Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0031117 (peripheral neuropathy)
10,577 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
axonal 979
Sep 665
insulin 381
Mol 244
She 168
GBS 164
MRI 156
hemoglobin 115
proteasome inhibitor 105
CD4 104
X-linked 98
proteasome 90
albumin 88
transthyretin 87
TNF 77
B12 76
nerve growth factor 73
myelin-associated glycoprotein 70
cytokine 70
IgA 69
CSF 63
Cx32 63
endoplasmic reticulum 61
interferon 55
tumor necrosis factor 51
aldose reductase 49
vascular endothelial growth factor 47
CMT1A 46
peripheral myelin protein 22 46
PMP22 46
calcitonin 41
myelin protein zero 40
glycoprotein 39
IL-6 39
collagen 39
chronic renal failure 37
ATP 36
substance P 36
caspase-3 35
membrane-bound 34
DRG 34
M-protein 31
granulocyte colony-stimulating factor 31
lymphoid 31
asymmetrical 31
CMT1 29
ATPase 29
gut 29
thymidine phosphorylase 28
tRNA 28
p38 28
creatine kinase 27
non-Hodgkin's lymphoma 27
myelin basic protein 27
HER2 27
HLA 26
sodium channel 25
ALD 25
nodal 25
Pol 25
p24 antigen 24
ubiquitin 24
rheumatoid factor 24
glial fibrillary acidic protein 24
MAG 24
superoxide dismutase 24
calcium channel 24
CMT2 23
cytochrome P450 23
neurotrophin 23
neurotrophic factor 23
CD8 22
CHOP 22
granulocyte 22
TRPV1 22
interleukin-6 21
Proteasome 21
brain-derived neurotrophic factor 21
nitric oxide synthase 21
platelet-derived 21
more...
Disease
peripheral neuropathy 10577
neuropathy 2482
diabetes 1563
cancer 1074
polyneuropathy 671
multiple myeloma 432
Charcot-Marie-Tooth disease 408
diabetic neuropathy 391
neutropenia 370
HIV 355
tumor 315
type 2 diabetes 309
vasculitis 294
thrombocytopenia 268
AIDS 263
retinopathy 259
anemia 236
hypertension 232
autonomic neuropathy 228
cold 225
sensory neuropathy 218
myopathy 206
renal disease 205
encephalopathy 204
breast cancer 191
dementia 183
amyloidosis 178
hyperglycemia 176
immunodeficiency 174
depression 162
stroke 152
lymphoma 148
myelopathy 143
carpal tunnel syndrome 138
chronic pain 136
type 1 diabetes 128
myelosuppression 127
cognitive impairment 121
cardiomyopathy 119
rash 116
colorectal cancer 113
leukopenia 111
multiple sclerosis 110
leprosy 110
gammopathy 109
muscular atrophy 108
neurological disease 106
obesity 104
systemic lupus erythematosus 103
peripheral vascular disease 100
Frey 100
renal failure 97
cryoglobulinemia 96
mononeuropathy 94
metastases 93
carcinoma 91
POEMS syndrome 90
epilepsy 89
ovarian cancer 87
ischemia 87
non-small cell lung cancer 85
Hodgkin's disease 84
Parkinson's disease 84
deafness 84
proteinuria 82
rheumatoid arthritis 81
metastatic breast cancer 80
malnutrition 79
parkinsonism 75
hypoglycemia 74
leukemia 73
heart failure 72
arthritis 71
alcoholism 71
lactic acidosis 69
sepsis 69
leukoencephalopathy 69
mononeuritis 68
optic atrophy 67
mental retardation 67
more...
Symptom
pain 1449
weakness 547
ataxia 374
fatigue 243
diarrhea 237
numbness 224
seizures 201
nausea 197
paresthesia 191
vomiting 191
cerebellar ataxia 168
headache 140
tremor 115
nausea and vomiting 106
myalgia 102
constipation 97
ophthalmoplegia 93
abdominal pain 78
arthralgia 75
tingling 68
spasticity 63
sleepiness 62
paraparesis 60
anesthesia 59
Neuropathic pain 58
dysarthria 58
dizziness 56
anorexia 55
hypotonia 50
dystonia 47
dyspnea 46
analgesia 46
paresis 44
discomfort 43
asthenia 43
discomfort 37
splenomegaly 37
cachexia 36
hepatomegaly 36
dysesthesia 32
insomnia 31
hepatosplenomegaly 30
Ill 29
back pain 28
chorea 28
myoclonus 27
erythema 25
acute pain 23
cough 22
angina 21
ataxic gait 19
cancer pain 18
neuralgia 17
low back pain 16
abnormal gait 16
memory loss 16
thinning 16
fasciculation 15
collapse 14
functional recovery 14
overweight 14
tinnitus 13
vertigo 13
intention tremor 12
syncope 12
muscle cramps 12
dry eye 12
livedo 12
lethargy 11
chest pain 11
bone pain 10
hemiplegia 10
hoarseness 10
respiratory distress 10
incoordination 9
neurological disability 9
Lhermitte's sign 8
blurred vision 8
agitation 7
apathy 7
more...
