Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0031099 (periodontitis)
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Human Gene/Protein
Periodontal ligament-associated protein 1 11.3
Fc-gamma receptor IIIb 11.3
glycosyltransferase 6 domain containing 1 11.3
ZNF57 10.3
chondroitinsulfatase 10.3
TTLL11 10.3
Apoptotic peptidase activating factor 1 10.3
ZNF675 10.3
GCF 9.8
chemokine receptor-like 1 9.7
HSP90BB 9.7
Proline aminopeptidase 9.7
ABHD12B 9.7
ZNF823 9.7
RGP2 9.7
JP2 9.5
Gp110 9.3
EMD protein 9.3
GPR141 9.3
Radioprotective 105 kDa protein 9.3
GP110 9.3
CTSC 9.1
Sphingomyelin phosphodiesterase 3 9.0
EEIG1 9.0
FBXO38 9.0
SIGLEC5 8.9
Cytoskeleton-associated protein 2-like 8.7
tripartite motif-containing 22 8.7
MFSD1 8.7
CSRP 8.5
putative tyrosine phosphatase 8.5
CAPN8 8.5
transposase-like protein 8.5
cathepsin C 8.4
BEGAIN 8.3
T-cell protein-tyrosine phosphatase 8.3
paraoxonase 3 8.3
AP3B2 8.2
RagB 8.2
ZNF215 8.1
more...
Disease
Reversible pulpitis 11.3
Phoenix abscess 11.3
periodontitis 11.3
Gingival and periodontal diseases 11.3
Attachment Loss, Periodontal 11.3
Refractory periodontitis 11.1
Linear gingival erythema 11.0
Rapidly progressive periodontitis 10.9
Adult periodontitis 10.8
Subgingival plaque 10.7
Apical periodontitis 10.7
Persistent deciduous teeth 10.6
Chronic apical periodontitis 10.6
Marginal periodontitis 10.5
Acute gingivitis 10.3
Ehlers-Danlos syndrome type VIII 10.3
Chronic apical abscess 10.3
juvenile periodontitis 10.3
Alveolar bone loss 10.1
ANUG 9.9
gingivitis 9.8
Ulcerative stomatitis 9.7
periodontal disease 9.5
dental deposit 9.5
Periodontal infection 9.4
periodontosis 9.4
GEY 9.3
Early onset periodontitis 9.3
Psoriasiform dermatitis 9.3
Periapical disease 9.3
Inability to understand 9.3
tooth loss 9.3
Irreversible pulpitis 9.1
gum disease 9.1
Periapical abscesses 9.0
pulpitis 8.9
Deep caries 8.7
Pseudomembranous candidiasis 8.7
pericoronitis 8.7
pyorrhea 8.7
more...
Symptom
pain in the gums 11.3
temporomandibular joint problem 9.7
Sulfur granules 9.0
Premature loss of teeth 8.7
Burning mouth 8.0
halitosis 7.9
prickling sensation 7.4
ischuria 6.6
enanthema 6.6
Mechanical pain 6.3
hyperosmia 6.2
dental pain 5.7
microbial colonization 5.1
disturbed balance 5.1
scaly skin 4.9
No pain 4.5
Severe pain 4.0
hyperesthesia 3.9
pachyonychia 3.8
loss of taste 3.8
Postoperative pain 3.6
orofacial pain 3.4
swollen joints 3.3
No adverse effect 3.0
Tenderness 2.8
erythema 2.5
loss of balance 2.5
stomach pain 2.4
Decreased activity 2.3
ketonuria 2.2
adenitis 2.2
discomfort 2.1
excessive sweating 2.1
Fluctuation 2.1
discomfort 2.1
tachypnea 1.6
neuralgia 1.6
ENT 1.5
muscle cramps 1.5
sore throat 1.5
more...
Drug
DOXY 9.2
Clavamox 9.0
Vibramycin 8.7
Dichlorophenamide 8.5
Cleocin 8.1
Minocin 8.1
Alendronate sodium 7.7
Maxacalcitol 7.1
Meclomen 6.7
Lumiracoxib 6.7
Cinnamon bark 6.7
Augmentin 6.6
Miocamycin 6.6
Augmentin 6.5
Tantum 6.5
Iodipamide 6.5
MINO 6.4
Emla 6.4
Sitafloxacin 6.4
Meclomen 6.3
Unasyn 6.3
PDL 6.3
Belladonna 6.3
Dalacin 6.1
CZON 6.1
Tinidazole 5.8
Peridex 5.8
SnF2 5.7
Calcium gluconate 5.7
Ethylcellulose 5.7
Aredia 5.7
Sodium hypochlorite 5.7
Dilantin 5.6
Ketorolac tromethamine 5.5
Peridex 5.5
Doxycycline 5.5
Zaditen 5.5
Butaprost 5.4
Midostaurin 5.3
Esculin 5.3
more...
Enzyme
chondroitinsulfatase 10.3
Lys-gingipain 10.0
RGP 9.1
EC 2.8.3.9 9.0
cathepsin C 8.1
neutrophil collagenase 7.8
mycothione reductase 7.7
peptidylarginine deiminase 7.4
hydroxylamine reductase 7.3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7.3
hydroxylamine reductase 7.3
CbiX 6.9
N-acetylglucosamine-6-sulfatase 6.7
phosphoamidase 6.0
acetylornithine aminotransferase 6.0
cathepsin K 6.0
methylglyoxal synthase 5.6
KLK13 5.6
arginine deiminase 5.6
LuxS 5.4
cathepsin V 5.3
collagenase 3 5.3
proline iminopeptidase 5.3
phosphoenolpyruvate synthase 5.3
cyanase 5.3
nicotinamide phosphoribosyltransferase 5.1
cystathionine gamma-lyase 5.1
collagenase 4.9
IgA1 protease 4.8
cathepsin G 4.8
MMP-3 4.7
Hageman factor 4.6
neutrophil elastase 4.6
interstitial collagenase 4.4
penicillopepsin 4.4
lysyl hydroxylase 4.4
IgA protease 4.4
glycyl-tRNA synthetase 4.4
NADH peroxidase 4.3
elastase 4.3
more...
Compound
1-chloroisoquinoline 10.3
N-Phenylmaleimide 9.0
2,4,8,10-tetraoxaspiro[5.5]undecane 8.7
Fentiazac 8.3
N-Phenylmaleimide 8.3
Clindamycin hydrochloride 8.1
New Methylene Blue 8.1
Plantamajoside 8.0
Clindamycin hydrochloride 8.0
DuP 697 7.7
Resolvin D2 7.7
Tetracycline hydrochloride 7.7
No. 118 7.6
Kavain 7.4
SP-G 7.1
1,2,6-hexanetriol 7.1
Calcium hydroxide 7.1
TBO 7.1
Dehydrocostus lactone 7.1
Zwittergent 3-14 7.0
Angelicin 6.9
Thiolactomycin 6.9
Stachydrine 6.8
PD 5 6.7
BOP 6.6
Spiramycin 6.6
Ornidazole 6.5
1,10-decanediol 6.5
Spiramycin 6.5
Josamycin 6.5
Tamibarotene 6.5
Phenidone 6.5
Acetylshikonin 6.5
Josamycin 6.4
Josamycin 6.4
Sitafloxacin 6.4
Z-Gly 6.4
Cryptoxanthin 6.3
Plastoquinone 6.3
GDP-4-keto-6-deoxy-D-mannose 6.3
more...