Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0031350 (pharyngitis)
 2,405 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a group of children with acute, nonstreptococcal pharyngitis, only one (2%) of the 44 children tested showed serologic or direct-immunofluorescence evidence of a recent Chlamydia trachomatis infection. Only two (5%) of the 43 children tested showed serologic evidence of a recent Mycoplasma pneumoniae infection. Neither C. trachomatis nor M. pneumoniae appears to be an important cause of acute pharyngitis in children.
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PMID:Role of Chlamydia trachomatis and Mycoplasma pneumoniae in acute pharyngitis in children. 310 49

This study determined the prevalence rates of Chlamydia trachomatis infection in the oropharynx of adolescents with and without pharyngitis. One hundred teenagers with and without symptoms of pharyngitis were cultured for C. trachomatis. Swabs were taken from the oropharynx and tonsillar areas for direct fluorescent antibody assay and cell culture. Of the 100 adolescents enrolled in the study 55% had a history of pharyngitis and 45% had no pharyngeal symptoms; 29% were male and 71% were female. The mean age was 15.5 years. Forty-two percent had a history of sexual intercourse, and 11.5% described a history of oral-genital sex. Only one 14-year-old female with a 2-week history of a sore throat had a positive culture. Her direct fluorescent antibody assay was inconclusive and the throat culture for Group A Streptococcus was negative. She had no history of sexual activity. The overall prevalence rate in the 100 adolescents was 1% with a 1.8% prevalence in the symptomatic group and 0 in the asymptomatic group. Of the symptomatic adolescents 39 had cultures for Group A Streptococcus and 8 (20.5%) were positive. The results of this study suggest that C. trachomatis is a rare inhabitant of the oropharynx in adolescents and is not a common cause of pharyngitis.
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PMID:Low prevalence of Chlamydia trachomatis in the oropharynx of adolescents. 354 Aug 87

The paper presents current knowledge about the clinical course, diagnostic and treatment of chlamydial infections in the neonatal period. In the neonatal period, infections caused by Chlamydia trachomatis are in the majority of maternal origin. Chlamydia mother to child transmission occurs during vaginal birth. It can also occur but rarely, during caesarean section after premature rupture of membranes. Chlamydia trachomatis infection of the genitourinary system in pregnancy increases the danger of intrauterine growth restriction and foetal death. It rises the perinatal morbidity of foetuses and newborns and increases the risk of premature deliveries. Chlamydia trachomatis infection in newborns manifests as conjunctivitis and ophthalmia and less commonly as pharyngitis and otitis media. Erythromycin is applied in prophylaxis and treatment of Chlamydia infections.
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PMID:Chlamydia infections in the neonatal period. 1608 67