Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030794 (pelvic pain)
4,056 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In order to evaluate the efficiency of Danazol treatment on pelvic endometriosis, a laparoscopic control with photographs was performed before treatment in 33 cases. Of these 20 were severe (group A), seven mild (group B) and six light (group C), according to the American Fertility Society classification, and 15 patients were infertile, 10 had pelvic pain and eight had dysmenorrhoea. Among the 28 patients who accepted a laparoscopic control after 6 months of treatment, the result was quite good in 50% of the cases in groups B and C, an improvement was seen in 30% of the patients in groups A and B, but a failure in 50% of the cases, especially in group A. Of the 14 cases with an ovarian cyst greater than 3 cm in diameter an operation was necessary either by laparoscopy (four cases) or by laparotomy (five cases). Seven pregnancies were established out of 15 cases of infertility, but a relapse was noticed in 30% of the cases. In conclusion, it appears that Danazol therapy is effective in mild or light endometriosis, but is not sufficient in cases of ovarian endometriosis with cysts greater than 3 cm in diameter.
...
PMID:Laparoscopic control of danazol therapy on pelvic endometriosis. 296 11

The sonographic appearance of hemorrhagic ovarian cysts (HOC) has received little attention aside from a recent report in adolescent girls. We reviewed the sonographic findings in 14 adults with 15 pathologically proven HOC to see whether there were any consistent sonographic findings that, along with the clinical history, might make possible the diagnosis. The majority (93%) of patients presented with the abrupt onset of lower abdominal or pelvic pain, and each, when clinically appropriate, had a negative serum pregnancy test. Sonographically, all of the masses were cystic except one. The cyst wall was thin and well defined in six cases and thick and irregular in eight. The majority (87%) had internal echoes. These echoes were scattered and low level or diffuse and homogeneous (27%) or complex and echogenic (53%) in nature. Two cysts had numerous septations, and another had a fluid--debris interface. If the pain subsides and the hematocrit remains stable, the premenopausal patient can be managed conservatively. Sonographic follow-up is recommended so that an underlying hemorrhagic ovarian cystic neoplasm can be excluded. This was present in three of our patients, two of whom were postmenopausal.
...
PMID:Sonography of hemorrhagic ovarian cysts. 309 45

2 case histories of severe pelvic infection and tuboovarian abcesses associated with use of the Majzlin Spring intrauterine device are presented. A 30-year-old parous white woman and a 25-year-old parous black woman were admitted to the Brooklyn-Cumberland Hospitals on separate occassions with a history of prolonged fever, diarrhea, pelvic pain and vomiting. After failure of antibiotic therapy, exploratory laparotomies revealed severely infected ovarian cysts and tuboovarian abscesses with the Majzlin Spring device deeply implanted in the endometrium. Total abdominal hysterectomies and bilateral salpingo-oophorectomies were performed. Although preexisting disease conditions could have existed in these women before the IUD insertion, a cause-and-effect relationship between the IUD as a carrier of a superimposed infection and these conditions should be considered. Much greater care should be taken in the insertion, re-insertion, and follow-up of these devices.
...
PMID:Tuboovarian abscess and the intrauterine device (Majzlin Spring). 469 75

The authors report on a retrospective study of 184 laparoscopies carried out assessing the aetiology of chronic pelvic pain. The population that was studied has a mean age of 28.8 years, with most of the patients being between 20 and 30 years of age. The mean length of the history of the pain was 51 1/2 months. 51% of the cases had pain of a rhythmical nature associated with the menstrual cycle, 11.3% of cases had deep dyspareunia and 37.7% of the cases had repeated attacks of pain. Previous gynaecological pathology was found in 30% of cases and previous pelvis surgery in 11.1% of cases. 41.5% of the population were multiparous. Laparoscopy was only performed after a full clinical and paraclinical examination. It showed the presence of: endometriosis in 22.2% of cases, pelvic adhesions in 17.4%, varicose veins in the pelvis in 11.4%, ovarian cysts in 6.5%, ovarian dystrophies in 3.2%, Masters and Allen syndrome in 3.8%, sub-serous fibroids in 2.1%.
...
PMID:[The diagnostic value of celioscopy in the evaluation of chronic pelvic pain. Apropos of 184 cases]. 623 46

