Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030794 (pelvic pain)
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Human Gene/Protein
LOC100130539 12.9
PDIK1L 11.9
RBM43 11.4
transcription factor DP-1 10.4
tropomodulin 3 10.1
CAB39L 9.8
RNF144B 9.8
G0S2 protein 9.6
carbamoylphosphate synthetase 9.6
LIN7C 9.5
KIFAP3 9.2
AOAH 9.1
ARHGAP12 8.9
integrin beta-3 8.9
RND1 8.8
Rho-guanine nucleotide exchange factor 8.8
semaphorin E 8.7
N-acetylglucosamine-6-O-sulfotransferase 8.7
Plexin-D1 8.7
acyloxyacyl hydrolase 8.6
semaphorin 3E 8.5
CRISPLD2 8.5
BAP-1 8.5
SEMG1 8.4
NFE2L3 8.4
GRB14 8.2
BACH 8.2
subtype EP3 8.1
carboxypeptidase A3 8.1
Slit-2 8.1
YTHDF3 8.1
chemokine (C-C motif) ligand 3 8.1
PRELP 8.0
p27K 7.9
CA-125 7.9
uroplakin II 7.9
SMOC2 7.8
PALS1 7.8
CYP1B1 protein 7.7
RAD51L1 7.6
tropomyosin 3 7.5
TLH 7.5
NPTX2 7.4
Endoribonuclease 7.3
Stomatin-like protein 2 7.2
uroplakin III 7.1
NCOA1 7.1
IQ motif containing GTPase activating protein 1 7.0
SLIT3 7.0
chorionic gonadotropin beta subunit 7.0
PID 6.9
TNFSF13B 6.9
KLF11 6.9
Serotonin receptor 6.8
T3E 6.8
E2F-2 6.8
prohibitin 2 6.8
WNT2B 6.7
syntaxin 5 6.7
NP3 6.7
RAPA 6.7
CAV2 6.6
claudin 2 6.6
PSN 6.6
T-STAR 6.6
PLAP 6.5
double-stranded RNA adenosine deaminase 6.5
UPA 6.5
DYS 6.4
semenogelin 6.4
prostaglandin E2 receptor 6.4
SYNE1 6.4
glial cell derived neurotrophic factor 6.4
persephin 6.3
Hic-5 6.3
Progesterone receptor 6.3
SIGIRR 6.3
WNT11 6.2
Hpr 6.2
MED12 6.2
more...
Disease
Chronic endocervicitis 12.9
Chlamydial prostatitis 12.9
fungal rash 12.9
Pelvic varices 12.2
pelvic congestion syndrome 12.1
Chronic prostatitis 12.1
Corpus luteum cyst 11.9
Upper urinary tract infection 11.9
Genital hemorrhage 11.9
Ovarian remnant syndrome 11.6
Allen-Masters syndrome 11.6
Chronic PID 11.5
Painful Bladder Syndrome 11.4
female genital disease 11.4
urinary bladder disorder 11.4
Endosalpingosis 11.4
Prostatitis 11.1
fimbrial cyst 10.9
TB salpingitis 10.9
Endolymphatic stromal myosis 10.9
Acute pelvic inflammatory disease 10.7
Adenomatous Polyp 10.6
Sexual pain disorder 10.6
Ovarian vein syndrome 10.6
Sclerosing stromal tumor 10.5
Endosalpingiosis 10.4
Nabothian cyst 10.4
Salpingitis isthmica nodosa 10.4
pelvic adhesions 10.3
Pelvic inflammatory disease 10.3
interstitial cystitis 10.3
Pelvic adhesions 10.2
Stromal sarcoma 10.2
Tubo-ovarian abscess 10.2
Hunner 10.2
Pelvic endometriosis 10.2
Osteitis pubis 10.1
retrograde menstruation 10.1
Primary dysmenorrhea 10.0
threatened labor 9.9
Anismus 9.9
leukorrhea 9.9
prostatitis 9.8
hematometra 9.8
Female Orgasmic Disorder 9.8
Ruptured ectopic pregnancy 9.8
pelvic instability 9.6
Retained products of conception 9.6
endometriosis 9.6
Ovarian pregnancy 9.5
Acute prostatitis 9.5
Pelvic infection 9.5
chronic salpingitis 9.4
Broad ligament 9.4
vaginismus 9.4
vaginismus 9.4
BPS 9.3
adenomyosis 9.3
Pelvic sepsis 9.1
Intrauterine adhesions 9.0
Colonic obstruction 8.9
proctalgia fugax 8.9
Mayer-Rokitansky-Kuster-Hauser syndrome 8.9
pelvic inflammatory disease 8.8
benign ovarian cyst 8.8
