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Query: UMLS:C0031099 (periodontitis)
 12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

According to the NHS, it is estimated that over 50% of the adult population are, to some extent, affected by gum disease and approximately 15% of UK population have been diagnosed with severe periodontitis. Periodontitis, a chronic polymicrobial disease of the gums, causes inflammation in its milder form, whereas in its severe form affects the surrounding tissues and can result in tooth loss. During periodontitis, plaque accumulates and sits between the junctional epithelium and the tooth itself, resulting in inflammation and the formation of a periodontal pocket. An interface is formed directly between the subgingival bacteria and the junctional epithelial cells. Bacterial pathogens commonly associated with periodontal disease are, among others, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, together known as the "red complex." This review will mostly concentrate on the role of P. gingivalis, a Gram-negative anaerobic bacterium and one of the major and most studied contributors of this disease. Because periodontal disease is associated with the development of atherosclerosis, it is important to understand the local immune response to P. gingivalis. Innate immune players, in particular, complement and antimicrobial peptides and their effects with regard to P. gingivalis during periodontitis and in the development of atherosclerosis will be presented.
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PMID:P. gingivalis in Periodontal Disease and Atherosclerosis - Scenes of Action for Antimicrobial Peptides and Complement. 2571 75

Objectives To establish current implant practice among university and hospital restorative dental specialists in the United Kingdom (UK) and Ireland and their opinions relating to criteria for implant treatment.Materials and methods An online questionnaire was distributed to 150 university and hospital restorative dental specialists in the UK and Ireland.Results The response rate was 27%. Twenty-nine (70%) respondents provided implant treatment, of which 76% and 100% placed and restored implants respectively. In addition, 79% worked with oral surgeons or oral and maxillofacial surgeons as part of the implant team. Hypodontia and malignancy were cited as the main groups that qualified for NHS dental implant treatment. Irradiation, smoking and bisphosphonates were considered the most important medical factors in patient selection for implant placement, while untreated periodontitis, poor oral hygiene and uncontrolled caries were the most important dental factors.Conclusions The majority of responding university and hospital restorative dental specialists within the UK and Ireland provide dental implant treatment and undertake a multidisciplinary approach where necessary. There is variation in the number of patients treated with implants by each respondent annually. The main patient groups that receive priority for NHS dental implant treatment are malignancy and hypodontia. Otherwise, there is general agreement about the factors considered important when selecting patients for implant treatment on the NHS and this aligns to the Royal College of Surgeons guidelines on selecting patients for the provision of dental implants.
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PMID:The provision of dental implants: current practice among university and hospital specialists in restorative dentistry within the UK and Ireland. 3206 Apr 51

Aims To assess the management of chronic periodontitis (CP) in general dental practices based in the West Midlands against the British Society of Periodontology (BSP) guidelines and determine whether this varies between NHS, private and mixed sector practices. To examine general dental practitioners' (GDPs') attitudes towards the management of periodontitis, the implementation of the BSP guidelines and explore their suggestions for improved management of the disease.Materials and methods A semi-structured telephone interview was conducted with eight dentists to construct an online questionnaire. Using the NHS Choices database, the practice managers of 30 dental practices were contacted and asked to distribute the online questionnaire to all GDPs within their practice.Results One hundred and three GDPs completed the questionnaire; several dentists indicated their management would not align with the BSP recommendations. Dentists do not believe the BSP guidelines are easy to implement in NHS practice.Discussion Areas where dentists are falling short of the BSP guidelines include periodontal charting, indications for root surface debridement (RSD) and antimicrobials. These topics should be highlighted to dentists. Dentists would prefer NHS remuneration to reflect the time and effort spent, better access to secondary care and increased awareness of periodontal diseases among patients.Conclusion This study identifies clear areas where dentists are not following the BSP guidelines and provides insight from a GDP's perspective to improve the management of CP in practice.
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PMID:An explorative study of the current practice and attitude towards the management of chronic periodontitis by general dental practitioners in the West Midlands. 3227 13