Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0031099 (periodontitis)
12,489 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 766
cytokine 590
lipopolysaccharide 492
Mol 393
IL-6 389
collagen 362
TNF 348
IL-8 250
RANKL 241
tumor necrosis factor 212
LPS 174
IL-1 160
osteogenic 153
IL-10 152
TLR4 148
insulin 143
IgA 137
TLR2 132
alkaline phosphatase 116
C-reactive protein 113
matrix metalloproteinase 113
interleukin-6 112
CD4 111
collagenase 108
IL-17 108
osteoprotegerin 107
IL-1 beta 101
p38 90
tumor necrosis factor alpha 90
TNF-alpha 87
Cytokine 87
IL-4 85
hemoglobin 82
MMP-8 81
MMP-9 81
chemokine 76
IFN 72
kit 69
tartrate-resistant acid phosphatase 68
SDS 67
more...
Disease
periodontitis 12489
periodontal disease 2404
plaque 1846
gingivitis 1283
diabetes 662
tooth loss 525
rheumatoid arthritis 344
dental caries 325
juvenile periodontitis 297
infectious diseases 267
cardiovascular disease 232
cancer 214
atherosclerosis 214
osteoporosis 209
Plaque 188
type 2 diabetes 161
HIV 152
obesity 149
bacterial infection 137
Subgingival plaque 132
pulpitis 119
systemic disease 105
edentulous 103
arthritis 102
hypertension 102
stroke 93
Alzheimer's disease 81
immunodeficiency 77
AIDS 76
tumor 75
endocarditis 70
coronary heart disease 69
oral cancer 69
bacteremia 68
SDS 68
aggression 65
hyperkeratosis 63
metabolic syndrome 59
osteomyelitis 56
hyperglycemia 53
more...
Symptom
pain 229
anesthesia 73
halitosis 54
discomfort 40
discomfort 39
erythema 30
dental pain 25
diarrhea 17
overweight 17
microbial colonization 14
angina 9
anorexia 8
fatigue 8
headache 7
distraction 7
weakness 6
ENT 6
arthralgia 6
analgesia 5
paresthesia 5
Ill 5
numbness 5
Postoperative pain 5
collapse 4
respiratory distress 4
chest pain 4
orofacial pain 4
thinning 4
cachexia 3
splenomegaly 3
regurgitation 3
disturbed balance 3
back pain 3
vomiting 3
insomnia 3
sore throat 3
agitation 3
acidity 3
hyperesthesia 3
tachypnea 3
more...
Drug
lysine 66
Dermatol 47
IFN-gamma 46
IL-2 42
citric acid 24
ascorbate 23
IL-1ra 20
PDL 20
Doxycycline 19
Gel 18
ROS 18
ampicillin 17
CSF 17
Amoxicillin 14
Azithromycin 14
Monit 13
Vibramycin 12
DOXY 12
TTC 12
Cardiovasc 12
Bifidobacterium 11
AMC 11
Augmentin 10
Augmentin 10
vitamin E 10
CAM 9
Heme 9
lactose 9
Simvastatin 9
ENT 8
Asthma 8
OMP 7
ABC 7
ROC 7
TAC 7
IL-11 6
CaCl2 6
CaCl2 6
CTX 6
CaCl2 6
more...
Enzyme
collagenase 220
mitogen-activated protein kinase 180
alkaline phosphatase 117
peroxidase 90
trypsin 77
elastase 70
ERK 63
RGP 48
cathepsin K 46
catalase 44
superoxide dismutase 44
cathepsin C 42
Lys-gingipain 42
aspartate aminotransferase 41
neutrophil elastase 39
MMP-3 36
lactate dehydrogenase 35
acid phosphatase 34
beta-glucuronidase 33
focal adhesion kinase 29
caspase-1 28
caspase-3 26
lysozyme 25
protein kinase 25
peptidylarginine deiminase 23
luciferase 23
reverse transcriptase 23
beta-lactamase 22
neuraminidase 21
MMP 21
cathepsin G 20
cathepsin B 20
plasmin 18
endonuclease 18
neutrophil collagenase 17
proteinase K 16
phospholipase C 16
arginine deiminase 16
tryptase 15
kallikrein 15
more...
Compound
Clin 1300
Dec 849
DNA 625
TNF 348
calcium 282
oxygen 221
arginine 183
water 158
cysteine 157
glucose 153
sodium 137
phosphate 118
lysine 117
hydroxide 86
iron 84
SDS 72
acetate 69
nitric oxide 67
THP 65
THP 65
zinc 63
titanium 59
PGE 57
ClO 54
serine 54
sulfate 51
hydrogen 50
PGE2 50
His 45
alanine 44
NIDA 42
leucine 41
vitamin D 39
silver 37
MIC 37
iodine 36
Phe 34
ethanol 34
nitrogen 31
ALP 29
more...