Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0031117 (peripheral neuropathy)
10,577 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein axonal 979 Sep 665 insulin 381 Mol 244 She 168 GBS 164 MRI 156 hemoglobin 115 proteasome inhibitor 105 CD4 104 X-linked 98 proteasome 90 albumin 88 transthyretin 87 TNF 77 B12 76 nerve growth factor 73 myelin-associated glycoprotein 70 cytokine 70 IgA 69 Cx32 63 CSF 63 endoplasmic reticulum 61 interferon 55 tumor necrosis factor 51 aldose reductase 49 vascular endothelial growth factor 47 CMT1A 46 peripheral myelin protein 22 46 PMP22 46 calcitonin 41 myelin protein zero 40 IL-6 39 collagen 39 glycoprotein 39 chronic renal failure 37 substance P 36 ATP 36 caspase-3 35 membrane-bound 34 DRG 34 granulocyte colony-stimulating factor 31 M-protein 31 asymmetrical 31 lymphoid 31 CMT1 29 ATPase 29 gut 29 tRNA 28 p38 28 thymidine phosphorylase 28 non-Hodgkin's lymphoma 27 HER2 27 myelin basic protein 27 creatine kinase 27 HLA 26 sodium channel 25 nodal 25 Pol 25 ALD 25 MAG 24 p24 antigen 24 rheumatoid factor 24 glial fibrillary acidic protein 24 ubiquitin 24 calcium channel 24 superoxide dismutase 24 CMT2 23 neurotrophic factor 23 neurotrophin 23 cytochrome P450 23 CD8 22 TRPV1 22 granulocyte 22 CHOP 22 nitric oxide synthase 21 brain-derived neurotrophic factor 21 platelet-derived 21 Proteasome 21 interleukin-6 21 cytochrome c oxidase 20 long chain 20 NGF 20 PI3K 20 connexin 20 SACS 20 erythropoietin 19 MAPK 19 reductase 19 HDL 19 ERK 17 serum protein 17 C-reactive protein 17 GTPase 17 p53 17 IL-10 17 ankyrin 1 17 GSH 16 interferon-alpha 16 ERK1 16 catalase 16 myeloperoxidase 16 chemokine 16 MFN2 16 heat shock protein 16 Bcl-2 16 CD30 16 mTOR 16 ACS 16 G-CSF 15 IDDM 15 NAD 15 tyrosine kinase 15 olfactory 15 GABA 15 alkaline phosphatase 15 NMDA receptor 15 IFN 15 TNF-alpha 15 mitofusin 2 15 NIDDM 15 glucagon 14 erythroid 14 opioid receptor 14 KCC3 14 VEGF 14 IgE 14 MIM 13 CMT2A 13 HMSN I 13 TLR4 13 JNK 13 transient receptor potential vanilloid 1 13 ATTR 13 SCA3 13 POLG 13 DNA polymerase gamma 13 phosphodiesterase 13 kinesin 13 cage 13 DNA polymerase 13 phosphatase 13 NF-L 12 LITAF 12 membrane protein 12 PARP 12 p38 mitogen-activated protein kinase 12 gelsolin 12 renin 12 TTR 12 amyloid precursor protein 12 PKC 12 AKT 12 SOX10 11 SCA1 11 SCA2 11 epidermal growth factor receptor 11 prealbumin 11 HSPB1 11 Met 11 more...

