Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0031117 (
peripheral neuropathy
)
10,577
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
axonal
979
Sep
665
insulin
381
Mol
244
She
168
GBS
164
MRI
156
hemoglobin
115
proteasome inhibitor
105
CD4
104
X-linked
98
proteasome
90
albumin
88
transthyretin
87
TNF
77
B12
76
nerve growth factor
73
myelin-associated glycoprotein
70
cytokine
70
IgA
69
CSF
63
Cx32
63
endoplasmic reticulum
61
interferon
55
tumor necrosis factor
51
aldose reductase
49
vascular endothelial growth factor
47
CMT1A
46
peripheral myelin protein 22
46
PMP22
46
calcitonin
41
myelin protein zero
40
glycoprotein
39
IL-6
39
collagen
39
chronic renal failure
37
ATP
36
substance P
36
caspase-3
35
membrane-bound
34
DRG
34
M-protein
31
granulocyte colony-stimulating factor
31
lymphoid
31
asymmetrical
31
CMT1
29
ATPase
29
gut
29
thymidine phosphorylase
28
tRNA
28
p38
28
creatine kinase
27
non-Hodgkin's lymphoma
27
myelin basic protein
27
HER2
27
HLA
26
sodium channel
25
ALD
25
nodal
25
Pol
25
p24 antigen
24
ubiquitin
24
rheumatoid factor
24
glial fibrillary acidic protein
24
MAG
24
superoxide dismutase
24
calcium channel
24
CMT2
23
cytochrome P450
23
neurotrophin
23
neurotrophic factor
23
CD8
22
CHOP
22
granulocyte
22
TRPV1
22
interleukin-6
21
Proteasome
21
brain-derived neurotrophic factor
21
nitric oxide synthase
21
platelet-derived
21
more...
Disease
peripheral neuropathy
10577
neuropathy
2482
diabetes
1563
cancer
1074
polyneuropathy
671
multiple myeloma
432
Charcot-Marie-Tooth disease
408
diabetic neuropathy
391
neutropenia
370
HIV
355
tumor
315
type 2 diabetes
309
vasculitis
294
thrombocytopenia
268
AIDS
263
retinopathy
259
anemia
236
hypertension
232
autonomic neuropathy
228
cold
225
sensory neuropathy
218
myopathy
206
renal disease
205
encephalopathy
204
breast cancer
191
dementia
183
amyloidosis
178
hyperglycemia
176
immunodeficiency
174
depression
162
stroke
152
lymphoma
148
myelopathy
143
carpal tunnel syndrome
138
chronic pain
136
type 1 diabetes
128
myelosuppression
127
cognitive impairment
121
cardiomyopathy
119
rash
116
colorectal cancer
113
leukopenia
111
multiple sclerosis
110
leprosy
110
gammopathy
109
muscular atrophy
108
neurological disease
106
obesity
104
systemic lupus erythematosus
103
peripheral vascular disease
100
Frey
100
renal failure
97
cryoglobulinemia
96
mononeuropathy
94
metastases
93
carcinoma
91
POEMS syndrome
90
epilepsy
89
ovarian cancer
87
ischemia
87
non-small cell lung cancer
85
Hodgkin's disease
84
Parkinson's disease
84
deafness
84
proteinuria
82
rheumatoid arthritis
81
metastatic breast cancer
80
malnutrition
79
parkinsonism
75
hypoglycemia
74
leukemia
73
heart failure
72
arthritis
71
alcoholism
71
lactic acidosis
69
sepsis
69
leukoencephalopathy
69
mononeuritis
68
optic atrophy
67
mental retardation
67
more...
Symptom
pain
1449
weakness
547
ataxia
374
fatigue
243
diarrhea
237
numbness
224
seizures
201
nausea
197
paresthesia
191
vomiting
191
cerebellar ataxia
168
headache
140
tremor
115
nausea and vomiting
106
myalgia
102
constipation
97
ophthalmoplegia
93
abdominal pain
78
arthralgia
75
tingling
68
spasticity
63
sleepiness
62
paraparesis
60
anesthesia
59
Neuropathic pain
58
dysarthria
58
dizziness
56
anorexia
55
hypotonia
50
dystonia
47
dyspnea
46
analgesia
46
paresis
44
discomfort
43
asthenia
43
discomfort
37
splenomegaly
37
cachexia
36
hepatomegaly
36
dysesthesia
32
insomnia
31
hepatosplenomegaly
30
Ill
29
back pain
28
chorea
28
myoclonus
27
erythema
25
acute pain
23
cough
22
angina
21
ataxic gait
19
cancer pain
18
neuralgia
17
low back pain
16
abnormal gait
16
memory loss
16
thinning
16
fasciculation
15
collapse
14
functional recovery
14
overweight
14
tinnitus
13
vertigo
13
intention tremor
12
syncope
12
muscle cramps
12
dry eye
12
livedo
12
lethargy
11
chest pain
11
bone pain
10
hemiplegia
10
hoarseness
10
respiratory distress
10
incoordination
9
neurological disability
9
Lhermitte's sign
8
blurred vision
8
agitation
7
apathy
7
more...
