorosis
17
uterus
17
Bladder
16
panic disorder
16
tetanus
16
more...
Symptom
headache
328
anesthesia
197
starvation
184
pain
103
abdominal pain
90
nausea
63
chest pain
62
collapse
49
vomiting
49
diarrhea
48
flushing
44
dyspnea
41
seizures
36
dizziness
29
weakness
28
angina
27
syncope
25
fatigue
25
excessive sweating
22
pallor
20
back pain
20
flank pain
19
tremor
15
spasm
15
discomfort
15
constipation
14
discomfort
14
analgesia
14
polyuria
13
cough
12
shortness of breath
11
nausea and vomiting
10
epigastric pain
10
acute abdomen
10
Cushingoid
8
hypothermia
8
Paroxysmal hypertension
7
ataxia
7
chills
7
polydipsia
7
erythema
7
Cushingoid
7
hemoptysis
7
respiratory distress
7
masculinization
6
fever of unknown origin
6
hyperoxia
6
cyanosis
6
anorexia
6
sleepiness
6
tinnitus
6
Ill
6
abdominal discomfort
6
insomnia
6
low back pain
5
twitching
5
snoring
5
bone pain
5
overweight
5
acidity
5
tachypnea
4
lethargy
4
cachexia
4
agitation
4
hemiplegia
4
acute abdominal pain
4
despair
4
memory loss
4
asthenia
3
myalgia
3
functional recovery
3
neck pain
3
exhaustion
3
vertigo
3
hepatomegaly
3
alexithymia
3
thinning
3
wheezing
3
hypercapnia
3
stridor
3
dysuria
3
facial pain
3
distraction
3
tingling
2
numbness
2
asynergy
2
chest tightness
2
iliac fossa pain
2
paraparesis
2
splenomegaly
2
skin damage
2
Gastrointestinal symptoms
2
chronic constipation
2
regurgitation
2
Depressive symptoms
2
HSA
2
Decreased activity
2
catatonia
2
dystonia
2
bloating
2
renal colic
2
labored breathing
2
enuresis
2
right upper quadrant pain
2
blurred vision
2
shoulder pain
2
fasciculation
2
abnormal gait
2
Mills
1
Psychotic Symptoms
1
Hudson
1
POA
1
periorbital edema
1
stigma
1
difficulty with urination
1
acute pain
1
precordial pain
1
hot flashes
1
unable to sleep
1
hunger
1
hypoproteinemia
1
Signs and Symptoms
1
Sedation
1
cerebellar ataxia
1
presyncope
1
hot flushes
1
syncopal episodes
1
decreased appetite
1
leg pain
1
persistent cough
1
dark urine
1
paresis
1
orthopnea
1
pedal edema
1
hypalgesia
1
paresthesia
1
exertional dyspnea
1
pleuritic chest pain
1
generalized pain
1
rib pain
1
productive cough
1
apathy
1
Induced hypothermia
1
nasal congestion
1
physical appearance
1
tense
1
clubbing
1
Fetal bradycardia
1
drooling
1
spasticity
1
abnormal breathing
1
Anoxia
1
consciousness disturbance
1
Watery diarrhea
1
dental pain
1
acute stress
1
bradykinesia
1
arthralgia
1
bitter taste
1
hypertonia
1
more...