Disease peripheral neuropathy 10577 neuropathy 2482 diabetes 1563 cancer 1074 polyneuropathy 671 multiple myeloma 432 Charcot-Marie-Tooth disease 408 diabetic neuropathy 391 neutropenia 370 HIV 355 tumor 315 type 2 diabetes 309 vasculitis 294 thrombocytopenia 268 AIDS 263 retinopathy 259 anemia 236 hypertension 232 autonomic neuropathy 228 cold 225 sensory neuropathy 218 myopathy 206 renal disease 205 encephalopathy 204 breast cancer 191 dementia 183 amyloidosis 178 hyperglycemia 176 immunodeficiency 174 depression 162 stroke 152 lymphoma 148 myelopathy 143 carpal tunnel syndrome 138 chronic pain 136 type 1 diabetes 128 myelosuppression 127 cognitive impairment 121 cardiomyopathy 119 rash 116 colorectal cancer 113 leukopenia 111 multiple sclerosis 110 leprosy 110 gammopathy 109 muscular atrophy 108 neurological disease 106 obesity 104 systemic lupus erythematosus 103 Frey 100 peripheral vascular disease 100 renal failure 97 cryoglobulinemia 96 mononeuropathy 94 metastases 93 carcinoma 91 POEMS syndrome 90 epilepsy 89 ovarian cancer 87 ischemia 87 non-small cell lung cancer 85 Parkinson's disease 84 Hodgkin's disease 84 deafness 84 proteinuria 82 rheumatoid arthritis 81 metastatic breast cancer 80 malnutrition 79 parkinsonism 75 hypoglycemia 74 leukemia 73 heart failure 72 alcoholism 71 arthritis 71 leukoencephalopathy 69 lactic acidosis 69 sepsis 69 mononeuritis 68 mental retardation 67 mental retardation 67 optic atrophy 67 hepatitis C 65 lung cancer 65 diabetic retinopathy 64 tuberculosis 64 purpura 63 pancreatitis 63 infectious diseases 61 sepsis 61 macroglobulinemia 61 dysplasia 61 pneumonia 60 vascular disease 60 amyotrophic lateral sclerosis 59 asthma 58 encephalitis 57 postherpetic neuralgia 57 radiculopathy 57 lupus 56 polyradiculoneuropathy 56 lymphadenopathy 55 hypothyroidism 55 cardiovascular disease 55 cytomegalovirus 54 diabetic nephropathy 54 psychosis 54 polyarteritis nodosa 53 eosinophilia 53 Alzheimer's disease 53 Churg-Strauss syndrome 52 monoclonal gammopathy of undetermined significance 52 prolapse 51 Diabetic foot 50 spastic paraplegia 50 autoimmune disease 50 osteomyelitis 49 hepatitis 49 adenocarcinoma 49 gastric cancer 49 vitamin B12 deficiency 47 acute lymphoblastic leukemia 47 celiac disease 47 diabetic foot ulcers 47 chronic renal failure 46 glucose intolerance 46 glomerulonephritis 46 coma 44 nystagmus 44 Diabetic peripheral neuropathy 43 gangrene 42 virus infection 42 cirrhosis 42 lupus 42 liver disease 42 impotence 42 myelitis 42 sarcoidosis 42 deep vein thrombosis 41 systemic disease 41 ARC 41 Diabetic neuropathy 41 hereditary motor and sensory neuropathy 41 Mycobacterium 41 neuritis 40 CMT1A 40 blindness 40 hyperlipidemia 39 epithelial ovarian cancer 38 Crohn's disease 38 meningitis 37 osteoporosis 37 melanoma 37 fits 37 respiratory failure 36 renal insufficiency 35 microalbuminuria 35 myocardial infarction 35 atherosclerosis 35 congestive heart failure 35 cataract 35 more...