pyosalpinx 8.8
Endometrioma 8.6
Sampson 8.5
Adenoma malignum 8.5
Glassy cell carcinoma 8.4
Cornual pregnancy 8.4
Malignant struma ovarii 8.4
ectopic pregnancy 8.3
acute salpingitis 8.3
Meckel's diverticulitis 8.3
hypomenorrhea 8.3
chronic appendicitis 8.3
Round ligament 8.2
Primary infertility 8.2
lithopedion 8.2
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Symptom
PELVIC PAIN 12.9
Genitourinary pain 12.9
pelvic pain 12.9
Acute pelvic pain 12.7
Chronic pelvic pain 12.3
Anal discomfort 11.9
menstrual pelvic pain 11.9
Chronic pelvic pain syndrome 11.8
Prostatodynia 11.4
increased abdominal size 11.1
Lower abdominal pain 10.7
bladder pain 10.6
intermenstrual pain 10.6
Genital pain 10.4
dyschezia 10.2
prostatic tenderness 10.1
menometrorrhagia 10.1
penile discharge 10.0
calf cramps 9.6
Penile pain 9.6
vaginal pain 9.4
hematocolpos 9.0
Intermenstrual bleeding 8.9
UTI symptoms 8.9
postpartum pain 8.8
Vaginal dryness 8.8
vestibulitis 8.7
urinary frequency 8.7
Referred pain 8.2
difficulty with urination 8.2
Pain symptoms 8.1
left lower quadrant pain 8.0
dysuria 7.9
swollen scrotum 7.9
vaginal itching 7.9
right lower quadrant pain 7.5
Radicular pain 7.5
Vulvodynia 7.5
musculoskeletal disability 7.4
irregular bleeding 7.3
Central pain 7.3
iliac fossa pain 7.2
coccygodynia 7.2
tenesmus 7.2
Chronic abdominal pain 7.1
frequent urination 7.1
Visceral pain 7.1
GI irritation 7.0
nerve root irritation 6.9
Grimace 6.9
Urinary symptoms 6.7
neuralgia 6.6
Severe pain 6.6
bloating 6.6
lumbar back pain 6.5
feeling depressed 6.4
rectal pain 6.4
generalized abdominal pain 6.3
nerve pain 6.2
loin pain 6.2
Physical findings 6.1
acute abdomen 6.0
Joint hypermobility 6.0
groin pain 6.0
acute abdominal pain 5.9
abdominal fullness 5.8
urethral discharge 5.7
hot flushes 5.7
constipation 5.6
jaw pain 5.4
generalized pain 5.3
renal colic 5.3
pain 5.2
hot flashes 5.2
Cushingoid 5.2
limb pain 5.1
Cushingoid 5.1
low back pain 5.1
anal pain 5.0
abdominal pain 5.0
more...
Drug
Dienogest 9.9
Buserelin acetate 9.8
Ches 9.2
Aethoxysklerol 9.2
Nafarelin acetate 9.1
Nafarelin acetate 9.1
Elmiron 8.9
Naproxen sodium 8.5
Icodextrin 8.2
Lupron 7.6
Gestodene 7.1
mepivacaine hydrochloride 7.1
Tiaprofenic acid 7.0
Pregnyl 6.9
Arimidex 6.8
Triptorelin 6.7
Tolfenamic acid 6.5
Implanon 6.4
Ovulen 6.4
Zoladex 6.2
Levonorgestrel 6.1
Sulprostone 6.0
Surgicel 5.7
Clomiphene citrate 5.6
BOTOX 5.5
Norplant 5.2
Zoladex 4.9
ID2 4.8
Duloxetine 4.7
DEL 4.5
Fulvestrant 4.5
Lugol 4.3
Norplant 4.3
Omalizumab 4.3
Botox 4.2
Vinorelbine 4.2
Thyroglobulin 4.0
LMWH 3.9
Misoprostol 3.8
EE2 3.8
Emodin 3.8
Triad 3.7
Taxotere 3.7
Depo-Provera 3.6
HCG 3.6
Domperidone 3.5
Trib 3.5
Bayer 3.3
Ofloxacin 3.3
DEX 3.1
MAP 3.0
Luteinizing 2.9
Etoposide 2.8
Azithromycin 2.7
Fentanyl 2.6
Gleevec 2.4
CAM 2.4
Indomethacin 2.3
VCR 2.3
Docetaxel 2.2
ROC 2.0
ACT 1.9
Estrogens 1.8
CDP 1.7
Imatinib 1.7
Forskolin 1.6
Histamine 1.5
ALA 1.5
ENT 1.5
Rituximab 1.5
Taxol 1.3
Vitamin E 1.3
CTX 1.2
ampicillin 0.9
ROS 0.7
Gel 0.7
ICI 0.5
CTX 0.5
CTX 0.5
vitamin E 0.4
more...
