Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030794 (pelvic pain)
 4,056 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The gonadotropin-releasing hormone (GnRH) agonists are a relatively new class of drugs that are potentially effective in treating disorders that are aggravated either by estrogen or testosterone. GnRH agonists are effective in the treatment of endometriosis, as well as other disorders, such as advanced prostrate cancer, precocious puberty and uterine leiomyomata. While the GnRH agonists reduce the extent of the endometrial lesions and the occurrence of pelvic pain associated with endometriosis, these agents are associated with physical and psychiatric side effects. The adverse effects of these agents are consistent with the physiological effects of ovarian suppression, such as vasomotor instability, vaginal dryness, and headaches. Preliminary results of a prospective, double-blind placebo-controlled study and an open label trial indicates that depressive mood symptoms increase in women treated with GnRH agonist therapy for endometriosis. Additional evidence suggest that sertraline effectively manages depressive mood symptoms associated with GnRH agonist therapy. The reason for the decline in mood on GnRH agonists is postulated to be associated with the decline in estrogen levels. Effective treatment strategies for depressive mood symptoms in women on GnRH agonists therapy may offer insight into the mechanisms of action of estrogen on mood.
 ...
PMID:Depressive symptoms associated with gonadotropin-releasing hormone agonists. 970 54

Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures we examined small pelvis and 17 patients were additionally undergone chromotubation. These procedures lasted 8-24 minutes. No complications were noticed during and after operations. Microlaparoscopy were verified by laparoscopy with positive correlation of data. Advantages and limitations of microlaparoscopy were taken into consideration. We presented possibilities of the new diagnostic technique in gynaecology.
 ...
PMID:[Diagnostic micro-laparoscopy in gynecology]. 1053 30

Chronic pelvic pain afflicts 5-10% of women. The diagnosis of its cause is predominantly assessed by means of laparoscopy which in 60-70% reveals various organic causes of pain. The retrospective study analyses the results of 43 laparoscopic examinations indicated due to chronic pelvic pain. The average age of patients was 29.97 years. Organic findings on internal genitals were found in 36 cases (83.7%). Endometriosis was diagnosed in 11 cases (25.6%). According to the criteria of American Fertility Society, 4 patients (36.4%) suffered from stage I, 6 patients (54.5%) suffered from stage II, and only one case (9.1%) was caused by stage III. Chronic inflammatory process was diagnosed in 12 cases (18.6%), adhesions without any other pathologic findings in 8 cases (18.6%), and ovarial cysts in 3 cases (7.0%). Varicose pelvic veins and uterine myoma occurred in one case (2.3%), respectively. In 7 cases, no pathological change was revealed. Laparoscopy in coincidence with chronic pelvic pain is a significant examination which helps to reveal the organic origin of disturbance. An early decision of applying this invasive examination contributes to fast assessment of the diagnose and commencement of treatment. (Tab. 2, Fig. 1, Ref. 32.)
 ...
PMID:[Laparoscopic findings in women with chronic pelvic pain]. 1115 72

Uterine artery embolization for symptomatic leiomyomas is a new attractive treatment in patients who do not desire pregnancy and for whom conventional therapy has failed. Uterine fibroid embolization can also be considered for patients who desire pregnancy when myomectomy is technically difficult or/and in case of recurrence after myomectomy. 90% improvements are commonly reported in abnormal bleeding, pelvic pain, and in bulk-related symptoms. This technique allows reduction of the hospital stay, the convalescence period, the morbidity and the mortality rate compared to conventional surgical treatment.
 ...
PMID:[Uterine fibroids embolization: a review]. 1193 21

Conscious sedation and analgesia are integral components of successful uterine fibroid embolization (UFE), both in providing comfort to the anxious patient undergoing an elective procedure and for providing relief of the severe pelvic pain, cramps, and nausea that may result from acute uterine ischemia and the postembolization syndrome that may follow. The agents used are typically those with which interventional radiologists already have extensive experience in the performance of a variety of invasive procedures. Immediate postprocedure care benefits greatly from the use of narcotic delivered via PCA (patient-controlled analgesia) pump. Nonsteroidal anti-inflammatory drugs (NSAIDs) are also particularly useful for treating the pain and cramping caused by UFE and help reduce the amount of narcotic necessary for pain relief during the recovery period. Detailed instructions for the first week of convalescence are necessary to insure comfort and avoid complications.
 ...
PMID:III. Uterine fibroid embolization: pain management. 1209 6