Symptom pain 1449 weakness 547 ataxia 374 fatigue 243 diarrhea 237 numbness 224 seizures 201 nausea 197 paresthesia 191 vomiting 191 cerebellar ataxia 168 headache 140 tremor 115 nausea and vomiting 106 myalgia 102 constipation 97 ophthalmoplegia 93 abdominal pain 78 arthralgia 75 tingling 68 spasticity 63 sleepiness 62 paraparesis 60 anesthesia 59 dysarthria 58 Neuropathic pain 58 dizziness 56 anorexia 55 hypotonia 50 dystonia 47 analgesia 46 dyspnea 46 paresis 44 discomfort 43 asthenia 43 splenomegaly 37 discomfort 37 hepatomegaly 36 cachexia 36 dysesthesia 32 insomnia 31 hepatosplenomegaly 30 Ill 29 back pain 28 chorea 28 myoclonus 27 erythema 25 acute pain 23 cough 22 angina 21 ataxic gait 19 cancer pain 18 neuralgia 17 low back pain 16 memory loss 16 thinning 16 abnormal gait 16 fasciculation 15 collapse 14 functional recovery 14 overweight 14 vertigo 13 tinnitus 13 syncope 12 muscle cramps 12 intention tremor 12 livedo 12 dry eye 12 lethargy 11 chest pain 11 hemiplegia 10 hoarseness 10 respiratory distress 10 bone pain 10 neurological disability 9 incoordination 9 Lhermitte's sign 8 blurred vision 8 sore throat 7 apathy 7 hyperesthesia 7 shortness of breath 7 leg pain 7 agitation 7 night sweats 7 limb pain 6 exertional dyspnea 6 pallor 6 polyuria 6 spasm 6 neck pain 6 Gastrointestinal symptoms 6 chills 6 asterixis 6 bradykinesia 5 loss of balance 5 shoulder pain 5 stigma 5 clubbing 5 starvation 5 Neurologic symptoms 5 anosmia 5 Depressive symptoms 5 hypercapnia 5 orthopnea 5 hypertonia 5 polydipsia 5 consciousness disturbance 5 flushing 5 pelvic pain 4 decreased appetite 4 Sensory ataxia 4 Signs and Symptoms 4 hemoptysis 4 forgetfulness 4 stridor 4 hypothermia 4 Myokymia 4 dysuria 4 skin irritation 4 muscle stiffness 4 knee pain 3 giddiness 3 heartburn 3 ENT 3 abdominal discomfort 3 leg edema 3 nerve pain 3 hypoproteinemia 3 inanition 3 Livedoid 3 leg cramps 3 Burning 3 bloating 3 Excitability 3 thigh pain 3 regurgitation 3 tense 3 polymyalgia 3 testicular pain 3 acute abdominal pain 2 neck stiffness 2 Cold intolerance 2 twitching 2 giddiness 2 breakthrough pain 2 sciatica 2 excessive sweating 2 chronic back pain 2 prostration 2 catatonia 2 jaundice of the skin 2 abdominal fullness 2 hip pain 2 Fear of falling 2 Mechanical pain 2 hyperemesis gravidarum 2 GI irritation 2 Trepopnea 2 exhaustion 2 more...

Drug Bortezomib 136 Oxaliplatin 117 Taxol 84 Dermatol 70 CSF 67 vitamin E 43 Docetaxel 29 Pregabalin 26 AZT 24 Posture 24 AZT 24 ddI 21 Vitamin B 20 Domperidone 19 Duloxetine 19 G-CSF 16 Cardiovasc 15 Rituximab 15 Gabapentin 14 lysine 14 Adriamycin 14 CTX 13 Lenalidomide 13 Cremophor EL 13 pyridoxal phosphate 12 Vitamin B12 12 ADM 11 Vindesine 11 CPT-11 11 ascorbate 11 Vindesine 11 Taxotere 10 p75 10 CTC 10 DM1 10 niacin 10 CTC 10 Vinorelbine 9 Vitamin E 8 ROC 8 Leucovorin 8 Perhexiline maleate 7 ALA 7 Dial 7 Ethanol 6 Ixabepilone 6 Epalrestat 6 ROS 6 Isoniazid 6 Simvastatin 6 CTX 5 CTX 5 Asthma 5 Monit 5 NADH 5 PTH 5 Prednisone 5 Tapentadol 5 Navelbine 5 Asn 4 Parkin 4 Fludarabine 4 Tacrolimus 4 Herceptin 4 Infliximab 4 Bevacizumab 4 Infliximab 4 Miglustat 4 Parkin 4 Phenytoin 4 Arsenic trioxide 4 HCG 4 Alliance 4 Amifostine 3 Glutathione 3 ABC 3 DHT 3 ENT 3 Nelarabine 3 Prednisolone 3 Riboflavin 3 Gastro 3 IFN-gamma 3 MRC 3 MAP 3 Ddc 3 Nephron 3 Perhexiline 2 Etoposide 2 Gefitinib 2 Ipilimumab 2 Benfotiamine 2 Rifaximin 2 Aztec 2 Irinotecan 2 Cidofovir 2 VCR 2 Dakar 2 NAH 2 Clinoril 2 Leaf 2 Albumin 2 EPI 2 Vicryl 2 Lipoic Acid 2 Itraconazole 2 BLM 2 Serum albumin 2 Lafutidine 2 Gelatin 2 Dasatinib 2 Filgrastim 2 Paraffin 2 PDGF B-chain 2 AraC 2 Amiloride 2 Histamine 2 Fluorescein 2 Tanespimycin 2 Fluorescein 2 Filgrastim 2 PFT 2 Spectrum 2 Sinemet 2 Ganciclovir 2 Zoledronic acid 2 Zoledronic acid 2 Teniposide 2 Clonidine 2 TTC 2 VCR 2 Norplant 1 Zenarestat 1 Etodolac 1 Pefloxacin 1 Indomethacin 1 CVA 1 Myricetin 1 IPD 1 CIA 1 Methylprednisolone 1 Reboxetine 1 GEO 1 Vitamin K 1 Azithromycin 1 Acamprosate 1 MDS 1 Cimetidine 1 Xeloda 1 citric acid 1 9-THC 1 CFT 1 Campath 1 CPM 1 Trental 1 Sinemet 1 Modafinil 1 Succinic Acid 1 Paraplatin 1 SNL 1 more...