Drug
Bortezomib
136
Oxaliplatin
117
Taxol
84
Dermatol
70
CSF
67
vitamin E
43
Docetaxel
29
Pregabalin
26
AZT
24
AZT
24
Posture
24
ddI
21
Vitamin B
20
Domperidone
19
Duloxetine
19
G-CSF
16
Cardiovasc
15
Rituximab
15
Adriamycin
14
lysine
14
Gabapentin
14
CTX
13
Cremophor EL
13
Lenalidomide
13
Vitamin B12
12
pyridoxal phosphate
12
CPT-11
11
ADM
11
Vindesine
11
ascorbate
11
Vindesine
11
DM1
10
CTC
10
niacin
10
p75
10
CTC
10
Taxotere
10
Vinorelbine
9
Vitamin E
8
ROC
8
Leucovorin
8
Perhexiline maleate
7
ALA
7
Dial
7
Ixabepilone
6
Epalrestat
6
Ethanol
6
Isoniazid
6
ROS
6
Simvastatin
6
Asthma
5
CTX
5
PTH
5
Monit
5
CTX
5
Prednisone
5
Navelbine
5
Tapentadol
5
NADH
5
Infliximab
4
Herceptin
4
Bevacizumab
4
Alliance
4
Asn
4
Arsenic trioxide
4
Parkin
4
Miglustat
4
Infliximab
4
Tacrolimus
4
Fludarabine
4
Parkin
4
Phenytoin
4
HCG
4
ENT
3
ABC
3
Glutathione
3
Amifostine
3
Prednisolone
3
IFN-gamma
3
Gastro
3
more...
Enzyme
proteasome
91
reverse transcriptase
77
ERK
63
mitogen-activated protein kinase
54
aldose reductase
49
protein kinase C
42
creatine kinase
39
protein kinase
39
ATPase
35
focal adhesion kinase
32
thymidine phosphorylase
28
superoxide dismutase
28
peroxidase
23
caspase-3
21
catalase
18
acetylcholinesterase
17
DNA polymerase
16
ACS
16
alkaline phosphatase
15
alanine aminotransferase
14
kinesin
13
phosphodiesterase
13
PARP
13
pyruvate dehydrogenase
12
RNA polymerase
12
MEK
12
ACE
12
cytochrome oxidase
12
renin
12
CYP3A4
11
asparaginase
11
cholinesterase
11
aspartate aminotransferase
11
AMP-activated protein kinase
10
lactate dehydrogenase
10
transcriptase
9
3-hydroxyacyl-CoA dehydrogenase
9
transketolase
9
P-glycoprotein
9
CPT
9
SPT
9
AST
9
tyrosine hydroxylase
8
dihydropyrimidine dehydrogenase
8
complex I
8
porphobilinogen deaminase
8
CD10
7
arylsulfatase A
7
CPT
7
glutathione peroxidase
7
3-hydroxyacyl-CoA dehydrogenase
7
sulfatase
7
AMPK
7
PDK1
7
dihydropyrimidine dehydrogenase
6
glutathione S-transferase
6
endonuclease
6
CPT
6
lysozyme
6
NO synthase
6
luciferase
6
AMPK
6
ceruloplasmin
6
pyruvate dehydrogenase
6
pyruvate dehydrogenase
6
glycyl-tRNA synthetase
6
CYP27A1
6
BAL
6
succinate dehydrogenase
6
phosphatidylinositol 3-kinase
6
MDR
6
prostate-specific antigen
5
methylenetetrahydrofolate reductase
5
calcineurin
5
alpha-galactosidase
5
adenylate cyclase
5
15-lipoxygenase
5
ALA synthase
5
GSK
5
MTD
5
more...
Compound
Clin
973
Dec
732
glucose
364
DNA
324
Paclitaxel
184
calcium
173
creatinine
135
water
130
oxygen
128
sodium
127
DDP
95
Neo
83
TNF
77
His
74
ethanol
69
Vincristine
66
potassium
56
phosphate
51
NAD
49
d4T
48
glutamate
48
hexane
45
acrylamide
41
GM1
37
urea
37
nitric oxide
37
methionine
37
ATP
36
sulfate
36
nicotinamide
35
copper
35
zinc
35
2,5-hexanedione
33
serine
31
AZT
30
DPN
29
acetone
29
iron
28
5-FU
28
noradrenaline
27
arginine
26
Insulin
26
Docetaxel
26
Capsaicin
25
vitamin D
25
galactose
25
L-carnitine
24
tyrosine
24
Diabetol
24
acetate
24
Diabetol
24
mercury
23
tryptophan
23
homocysteine
23
nitrogen
23
STZ
22
threonine
22
NIDA
22
Neuronal
22
leucine
21
Arsenic
20
lysine
20
CBDCA
19
hydrogen
19
CBDCA
19
folinic acid
18
Cardiol
18
cysteine
18
GSH
17
Adriamycin
17
NMDA
17
GSH
17
ACS
16
Lead
16
Thiamine
16
ACS
16
GABA
15
NAD
15
GABA
15
proline
15
more...