Uterine artery embolization is a new method of treating uterine leiomyomata, first carried out in France in the early 90s. The procedures involve placing a small catheter into an artery in the groin and directing it to the blood supply of the fibroid. Little plugs of polyvinyl alcohol are injected through the catheter to block these arteries. This cause the fibroid to shrink. Indications for uterine fibroid embolization include menorrhagia, pelvic pain or pressure, other "bulk" syndrome (low-back pain, urinary frequency and constipation. The fluoroscopic-guided procedure is performed under local anesthesia. Most patients are discharged within 72 hours. Post-embolization syndrome including severe pain is managed with morphine via patient-controlled pump. Paper reviews long term outcomes. Uterine artery embolization has several advantages: high efficacy, less invasiveness, ability to treat multifocal changes, uterine preservation, shorter hospitalisation and recovery (low cost) and disadvantages: postembolic syndrome (pain and fever), unknown relations to pregnancy and lack of long term results.
 ...
PMID:[Uterine arteries embolization as a treatment of uterine leiomyoma]. 1271 43

Of the first 500 women in Oxford to undergo transcervical resection of the endometrium, 101 (20%) have subsequently undergone hysterectomy. This study was undertaken to assess the reasons for failure of endometrial resection. An audit of the case notes of the 101 women requiring hysterectomy was performed. Data collection included the patient's age, weight, parity, reasons for endometrial resection, details of the endometrial resection, reasons for hysterectomy, hysterectomy findings and uterine histology. Six (6%) hysterectomies were performed as emergency operations during endometrial resection, 33 (33%) were performed for persistent menorrhagia, 39 (39%) for recurrent menorrhagia and in 18 women (18%) for pelvic pain. The duration of success following endometrial resection ranged from 0 to 21 months. Hysterectomy was significantly more common in older women under 40 years of age, in the presence of an enlarged fibroid uterus, when complications at endometrial resection had occurred and in women operated on by relatively inexperienced surgeons. Endometrium ws present in 96% of hysterectomy specimens. Uterine malignancy that had not been diagnosed at transcervical resection of the endometrium was present at hysterectomy in two women. Hysterectomy should be considered in preference to endometrial resection for treatment of menorrhagia in women who are less than 40 years old and in the presence of large intramural fibroids.
 ...
PMID:Hysterectomy following failed endometrial resection. 1551 76

We report two cases of intravenous leiomyomatosis, a rarely described benign tumor, which illustrate potential complications resulting from metastatic dissemination. Both cases were fortuitously discoveries. We discuss the diagnostic problems, etiological factors, therapeutic management and prognosis. Hysterectomy with bilateral salpingo-oophorectomy and regular follow-up with cardiac and pulmonary monitoring were performed. Pelvic pain disappeared and the patients are recurrence-free. The main difficulties concerned early diagnosis, complete resection and prognosis. These cases illustrate the importance of careful pathology examination of all uterine myoma resection specimens.
 ...
PMID:[Intravascular leiomyomatosis of the uterus. Two cases and review of the literature]. 1568 48

The female genital system is rarely affected in von Recklinghausen neurofibromatosis. The vulva is the most frequent genital location, but vaginal, cervical, uterine, and ovarian neurofibromas have rarely been reported. We describe a case of plexiform neurofibroma affecting the uterine cervix in a patient with chronic pelvic pain and menorrhagia who had multiple cutaneous neurofibromas and 1 large paraspinal neurofibroma. A small plexiform neurofibroma, which was not grossly visible, was confined to the uterine cervix and coexisted with a uterine leiomyoma and adenomyosis. There were no neurofibromas in the myometrium, fallopian tubes, or ovaries. Plexiform neurofibroma is a neoplasm that should be considered in the differential diagnosis of spindle cell neoplasms of the uterine cervix, especially in specimens from patients with neurofibromatosis.
 ...
PMID:Plexiform neurofibroma of the uterine cervix: a case report and review of the literature. 1591 29

Non-puerperal uterine inversion is extremely rare. We report a case associated with leiomyoma. It is presented the case of a multiparous of 46 year-old for presenting severe vaginal bleeding, pelvic pain and strange body vaginal sensation. The diagnosis was uterine myoma in abortive phase. An abdominal hysterectomy was performed to find a complete uterine inversion. This report represents an anecdotal case of non-puerperal uterine inversion successfully treated surgically.
 ...
PMID:[Non-puerperal uterine inversion. Report of a case]. 1630 39


<< Previous 1 2 3 4 5 6 7 8 9 Next >>