Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0031099 (periodontitis)
12,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Histiocytosis X, a reticuloendothelial disorder, includes the three clinical syndromes: Letterer-Siwe and Hand-Schuller-Christian diseases and eosinophilic granuloma of the bone. Twenty-eight cases of adult onset of histiocytosis X involving the head and neck region were found in the literature during the past 20 years; 15 cases were confined to this area, out of which 13 involved jaw bones. Characteristic signs and symptoms of periodontal disease were observed in 22 out of 28 cases (79%) with the lower molar area as a predominant site. A case report of a non-osseous chronic disseminated histiocytosis X with periodontal involvement is presented. The importance of histiocytosis X, as an entity that should be kept in mind as a differential diagnosis of a process where destructive periodontitis is involved, is discussed.
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PMID:Periodontal manifestations of adult onset of histiocytosis X. 264 20