Drug
Cardiovasc
73
lysine
64
NADH
58
Gel
56
ABC
43
Nephron
34
MTC
31
ascorbate
31
ROS
30
Asn
26
FAD
26
p75
23
Dermatol
23
nitroglycerin
21
K-252a
21
Clonidine
18
DNase I
18
Carotenoid
17
PTH
16
Forskolin
15
Ethanol
14
BH4
14
caffeine
14
vitamin E
13
Heme
13
MAP
13
L-tyrosine
12
Angiotensin II
10
CSF
10
Glucagon
10
PCB
10
CaCl2
9
HCH
9
CaCl2
9
Phentolamine
9
Glutathione
9
CaCl2
9
LCM
8
NaI
8
NaI
8
Leaf
8
MgSO4
8
pyridoxal phosphate
8
NaI
8
ETA
8
LCM
8
PTC
8
ENT
8
NaI
8
PCP
8
citric acid
8
TAC
7
DMSA
7
Reserpine
7
Activin
6
ALA
6
MEA
5
CTX
5
Dibenzyline
5
Vitamin K
5
Apomorphine
5
Nephron
5
THF
5
TTC
5
IFN-gamma
5
Vitamin E
4
Sodium nitroprusside
4
Monit
4
Estrogens
4
Glycerol
4
Propofol
4
Fraction
4
Spectrum
4
ROC
4
Nitric Oxide
4
OctreoScan
4
ACT
4
CAM
4
ETS
3
CoCl2
3
Asthma
3
Portal
3
Monensin
3
Alanine
3
IL-2
3
Fructose
3
Retinoic acid
3
FeCl3
3
CoCl2
3
Paraffin
3
Lovastatin
3
Regitine
3
Taxol
3
CTA
3
Mutagen
3
Rutin
3
Fluorescein
3
ampicillin
3
ADM
2
CET
2
Indomethacin
2
lactose
2
Ginseng
2
Inderal
2
G418
2
Albumin
2
NAG
2
Ketoconazole
2
EPA
2
CEG
2
RFP
2
CPM
2
SiO2
2
Guanidine
2
OTC
2
VCR
2
Adosterol
2
EHDP
2
Diurnal
2
Cardura
2
Biopolymers
2
BoNT/A
2
ICI
2
OTC
2
Guanidine
2
IL-1ra
2
Triclosan
2
Methyltyrosine
2
Ringer's solution
2
Secretin
2
Sinemet
2
PPA
2
CEG
2
Timolol
2
Dial
2
Bifidobacterium
2
DMI
2
Tubocurarine
2
Magnesium sulfate
2
EE2
2
HCG
2
Cetrorelix
2
NVP
2
CDP
2
Enalaprilat
1
MDM
1
Oxaliplatin
1
Everolimus
1
Phenytoin
1
Trandate
1
Tocopherol
1
Etoposide
1
Epigallocatechin
1
Intron A
1
Sandostatin
1
Propidium
1
Furan
1
DPA
1
Prozac
1
Amifostine
1
more...
Enzyme
ERK
428
mitogen-activated protein kinase
308
protein kinase
277
tyrosine hydroxylase
232
succinate dehydrogenase
193
caspase-3
174
protein kinase C
152
superoxide dismutase
129
catalase
129
renin
123
nitrogenase
97
lactate dehydrogenase
95
MEK
84
adenylate cyclase
80
ATPase
74
luciferase
73
peroxidase
68
hydrogenase
65
ACS
62
hydrogenase
62
PAL
61
RNA polymerase
61
acetylcholinesterase
60
histidine kinase
60
glutamine synthetase
58
monoamine oxidase
56
glutathione peroxidase
53
phospholipase C
47
trypsin
47
alkaline phosphatase
39
nitrate reductase
38
reverse transcriptase
38
nitrate reductase
38
chloramphenicol acetyltransferase
38
nitrate reductase
38
phosphatidylinositol 3-kinase
38
nitrate reductase
38
nitrate reductase
36
nitrate reductase
36
NQO1
35
complex I
34
dopamine beta-hydroxylase
34
AMPK
32
ATP synthase
31
glucose-6-phosphate dehydrogenase
30
ornithine decarboxylase
29
phosphodiesterase
28
phospholipase A2
28
diaphorase
27
glutathione S-transferase
25
caspase-9
25
adrenodoxin reductase
25
calcineurin
25
focal adhesion kinase
25
endonuclease
24
beta-galactosidase
24
peroxiredoxin
23
RNase
23
thrombin
23
choline acetyltransferase
22
guanylate cyclase
22
RNase
22
PARP
22
NADPH-diaphorase
22
NADPH oxidase
21
glutathione reductase
21
phenylethanolamine N-methyltransferase
21
nitrite reductase
20
nitrite reductase
20
MPP
20
nitrite reductase
20
GSK
19
glutamate synthase
19
rubisco
19
CaMKII
19
cytochrome oxidase
19
NADH dehydrogenase
18
bidirectional hydrogenase
18
proteasome
18
ACE
17
cholinesterase
17
alcohol dehydrogenase
17
heme oxygenase
17
phospholipase D
17
glutamate synthase
17
enolase
17
propionyl-CoA carboxylase
17
pyruvate dehydrogenase
17
aldolase
16
thromboplastin
16
