Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0031117 (
peripheral neuropathy
)
10,577
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
axonal
979
Sep
665
insulin
381
Mol
244
She
168
GBS
164
MRI
156
hemoglobin
115
proteasome inhibitor
105
CD4
104
X-linked
98
proteasome
90
albumin
88
transthyretin
87
TNF
77
B12
76
nerve growth factor
73
cytokine
70
myelin-associated glycoprotein
70
IgA
69
Cx32
63
CSF
63
endoplasmic reticulum
61
interferon
55
tumor necrosis factor
51
aldose reductase
49
vascular endothelial growth factor
47
peripheral myelin protein 22
46
CMT1A
46
PMP22
46
calcitonin
41
myelin protein zero
40
glycoprotein
39
IL-6
39
collagen
39
chronic renal failure
37
ATP
36
substance P
36
caspase-3
35
membrane-bound
34
more...
Disease
peripheral neuropathy
10577
neuropathy
2482
diabetes
1563
cancer
1074
polyneuropathy
671
multiple myeloma
432
Charcot-Marie-Tooth disease
408
diabetic neuropathy
391
neutropenia
370
HIV
355
tumor
315
type 2 diabetes
309
vasculitis
294
thrombocytopenia
268
AIDS
263
retinopathy
259
anemia
236
hypertension
232
autonomic neuropathy
228
cold
225
sensory neuropathy
218
myopathy
206
renal disease
205
encephalopathy
204
breast cancer
191
dementia
183
amyloidosis
178
hyperglycemia
176
immunodeficiency
174
depression
162
stroke
152
lymphoma
148
myelopathy
143
carpal tunnel syndrome
138
chronic pain
136
type 1 diabetes
128
myelosuppression
127
cognitive impairment
121
cardiomyopathy
119
rash
116
more...
Symptom
pain
1449
weakness
547
ataxia
374
fatigue
243
diarrhea
237
numbness
224
seizures
201
nausea
197
vomiting
191
paresthesia
191
cerebellar ataxia
168
headache
140
tremor
115
nausea and vomiting
106
myalgia
102
constipation
97
ophthalmoplegia
93
abdominal pain
78
arthralgia
75
tingling
68
spasticity
63
sleepiness
62
paraparesis
60
anesthesia
59
Neuropathic pain
58
dysarthria
58
dizziness
56
anorexia
55
hypotonia
50
dystonia
47
dyspnea
46
analgesia
46
paresis
44
discomfort
43
asthenia
43
discomfort
37
splenomegaly
37
cachexia
36
hepatomegaly
36
dysesthesia
32
more...
Drug
Bortezomib
136
Oxaliplatin
117
Taxol
84
Dermatol
70
CSF
67
vitamin E
43
Docetaxel
29
Pregabalin
26
AZT
24
AZT
24
Posture
24
ddI
21
Vitamin B
20
Duloxetine
19
Domperidone
19
G-CSF
16
Cardiovasc
15
Rituximab
15
Gabapentin
14
lysine
14
Adriamycin
14
CTX
13
Lenalidomide
13
Cremophor EL
13
pyridoxal phosphate
12
Vitamin B12
12
Vindesine
11
Vindesine
11
ADM
11
CPT-11
11
ascorbate
11
CTC
10
DM1
10
niacin
10
p75
10
CTC
10
Taxotere
10
Vinorelbine
9
ROC
8
Vitamin E
8
more...
Enzyme
proteasome
91
reverse transcriptase
77
ERK
63
mitogen-activated protein kinase
54
aldose reductase
49
protein kinase C
42
protein kinase
39
creatine kinase
39
ATPase
35
focal adhesion kinase
32
superoxide dismutase
28
thymidine phosphorylase
28
peroxidase
23
caspase-3
21
catalase
18
acetylcholinesterase
17
DNA polymerase
16
ACS
16
alkaline phosphatase
15
alanine aminotransferase
14
phosphodiesterase
13
kinesin
13
PARP
13
pyruvate dehydrogenase
12
MEK
12
RNA polymerase
12
renin
12
cytochrome oxidase
12
ACE
12
CYP3A4
11
aspartate aminotransferase
11
asparaginase
11
cholinesterase
11
AMP-activated protein kinase
10
lactate dehydrogenase
10
CPT
9
AST
9
P-glycoprotein
9
SPT
9
transcriptase
9
more...
Compound
Clin
973
Dec
732
glucose
364
DNA
324
Paclitaxel
184
calcium
173
creatinine
135
water
130
oxygen
128
sodium
127
DDP
95
Neo
83
TNF
77
His
74
ethanol
69
Vincristine
66
potassium
56
phosphate
51
NAD
49
glutamate
48
d4T
48
hexane
45
acrylamide
41
urea
37
nitric oxide
37
GM1
37
methionine
37
ATP
36
sulfate
36
zinc
35
copper
35
nicotinamide
35
2,5-hexanedione
33
serine
31
AZT
30
DPN
29
acetone
29
5-FU
28
iron
28
noradrenaline
27
more...