Enzyme proteasome 91 reverse transcriptase 77 ERK 63 mitogen-activated protein kinase 54 aldose reductase 49 protein kinase C 42 protein kinase 39 creatine kinase 39 ATPase 35 focal adhesion kinase 32 superoxide dismutase 28 thymidine phosphorylase 28 peroxidase 23 caspase-3 21 catalase 18 acetylcholinesterase 17 ACS 16 DNA polymerase 16 alkaline phosphatase 15 alanine aminotransferase 14 kinesin 13 PARP 13 phosphodiesterase 13 MEK 12 ACE 12 cytochrome oxidase 12 pyruvate dehydrogenase 12 renin 12 RNA polymerase 12 aspartate aminotransferase 11 CYP3A4 11 asparaginase 11 cholinesterase 11 lactate dehydrogenase 10 AMP-activated protein kinase 10 P-glycoprotein 9 transketolase 9 AST 9 SPT 9 CPT 9 transcriptase 9 3-hydroxyacyl-CoA dehydrogenase 9 tyrosine hydroxylase 8 dihydropyrimidine dehydrogenase 8 porphobilinogen deaminase 8 complex I 8 3-hydroxyacyl-CoA dehydrogenase 7 AMPK 7 CD10 7 glutathione peroxidase 7 PDK1 7 sulfatase 7 arylsulfatase A 7 CPT 7 endonuclease 6 dihydropyrimidine dehydrogenase 6 succinate dehydrogenase 6 AMPK 6 CPT 6 glycyl-tRNA synthetase 6 CYP27A1 6 MDR 6 phosphatidylinositol 3-kinase 6 luciferase 6 BAL 6 pyruvate dehydrogenase 6 lysozyme 6 glutathione S-transferase 6 ceruloplasmin 6 pyruvate dehydrogenase 6 NO synthase 6 calcineurin 5 15-lipoxygenase 5 methylenetetrahydrofolate reductase 5 alpha-galactosidase 5 adenylate cyclase 5 NADPH oxidase 5 ALA synthase 5 MTD 5 GSK 5 methylenetetrahydrofolate reductase 5 lipase 5 prostate-specific antigen 5 squalene epoxidase 4 thymidine kinase 4 CEP 4 phospholipase C 4 hexosaminidase 4 NADPH oxidase 4 Alternating 4 acyl-CoA dehydrogenase 4 galactocerebrosidase 4 PAL 4 neuropathy target esterase 4 thromboplastin 4 ATP synthase 4 CEP 4 alanyl-tRNA synthetase 4 gamma-glutamyl transpeptidase 4 NQO1 3 glyceraldehyde-3-phosphate dehydrogenase 3 N-acetylglucosaminyltransferase II 3 beta-glucuronidase 3 alcohol dehydrogenase 3 methionine synthase 3 aldehyde dehydrogenase 3 prostate-specific membrane antigen 3 cholesterol acyltransferase 3 methionine synthase 3 transglutaminase 3 glyceraldehyde-3-phosphate dehydrogenase 3 phosphatidate phosphatase 3 glyceraldehyde-3-phosphate dehydrogenase 3 UDP-glucuronosyltransferase 3 aldolase 3 thrombin 3 caspase-9 3 aldehyde dehydrogenase 3 NOS 3 aldehyde dehydrogenase 3 aldehyde dehydrogenase 3 glyceraldehyde-3-phosphate dehydrogenase 3 aldehyde dehydrogenase 3 phospholipase A2 3 histidyl-tRNA