One hundred twelve females below the age of twenty years underwent laparoscopy at the Medical University of South Carolina over a ten-year period. Pelvic pain followed by primary amenorrhea was the major indication for the procedure. Eighty-nine percent of those with acute pain had identifiable pelvic pathology, whereas 27% of girls presenting with chronic pain had a normal laparoscopic examination. Pelvic inflammatory disease was the most common diagnosis. Ovarian cysts, pregnancy complications, and endometriosis were also found. Endometriosis was not found among black teenage clinic patients. The procedure appears to be a safe and useful diagnostic tool in this age group.
...
PMID:Laparoscopy in children and adolescents. 623 18

Chlamydia are a frequent etiologic agent in the chronic salpingitis that has become more and more of a problem in recent years, with its accompanying pelvic pain, ectopic pregnancies, and tubal sterility. Although public health officials, obstetricians and gynecologists, and sexually transmitted disease specialists all agree that prevention would be preferrable to treatment of the resulting tubal lesions and possible neonatal complications, the change of habits necessary for prevention will be difficult to achieve. Infection can be avoided by discouraging early initiation of sexual activity in adolescents, who are apparently particularly susceptible to chlamydial infection, and by discouraging multiple sexual partners since the risk increases appreciably for those having over 3 partners. Condoms and local spermicides with a benzalkonium chloride base offer protection but are poorly accepted by adolescents. IUDs should not be used by adolescents because of the risk of infection. Diagnosis of chlamydia is difficult because about 60% of cases in women are asymptomatic. Persons at high risk because of their patterns of sexual activity should be examined regularly for chlamydia, and tests should be scrupulously performed at all stages and sent to a competent laboratory. All sexual contacts of the chlamydia patient and all their sexual contacts should be treated. An early diagnosis of tubal involvement is difficult but should be pursued through laparoscopy and taking the necessary samples. The public should be educated about the existence, gravity, consequences, and contagiousness of sexually transmitted diseases in such institutions as schools and the military service. Treatment of chlamydia includes early and intensive antibiotic therapy, complete rest, and prolonged use of corticotherapy. An oral contraceptive can be prescribed to prevent development of functional ovarian cysts. Laparoscopic control is essential to ensure that the cure was effective. Return of the infection is associated with a very poor prognosis.
...
PMID:[Prevention of Chlamydia trachomatis infections in women]. 652 58

At this time the ideal contraceptive, i.e., the safe, simple, inexpensive, totally effective, easily reversible contraceptive without side effects and not used at the time of the sexual act, has yet to be developed. This review highlights recent improvements in standard contraceptives and the views of these physicians concerning current risk benefit ratios. The benefits of tubal ligation are obvious, for few procedures offer more relief from anxiety and have such a high chance of success. Failure rates with tubal ligation range from 1 in 200 to 1 in 1000 cases, depending on the type of operation performed. Advances in laparoscopic technique, including the use of either silastic bands or spring loaded clips, have virtually eliminated the inadvertent "burns" associated with electrocautery. Due to the fact that clips and bands produce less tissue damage, it is anticipated that there will be a higher potential for reversibility. Recent literature has emphasized a specific syndrome that develops subsequent to tubal ligation; its major components are dysfunctional uterine bleeding and pelvic pain. The true incidence of this syndrome is difficult to establish but is estimated to be 10-33% in women who have had laparoscopic tubal fulguration. Vasectomy is simpler with less immediate morbidity, less expense, and easier reversibility than tubal ligation. The failure rate is slightly less with male sterilization. The most alarming recent report in relation to vasectomy is that it may be a surgical model for autoimmune disease. The theoretical effectiveness of steriodal contraceptives is 1 pregnancy/1000 woman years of use, and the actual use effectiveness is 5-8 pregnancies/1000 woman years of use. Many review articles document the various adverse effects that have been recorded in the literature. The mortality risk from oral contraceptive (OC) use in women under age 35 is 3 in 100,000. Few authors comment on the beneficial effects of OCs. These include fewer menstrual disorders, inhibition of the development of benign breast disease and a decrease in the incidence of functional ovarian cysts, and a decrease in some medical illnesses including peptic ulcers and rheumatoid arthritis. Liver adenomas are the most prominent complication of OCs that have been related to chronic use. The IUD has several benefits including a failure or pregnancy rate of 2-3/100 woman years of use. OCs are 3 times more dangerous than the IUD in regard to mortality, but the incidence of hospitalizations is 5-10 times higher with the IUD than with OCs. As effectiveness of barrier methods depends on high motivation, in studies of all forms of vaginal contraception and condoms there is a wide discrepancy between theoretical and use effectiveness. The lowest mortality rates are associated with barrier contraceptives with a back-up of early abortion when the method fails.
...
PMID:Effectiveness and risks of contraception. 699 15

