Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0031099 (periodontitis)
 12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Analysis of elements (mainly metals) in biological materials provides a challenge for analytics. It results from complex matrix of this kind of samples and strict requirements for purity at all stages of the analytical process. Over the years many effective methods for determination of metals in body fluids have been developed, which link with searching for the association between elemental composition of human body and various diseases. The aim of the investigation was to study the usefulness of available methodology to determination of selected metals in saliva and blood of patients with periodontitis and healthy controls by two techniques" ICP-MS and ICP-OES. Next statistical analysis of the data statistical was carried out. The influence of periodontal disease upon the concentrations of selected metals (Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Pb and Zn) in saliva was examined, as well the attempt to classify samples of patients with periodontitis and healthy individuals correctly was made. Additionally mutual relations between analytes in examined materials were determined by computing the Pearson's correlation coefficient and principal component analysis (PCA).
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PMID:[The influence of periodontal diseases on the concentration of selected metals in saliva]. 2342 Oct 36