synthetase 3 pantothenate kinase 3 matrix metalloproteinase 2 3 citrate synthase 3 caspase-1 3 phytanoyl-CoA hydroxylase 3 glutathione reductase 3 prolyl hydroxylase 3 lipoprotein lipase 3 glyceraldehyde-3-phosphate dehydrogenase 3 thymidylate synthase 3 heme oxygenase 2 granzyme B 2 fumarylacetoacetate hydrolase 2 glucose-6-phosphate dehydrogenase 2 branching enzyme 2 PDE 2 urease 2 pyruvate decarboxylase 2 glucosylceramide synthase 2 urease 2 peroxiredoxin 2 choline acetyltransferase 2 PRPP synthetase 2 acid phosphatase 2 nicotinamide phosphoribosyltransferase 2 hyaluronidase 2 enolase 2 pepsin 2 arylsulfatase 2 ECH 2 Thy1 2 beta-galactosidase 2 topoisomerase 2 IKK 2 PKG 2 more...

Compound Clin 973 Dec 732 glucose 364 DNA 324 Paclitaxel 184 calcium 173 creatinine 135 water 130 oxygen 128 sodium 127 DDP 95 Neo 83 TNF 77 His 74 ethanol 69 Vincristine 66 potassium 56 phosphate 51 NAD 49 glutamate 48 d4T 48 hexane 45 acrylamide 41 GM1 37 urea 37 methionine 37 nitric oxide 37 ATP 36 sulfate 36 zinc 35 nicotinamide 35 copper 35 2,5-hexanedione 33 serine 31 AZT 30 DPN 29 acetone 29 iron 28 5-FU 28 noradrenaline 27 Insulin 26 Docetaxel 26 arginine 26 Capsaicin 25 vitamin D 25 galactose 25 Diabetol 24 L-carnitine 24 acetate 24 tyrosine 24 Diabetol 24 homocysteine 23 mercury 23 tryptophan 23 nitrogen 23 Neuronal 22 threonine 22 STZ 22 NIDA 22 leucine 21 lysine 20 Arsenic 20 CBDCA 19 CBDCA 19 hydrogen 19 Cardiol 18 folinic acid 18 cysteine 18 GSH 17 NMDA 17 GSH 17 Adriamycin 17 ACS 16 Lead 16 Thiamine 16 ACS 16 GABA 15 alanine 15 glutamine 15 GABA 15 proline 15 NAD 15 TTS 14 Optimal 14 Misonidazole 14 cobalt 13 toluene 13 nicotinic acid 13 INH 13 manganese 13 salt 13 CO2 13 CTX 13 cAMP 13 MEK 13 chromium 12 Linezolid 12 valine 12 oxalate 12 tryptophan 12 N-acetylcysteine 12 Dichloroacetate 12 tryptophan 12 tryptophan 12 ADP 12 Pyridoxine 11 Didanosine 11 silver 11 3TC 11 CoA 11 CPT-11 11 ADP 10 Pac 10 alloxan 10 Capecitabine 10 5-HT 10 ANCA 10 Congo red 10 FK506 10 ADP 10 Acetyl-L-carnitine 9 MDA 9 VP-16 9 gamma-aminobutyric acid 9 3-Deazaneplanocin 9 prostaglandin E1 9 Ara-C 9 aldosterone 9 Glutamate 8 ACTH 8 cyanide 8 GD3 8 phosphorus 8 Adrenal 8 A 1 8 Metformin 8 CAM 8 Dial 8 glutamic acid 8 aluminum 8 Metformin 8 Vitamin E 8 BCNU 8 bromide 8 coenzyme Q10 7 CAP 7 retinoic acid 7 uridine 7 acetic acid 7 L-DOPA 7 Amiodarone 7 GM2 7 Mg2+ 7 NADPH 7 ammonia 7 FAP 7 BAL 7 MTT 7 NADPH 7 Ile 7 more...

---