Gene/Protein
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Enzyme
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Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0031117 (
peripheral neuropathy
)
10,577
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We report the case of a 46-day-old boy with a fulminant vincristine-induced
peripheral neuropathy
after treatment for congenital acute lymphoblastic leukemia.
Flaccid paralysis
developed at the end of the first phase of induction, requiring intubation and ventilation for 51 days. Treatment was initiated with levocarnitine, N-acetylcysteine, and pyridoxine and progressive reversal of the neuropathy occurred over the next 4 months. Potential differences in pathogenesis and presentation of vincristine neurotoxicity and Guillian-Barre syndrome in the neonate are discussed.
...
PMID:Vincristine-induced peripheral neuropathy in a neonate with congenital acute lymphoblastic leukemia. 2021 33