Unusually effective and long-lasting relief of pelvic pain of gynaecological origin has been obtained consistently by short exposures of affected areas to the application of a magnetic induction device producing short, sharp, magnetic-field pulses of a minimal amplitude to initiate the electrochemical phenomenon of electroporation within a 25 cm2 focal area. Treatments are short, fasting-acting, economical and in many instances have obviated surgery. This report describes typical cases such as dysmenorrhoea, endometriosis, ruptured ovarian cyst, acute lower urinary tract infection, post-operative haematoma, and persistent dyspareunia in which pulsed magnetic field treatment has not, in most cases, been supplemented by analgesic medication. Of 17 female patients presenting with a total of 20 episodes of pelvic pain, of which 11 episodes were acute, seven chronic and two acute as well as chronic, 16 patients representing 18 episodes (90%) experienced marked, even dramatic relief, while two patients representing two episodes reported less than complete pain relief.
...
PMID:Electrochemical therapy of pelvic pain: effects of pulsed electromagnetic fields (PEMF) on tissue trauma. 753 Oct 30

In this study we present 41 cases of endoscopy surgery in gynecology done in Saint Charles Hospital for: extra-uterine pregnancies (GEU), pelvic abscess, pelvic endometriosis, ovarian cysts (KO), polycystic ovaries (PKO), primary amenorrhea, postoperative pelvic adhesions, uterine fibroma and appendicitis. These patients consulted for infertility, irregular menses and pelvic pain. The procedures done were the following: salpingectomy, endo-tubal aspiration, pelvic abscess drainage and IUD removal, endometrial implants coagulations, excision of ovarian cysts, multiple ovarian punctures (MPO), wedge resection of ovaries, ovarian biopsies, adhesiolysis, myomectomies, hysterectomies and appendectomies. The final results and smooth post-operative course are in favour of the technical and therapeutic advantages of the endoscopic surgery in gynecology as a conservative, functional and preventive procedure.
...
PMID:[Gynecologic endoscopic surgery at Saint-Charles Hospital. Review of the literature]. 762 32

This study assessed whether hysteroscopy can provide information concerning the cause of chronic pelvic pain. We prospectively evaluated the findings in 547 consecutive patients who had laparoscopy to evaluate chronic pelvic pain at a large, referral-based clinic and outpatient suite of a suburban hospital. Forty-eight had previous hysterectomies. The remaining 499 had hysteroscopy during the same surgery and met the following qualifications: chronic pelvic pain, dysmenorrhea, dyspareunia, dysuria, back pain, pelvic pressure or dyschezia for a duration greater than six months and previous failed medical therapy. When endometriosis was the primary diagnosis at laparoscopy, hysteroscopy revealed abnormalities in 62 (32.5%) of 191 patients. At hysteroscopy, 46 of 105 patients (43.8%) with single or multiple leiomyomas of significant sizes diagnosed laparoscopically were noted to have pathology within the uterine cavity. Ten of 11 patients (90.9%) found to have ovarian cysts underwent hysteroscopy. Four (40%) had uterine abnormalities; the most common was cervical stenosis. Pelvic adhesions were found in 118 patients (21.6%). Eighty-nine underwent hysteroscopy, and 24 (27%) had intrauterine abnormalities. Ninety-six patients (17.5%) who underwent laparoscopic evaluation had endometriosis and pelvic adhesions. Ninety-three of these underwent hysteroscopy, and abnormalities were noted in 26 (28.0%). In eight women (1.5%) no abnormality was found at laparoscopy. Two underwent hysteroscopy, and no abnormality was noted in either woman. Hysteroscopy provides useful, adjunctive information and may improve the diagnosis and treatment of chronic pelvic pain.
...
PMID:Use of hysteroscopy in addition to laparoscopy for evaluating chronic pelvic pain. 765 Jun 54


<< Previous 1 2 3 4 5 6 7 8 9 Next >>