Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0030794 (
pelvic pain
)
4,056
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 53-year-old female patient presented with lumbar and
pelvic pain
. The
18
F-fluorodeoxyglucose (
18
F-FDG) positron emission tomography/computed tomography scintigraphy showed extensive bone destruction with hypermetabolic osteolysis, with increased
18
F-FDG uptake. The histological examination of the pubic bone lesion revealed a metastatic tumor. Neither chemotherapy nor radiotherapy could control the condition. More than a year later, the patient underwent a total thyroidectomy with cervical lymph node clearance. The histological examination revealed a papillary thyroid microcarcinoma (PTMC) in the left lobe with capsular invasion.
131
I treatment with
thyroid hormone
withdrawal followed. The
131
I whole-body scintigraphy showed extensive uptake in the basic thyroid deposits, most bones and both lungs. Three months after the
131
I treatment, the patient succumbed to cachexia. The present case indicated that not all PTMCs have excellent prognosis and that, despite being rare, clinically significant metastases can arise from a PTMC.
...
PMID:Extensive bone metastases as the initial symptom of papillary thyroid microcarcinoma: A case report. 2613 42