phosphorylase
16
glutamate synthase
16
ADP-glucose pyrophosphorylase
16
thioredoxin reductase
15
carbonic anhydrase
15
glyceraldehyde-3-phosphate dehydrogenase
15
glyceraldehyde-3-phosphate dehydrogenase
14
propionyl-CoA carboxylase
14
APC
13
MAP
13
glyceraldehyde-3-phosphate dehydrogenase
13
DOPA decarboxylase
13
caspase-8
13
NADPH oxidase
13
glyceraldehyde-3-phosphate dehydrogenase
13
glyceraldehyde-3-phosphate dehydrogenase
13
phosphoenolpyruvate carboxylase
12
MMP-3
12
NO synthase
12
6-phosphogluconate dehydrogenase
12
6-phosphogluconate dehydrogenase
12
isocitrate dehydrogenase
12
isocitrate dehydrogenase
12
phosphoinositide 3-kinase
11
SPS
11
aromatic L-amino acid decarboxylase
11
diaphorase
11
lysozyme
11
HtrA
11
lipoxygenase
11
thymidine kinase
10
S1 nuclease
10
phosphoenolpyruvate carboxykinase
10
phosphoenolpyruvate carboxykinase
10
phosphoenolpyruvate carboxykinase
10
IscS
10
tissue plasminogen activator
9
AMP-activated protein kinase
9
alanine aminotransferase
9
PAL
9
PTPase
9
FtsH protease
9
cdc2
9
prolyl hydroxylase
9
fumarase
9
GTP cyclohydrolase I
9
chaperonin
8
glycine decarboxylase
8
cGMP phosphodiesterase
8
21-hydroxylase
8
protochlorophyllide oxidoreductase
8
gamma-glutamylcysteine synthetase
8
acyl-ACP synthetase
8
arginine decarboxylase
8
aspartate aminotransferase
8
PCP
8
gamma-glutamyl kinase
8
citrate synthase
8
sphingosine kinase
8
xanthine oxidase
8
creatine kinase
8
Mg-chelatase
8
NOS
8
phosphoribulokinase
7
plasmin
7
malate dehydrogenase
7
ferrochelatase
7
PRE
7
collagenase
7
neuraminidase
7
more...
Compound
Dec
1055
DNA
1014
oxygen
883
nitrogen
727
Clin
696
calcium
594
glucose
360
iron
356
water
347
sodium
325
ATP
317
phosphate
304
His
293
hydrogen
291
tyrosine
290
cAMP
272
noradrenaline
227
CO2
220
salt
208
cysteine
193
nitrate
178
Adrenal
169
glutamate
168
arginine
163
AMP
163
sulfate
154
aldosterone
154
acetate
144
methionine
136
ammonium
135
Cardiol
134
serine
128
alanine
124
MTT
122
NADPH
121
NADPH
121
H2O2
120
manganese
118
iodine
112
NADP
111
ACTH
106
threonine
106
SDS
105
ethanol
104
lysine
101
nitric oxide
100
copper
100
zinc
93
potassium
91
GTP
89
GSH
87
GSH
87
2-oxoglutarate
86
Asp
78
bromide
71
ADP
70
ADP
69
ADP
69
NAD
69
urea
67
Phe
67
leucine
66
VMA
65
glutamine
65
L-DOPA
65
NAD
61
galactose
61
ACS
60
NH2
60
ACS
60
NADH
58
pentose
56
creatinine
56
pentose
55
pentose
55
Mg2+
55
pentose
55
DCMU
52
cyanide
51
cadmium
51
PEG
50
MEK
49
Gly
49
Dopamine
46
phosphorus
46
cGMP
46
glycerol
45
carbonate
43
guanidine
39
nickel
38
cobalt
38
methanol
37
tryptophan
37
aspartic acid
35
retinoic acid
34
tryptophan
33
proline
33
Triton X-100
32
EDTA
32
Ile
32
tryptophan
32
tryptophan
32
EDTA
32
MTC
31
GDP
31
Neuronal
30
aldehyde
30
TOF
29
Norepinephrine
29
PEG
29
TNF
28
aspartic acid
28
asparagine
28
ammonia
28
aldehyde
27
FAD
26
CAT
26
aspartic acid
25
aspartic acid
25
acetic acid
25
vinyl
24
Thyroid
24
CAT
24
CAT
24
GM1
23
acetyl-CoA
23
ADP-ribose
23
TCA
23
CoA
22
succinic acid
22
glutamic acid
22
Insulin
21
DTPA
21
Glutamate
21
COS
20
HCO
20
Dexamethasone
20
MPP
20
N-acetylcysteine
20
MPP
20
fluorine
19
MPTP
19
diacetate
19
barium
19
DEAE
18
MDA
18
pyridine
18
acridine
18
1-butanol
18
pyrimidine
17
pyrimidine
17
alcohol dehydrogenase
17
Chlorophyll
17
adenylate
16
ornithine
16
ornithine
16
mercury
16
UDP-glucose
16
ornithine
16
UTP
16
more...