Enzyme
acyloxyacyl hydrolase 8.5
hydroxyprostaglandin dehydrogenase 6.3
estrogen sulfotransferase 6.0
botulinum neurotoxin 5.5
17beta-HSD 5.3
estrogen sulfotransferase 4.8
17beta-HSD 4.5
ADPase 3.8
MAT 3.4
MCS 3.3
MAT 3.2
prostaglandin synthetase 3.1
GAS 3.0
5alpha-reductase 2.9
5alpha-reductase 2.9
21-hydroxylase 2.7
arylsulfatase 2.7
tryptase 2.5
purine nucleoside phosphorylase 2.5
apyrase 2.4
CPT 2.3
CD10 2.3
CPT 2.2
prostate-specific antigen 2.2
prostate-specific membrane antigen 2.2
TdT 2.1
MMP 1.9
phosphoglycerate kinase 1.8
PDK1 1.8
CPT 1.8
MAP 1.7
DNA methyltransferase 1.7
focal adhesion kinase 1.6
MDP 1.5
tissue plasminogen activator 1.5
sulfatase 1.3
granzyme B 1.3
enolase 1.1
arginase 1.1
citrate synthase 0.8
hyaluronidase 0.8
phosphodiesterase 0.7
MIP 0.7
luciferase 0.5
phosphoinositide 3-kinase 0.4
MEK 0.4
hyaluronidase 0.3
caspase-1 0.3
choline acetyltransferase 0.3
CYP3A4 0.3
mitogen-activated protein kinase 0.2
APC -0.1
cdc2 -0.1
xanthine oxidase -0.1
guanylate cyclase -0.1
lipoxygenase -0.1
plasmin -0.2
elastase -0.2
ERK -0.3
topoisomerase -0.3
NADPH oxidase -0.4
urokinase-type plasminogen activator -0.4
peroxidase -0.5
NADPH oxidase -0.5
acid phosphatase -0.7
thromboplastin -0.8
PARP -0.8
thrombin -1.1
caspase-3 -1.2
collagenase -1.2
lipase -1.2
adenylate cyclase -1.3
superoxide dismutase -1.3
trypsin -1.4
alkaline phosphatase -1.6
protein kinase -1.8
catalase -1.8
acetylcholinesterase -1.9
ATPase -2.1
protein kinase C -2.6
more...
Compound
MER 25 10.1
KI3 8.1
Norethisterone acetate 7.7
Nafarelin 7.5
Danazol 7.4
Terazosin 7.4
Oxamniquine 7.3
Pregnane 7.3
VCC 7.1
Palmitoylethanolamide 7.1
Lynestrenol 7.1
PID 7.0
Tamsulosin 7.0
PID 7.0
Clomid 6.7
Levonorgestrel 6.7
Zafirlukast 6.7
Medroxyprogesterone 6.6
Botulinum toxin type A 6.5
Cilag 6.5
Aminoglutethimide 6.2
CPP 6.1
Lipoxin A4 6.1
CPP 6.0
RU-486 6.0
Delphinidin 5.8
Clomiphene citrate 5.7
BEP 5.7
CHM 5.6
Mefenamic acid 5.4
Clomiphene 5.4
Roxithromycin 5.3
T13 5.3
Norethisterone 5.2
Tranexamic acid 5.1
HIS 4.8
Doxazosin 4.8
Phenylbutazone 4.6
A 42 4.4
Lycopene 4.4
Apigenin 4.4
Hematoxylin 4.2
Lawson 4.2
Mato 4.0
DPN 4.0
Estrogen 4.0
Ketoprofen 4.0
Ifosfamide 3.9
PGFM 3.8
Bupropion 3.8
Organon 3.8
MAK 3.6
Naproxen 3.6
Progesterone 3.6
Amitriptyline 3.6
TCDD 3.6
MPA 3.5
MPA 3.5
Luteolin 3.5
Tramadol 3.5
HPT 3.5
Ofloxacin 3.5
HPP 3.5
MPA 3.4
Estrogen 3.4
RELA 3.4
SSD 3.3
BSO 3.3
tetradecyl 3.3
tetradecyl 3.3
T10 3.3
17-OHP 3.3
LCR 3.3
Pentoxifylline 3.3
MAD 3.2
Ibuprofen 3.2
DEX 3.1
Estradiol 3.1
TCC 3.1
Vincristine 3.1
more...