Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0031099 (periodontitis)
12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The traditional model that teeth are lost due to caries early in life and periodontitis later has been challenged by recent studies. Randomly selected Air Force records were reviewed for the reasons for extractions. Between the ages of 20 to 50, the rate of loss due to caries declined from 0.11 to 0.03, whereas the rate due to periodontitis increased from 0 to 0.34. This study supported the traditional model that tooth loss due to caries decreases with age and that periodontitis is the major cause of loss later in life.
Mil Med 1995 Apr
PMID:Tooth loss during compulsory dental care. 761 29

An experimental periodontal screening examination and index was used to measure the prevalence of gingivitis and periodontitis among 1,334 soldiers at Fort Knox, Kentucky. Although 12.1% of the subjects demonstrated no disease, 40.3% were found to have gingivitis. In this sample group, the occurrence of gingivitis decreased with increasing age. Early periodontitis (probing depths of 3-5 mm) was detected in 35.7% of the subjects, and subjects with moderate to advanced periodontitis (probing depths greater than 5 mm) comprised 11.9% of the sample. The screening exam used is suggested for use as part of each soldier's annual dental examination.
Mil Med 1994 Mar
PMID:Prevalence of periodontal disease in an active duty military population as indicated by an experimental periodontal index. 804 72

Acute necrotizing ulcerative gingivitis-periodontitis (ANUG/NUP) is a relatively uncommon periodontal disease characterized by gingival necrosis and ulceration, pain, and bleeding. The purpose of this paper is to provide a review of current knowledge on ANUG/NUP. Current literature on the epidemiology, pathogenesis, immunology, predisposing factors, and treatment of ANUG/NUP is reviewed.
Mil Med 1998 May
PMID:Acute necrotizing ulcerative gingivitis-periodontitis: a literature review. 959 52

Early-onset periodontal diseases are often diagnosed in the military as a result of the requirements for annual dental examinations and the youthful population served. A young soldier diagnosed with rapidly progressive periodontitis completed initial therapy of root planing with the systemic antibiotic doxycycline but was poorly compliant with additional treatment. During a subsequent mandatory dental examination, new radiographs demonstrated a significant improvement in the quantity and quality of alveolar bone, illustrating the regeneration potential of the young patient with early-onset periodontal disease.
Mil Med 2000 Oct
PMID:Radiographic osseous regeneration after initial therapy with systemic doxycycline. 1105 Aug 79

Periodontal diseases are oral disorders characterized by inflammation of the supporting tissues of the teeth. Usually, periodontitis is a progressively destructive loss of bone and periodontal ligament (loss of the attachment apparatus of the teeth). Periodontitis has documented risk factors, including but not limited to specific plaque bacteria, smoking, and diabetes mellitus. Initially, the link between systemic disease and periodontal diseases was thought to be unidirectional. Currently, there is increasing evidence that the relationship between these entities may be bidirectional. Recent case-control and cross-sectional studies indicate that periodontitis may confer a 7-fold increase in risk for preterm low birth weight infants and a 2-fold increase in risk for cardiovascular disease. These early reports indicate the potential association between systemic and oral health. Additionally, these studies support the central hypothesis that periodontal disease involves both a local and a systemic host inflammatory response. This knowledge of disease interrelationships may prove vital in intervention strategies to reduce patient risks and prevent systemic disease outcomes. Based on the current evidence of the periodontal-systemic disease connection, the purpose of this report is to help establish the groundwork for closer communication between physicians and periodontists in the military health care setting.
Mil Med 2001 Jan
PMID:Periodontal disease and its association with systemic disease. 1119 6

Gingival diseases are the most widely dispersed diseases in the United States. In some patients, periodontal disease appears in a generalized form, but more often it appears in localized areas. Furthermore, after treatment with scaling and root planing in generalized cases, the disease is often reduced to a few local areas in the patient's mouth. Because periodontitis is a bacterial infection with known pathogenic microorganisms, the local delivery of antimicrobial agents has been considered to be a possible solution for treating and controlling localized forms of periodontal disease. Three local chemotherapeutic agents are reviewed in this paper: tetracycline fiber, doxycycline gel, and chlorhexidine chip. With the advancement of local drug delivery systems, restorative dentists, periodontists, and their patients have new alternatives for the treatment of periodontal disease. Local chemotherapeutic agents offer an additional mode of therapy and should be used on a case-by-case basis, not necessarily as an initial treatment.
Mil Med 2001 Nov
PMID:The use of chemotherapeutic agents in localized periodontal pockets. 1172 20