Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0031099 (
periodontitis
)
12,489
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
766
cytokine
590
lipopolysaccharide
492
Mol
393
IL-6
389
collagen
362
TNF
348
IL-8
250
RANKL
241
tumor necrosis factor
212
LPS
174
IL-1
160
osteogenic
153
IL-10
152
TLR4
148
insulin
143
IgA
137
TLR2
132
alkaline phosphatase
116
C-reactive protein
113
matrix metalloproteinase
113
interleukin-6
112
CD4
111
collagenase
108
IL-17
108
osteoprotegerin
107
IL-1 beta
101
p38
90
tumor necrosis factor alpha
90
TNF-alpha
87
Cytokine
87
IL-4
85
hemoglobin
82
MMP-8
81
MMP-9
81
chemokine
76
IFN
72
kit
69
tartrate-resistant acid phosphatase
68
SDS
67
more...
Disease
periodontitis
12489
periodontal disease
2404
plaque
1846
gingivitis
1283
diabetes
662
tooth loss
525
rheumatoid arthritis
344
dental caries
325
juvenile periodontitis
297
infectious diseases
267
cardiovascular disease
232
cancer
214
atherosclerosis
214
osteoporosis
209
Plaque
188
type 2 diabetes
161
HIV
152
obesity
149
bacterial infection
137
Subgingival plaque
132
pulpitis
119
systemic disease
105
edentulous
103
arthritis
102
hypertension
102
stroke
93
Alzheimer's disease
81
immunodeficiency
77
AIDS
76
tumor
75
endocarditis
70
coronary heart disease
69
oral cancer
69
bacteremia
68
SDS
68
aggression
65
hyperkeratosis
63
metabolic syndrome
59
osteomyelitis
56
hyperglycemia
53
more...
Symptom
pain
229
anesthesia
73
halitosis
54
discomfort
40
discomfort
39
erythema
30
dental pain
25
diarrhea
17
overweight
17
microbial colonization
14
angina
9
anorexia
8
fatigue
8
headache
7
distraction
7
weakness
6
ENT
6
arthralgia
6
analgesia
5
paresthesia
5
Ill
5
numbness
5
Postoperative pain
5
collapse
4
respiratory distress
4
chest pain
4
orofacial pain
4
thinning
4
cachexia
3
splenomegaly
3
regurgitation
3
disturbed balance
3
back pain
3
vomiting
3
insomnia
3
sore throat
3
agitation
3
acidity
3
hyperesthesia
3
tachypnea
3
more...
Drug
lysine
66
Dermatol
47
IFN-gamma
46
IL-2
42
citric acid
24
ascorbate
23
IL-1ra
20
PDL
20
Doxycycline
19
Gel
18
ROS
18
ampicillin
17
CSF
17
Amoxicillin
14
Azithromycin
14
Monit
13
Vibramycin
12
DOXY
12
TTC
12
Cardiovasc
12
Bifidobacterium
11
AMC
11
Augmentin
10
Augmentin
10
vitamin E
10
CAM
9
Heme
9
lactose
9
Simvastatin
9
ENT
8
Asthma
8
OMP
7
ABC
7
ROC
7
TAC
7
IL-11
6
CaCl2
6
CaCl2
6
CTX
6
CaCl2
6
more...
Enzyme
collagenase
220
mitogen-activated protein kinase
180
alkaline phosphatase
117
peroxidase
90
trypsin
77
elastase
70
ERK
63
RGP
48
cathepsin K
46
catalase
44
superoxide dismutase
44
cathepsin C
42
Lys-gingipain
42
aspartate aminotransferase
41
neutrophil elastase
39
MMP-3
36
lactate dehydrogenase
35
acid phosphatase
34
beta-glucuronidase
33
focal adhesion kinase
29
caspase-1
28
caspase-3
26
lysozyme
25
protein kinase
25
peptidylarginine deiminase
23
luciferase
23
reverse transcriptase
23
beta-lactamase
22
neuraminidase
21
MMP
21
cathepsin G
20
cathepsin B
20
plasmin
18
endonuclease
18
neutrophil collagenase
17
proteinase K
16
phospholipase C
16
arginine deiminase
16
tryptase
15
kallikrein
15
more...
Compound
Clin
1300
Dec
849
DNA
625
TNF
348
calcium
282
oxygen
221
arginine
183
water
158
cysteine
157
glucose
153
sodium
137
phosphate
118
lysine
117
hydroxide
86
iron
84
SDS
72
acetate
69
nitric oxide
67
THP
65
THP
65
zinc
63
titanium
59
PGE
57
ClO
54
serine
54
sulfate
51
hydrogen
50
PGE2
50
His
45
alanine
44
NIDA
42
leucine
41
vitamin D
39
silver
37
MIC
37
iodine
36
Phe
34
ethanol
34
nitrogen
31
ALP
29
more...