Drug
Bortezomib 136
Oxaliplatin 117
Taxol 84
Dermatol 70
CSF 67
vitamin E 43
Docetaxel 29
Pregabalin 26
AZT 24
AZT 24
Posture 24
ddI 21
Vitamin B 20
Domperidone 19
Duloxetine 19
G-CSF 16
Cardiovasc 15
Rituximab 15
Adriamycin 14
lysine 14
Gabapentin 14
CTX 13
Cremophor EL 13
Lenalidomide 13
Vitamin B12 12
pyridoxal phosphate 12
CPT-11 11
ADM 11
Vindesine 11
ascorbate 11
Vindesine 11
DM1 10
CTC 10
niacin 10
p75 10
CTC 10
Taxotere 10
Vinorelbine 9
Vitamin E 8
ROC 8
Leucovorin 8
Perhexiline maleate 7
ALA 7
Dial 7
Ixabepilone 6
Epalrestat 6
Ethanol 6
Isoniazid 6
ROS 6
Simvastatin 6
Asthma 5
CTX 5
PTH 5
Monit 5
CTX 5
Prednisone 5
Navelbine 5
Tapentadol 5
NADH 5
Infliximab 4
Herceptin 4
Bevacizumab 4
Alliance 4
Asn 4
Arsenic trioxide 4
Parkin 4
Miglustat 4
Infliximab 4
Tacrolimus 4
Fludarabine 4
Parkin 4
Phenytoin 4
HCG 4
ENT 3
ABC 3
Glutathione 3
Amifostine 3
Prednisolone 3
IFN-gamma 3
Gastro 3
more...
Enzyme
proteasome 91
reverse transcriptase 77
ERK 63
mitogen-activated protein kinase 54
aldose reductase 49
protein kinase C 42
creatine kinase 39
protein kinase 39
ATPase 35
focal adhesion kinase 32
thymidine phosphorylase 28
superoxide dismutase 28
peroxidase 23
caspase-3 21
catalase 18
acetylcholinesterase 17
DNA polymerase 16
ACS 16
alkaline phosphatase 15
alanine aminotransferase 14
kinesin 13
phosphodiesterase 13
PARP 13
pyruvate dehydrogenase 12
RNA polymerase 12
MEK 12
ACE 12
cytochrome oxidase 12
renin 12
CYP3A4 11
asparaginase 11
cholinesterase 11
aspartate aminotransferase 11
AMP-activated protein kinase 10
lactate dehydrogenase 10
transcriptase 9
3-hydroxyacyl-CoA dehydrogenase 9
transketolase 9
P-glycoprotein 9
CPT 9
SPT 9
AST 9
tyrosine hydroxylase 8
dihydropyrimidine dehydrogenase 8
complex I 8
porphobilinogen deaminase 8
CD10 7
arylsulfatase A 7
CPT 7
glutathione peroxidase 7
3-hydroxyacyl-CoA dehydrogenase 7
sulfatase 7
AMPK 7
PDK1 7
dihydropyrimidine dehydrogenase 6
glutathione S-transferase 6
endonuclease 6
CPT 6
lysozyme 6
NO synthase 6
luciferase 6
AMPK 6
ceruloplasmin 6
pyruvate dehydrogenase 6
pyruvate dehydrogenase 6
glycyl-tRNA synthetase 6
CYP27A1 6
BAL 6
succinate dehydrogenase 6
phosphatidylinositol 3-kinase 6
MDR 6
prostate-specific antigen 5
methylenetetrahydrofolate reductase 5
calcineurin 5
alpha-galactosidase 5
adenylate cyclase 5
15-lipoxygenase 5
ALA synthase 5
GSK 5
MTD 5
more...
Compound
Clin 973
Dec 732
glucose 364
DNA 324
Paclitaxel 184
calcium 173
creatinine 135
water 130
oxygen 128
sodium 127
DDP 95
Neo 83
TNF 77
His 74
ethanol 69
Vincristine 66
potassium 56
phosphate 51
NAD 49
d4T 48
glutamate 48
hexane 45
acrylamide 41
GM1 37
urea 37
nitric oxide 37
methionine 37
ATP 36
sulfate 36
nicotinamide 35
copper 35
zinc 35
2,5-hexanedione 33
serine 31
AZT 30
DPN 29
acetone 29
iron 28
5-FU 28
noradrenaline 27
arginine 26
Insulin 26
Docetaxel 26
Capsaicin 25
vitamin D 25
galactose 25
L-carnitine 24
tyrosine 24
Diabetol 24
acetate 24
Diabetol 24
mercury 23
tryptophan 23
homocysteine 23
nitrogen 23
STZ 22
threonine 22
NIDA 22
Neuronal 22
leucine 21
Arsenic 20
lysine 20
CBDCA 19
hydrogen 19
CBDCA 19
folinic acid 18
Cardiol 18
cysteine 18
GSH 17
Adriamycin 17
NMDA 17
GSH 17
ACS 16
Lead 16
Thiamine 16
ACS 16
GABA 15
NAD 15
GABA 15
proline 15
more...