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Query: UMLS:C0031099 (periodontitis)
 12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The principle of GTR, guided tissue regeneration, was developed by Scandinavian scientists in order to separate epithelium and connective tissue from periodontal ligament cells and bone, thereby eliciting new attachment after marginal periodontitis. In case of jaw fractures loss of attachment may be seen in relation to teeth in the line of fracture, especially after severe dislocation of the fragments. One such patient is reported in whom only emergency treatment was possible during the first 11 days due to a simultaneous cerebral trauma. As anticipated a deep osseous pocket developed on the actual tooth 43 even if the fractures were anatomically repositioned and fixed with osteosynthesis and even if the postoperative course was uneventful. Later, treated by interpositioning of a resorbable Vicryl membrane, new attachment formed with a gain of the order of magnitude of 8 mm with concomitant osseous regeneration. It is concluded that Vicryl mesh would definitely seem to have a place in the treatment of jaw fractures. However, there is an urgent need for a larger collection of meshes than presently available, including both larger sizes and other shapes.
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PMID:[Resorbable Vicryl mesh for new attachment after jaw fracture]. 144 50

In 24 patients with advanced periodontitis 38 interproximal intrabony defects were treated by conventional surgery (C; n = 8) or guided tissue regeneration (GTR) using expanded polytetrafluoroethylene (G; n = 17) or Polyglactin 910 barriers (V; n = 13). Presurgically (BL), 6 and 12 months postsurgically clinical parameters (GI, PII, PPD, PAL-V) and 36 standardized radiographs were obtained generating 72 pairs (36 BL/6 months; 36 BL/12 months). Using linear measurements on the radiographs and subtraction analysis, bony fill within the defects was assessed. Intrasurgically the extension of the intrabony defects was measured. Statistically significant (p < 0.05) attachment gain was found after 6 (C: 2.4 +/- 1.6 mm; G: 3.2 +/- 1.6 mm; V: 3.4 +/- 1.5 mm) and 12 months in all groups (C: 2.4 +/- 1.7 mm; G: 3.1 +/- 1.7 mm; V: 4.0 +/- 1.7 mm). Thirty-nine of 72 pairs of radiographs were unsuitable for subtraction analysis. Significant (p < 0.05) bony fill was observed at 6 (C: 0.3 +/- 1.0 mm; G: 0.7 +/- 1.2 mm; V: 0.9 +/- 1.2 mm) and 12 months (C: 0.0 +/- 1.1 mm; G: 1.4 +/- 1.5 mm; V: 1.5 +/- 1.7 mm) only after GTR surgery. GTR therapy yielded significantly more bony fill than conventional surgery 12 months postsurgically (p < 0.1). Bony fill (linear measurement) was influenced by age, smoking, baseline bone loss and PAL-V gain (p < 0.0001). Significantly more radiographs taken with potentially unstable support of the filmholder were not suitable for subtraction analysis than those with stable support (p < 0.05). Bony gain (subtraction analysis) was positively modulated by bony fill (linear measurement) and use of biodegradable barriers (p = 0.002). There is a correlation between PAL-V gain and bony fill (linear measurement). Smoking impairs attachment gain and bony fill. Potentially stable support of the filmholder provided radiographs suitable for subtraction analysis.
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PMID:Evidence for healing of interproximal intrabony defects after conventional and regenerative therapy: digital radiography and clinical measurements. 965 77