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Query: UMLS:C0031099 (periodontitis)
 12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It was the objective of the present study to investigate the local inflammatory and immune response in patients with superficial (SMP) and progressive marginal periodontitis (PMP). In a preliminary study the distribution of macrophage subpopulations was analysed during experimental gingivitis using monoclonal antibodies. A significant increase in the number of inflammatory macrophages was observed during acute gingivitis. In the second part of the study, the distribution of the macrophage subpopulations, T-helper and -suppressor cells, B-lymphocytes and plasma cells as well as the total anaerobic microflora were determined during periodontal therapy. Before periodontal surgery PMP-patients demonstrated significantly more inflammatory macrophages and plasma cells and a significantly higher prevalence of Bacteroides gingivalis, Peptococcus species and Actinobacillus actinomycetemcomitans. The different local immune responses in PMP-patients might be caused by a distinct subgingival microflora, since no differences were observed in the number of the immunocompetent cells and the subgingival flora after successful periodontal treatment.
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PMID:[Comparative studies on progressive and superficial marginal periodontitis]. 214 92