Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0030567 (Parkinson's disease)
63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein synuclein 0.043 alpha-synuclein 0.034 LRRK2 0.011 parkin 0.010 leucine-rich repeat kinase 2 0.009 tyrosine hydroxylase 0.009 SNCA 0.008 DJ-1 0.007 Parkin 0.007 PINK1 0.007 MPP 0.007 dopamine transporter 0.004 STN 0.003 PARK2 0.003 DBS 0.003 PARK7 0.002 Leucine-rich repeat kinase 2 0.002 MAO-B 0.002 glucocerebrosidase 0.002 PARKIN 0.002 glial cell line-derived neurotrophic factor 0.002 ATP13A2 0.001 PARK6 0.001 PARK8 0.001 synphilin-1 0.001 CIT 0.001 alpha synuclein 0.001 Nurr1 0.001 GBA1 0.001 beta-synuclein 0.001 vesicular monoamine transporter 2 0.001 catechol-O-methyltransferase 0.001 dopa decarboxylase 0.001 Kufor-Rakeb syndrome 0.001 ubiquitin 0.001 neurotrophic factor 0.001 VPS35 0.001 prion 0.001 Synphilin-1 0.000 amyloid precursor protein 0.000 proteasome 0.000 with Parkinsonism 0.000 gamma-synuclein 0.000 NACP 0.000 UCH-L1 0.000 CHCHD2 0.000 tau protein 0.000 TH protein 0.000 Alpha synuclein 0.000 SYN 0.000 olfactory 0.000 VMAT2 0.000 PITX3 0.000 DAT 0.000 neuronal protein 0.000 FBXO7 0.000 Dopamine transporter 0.000 MAO-A 0.000 neurturin 0.000 GDNF 0.000 DNAJC13 0.000 COMT 0.000 dopamine D2 receptor 0.000 Mol 0.000 brain-derived neurotrophic factor 0.000 MSA 0.000 Monoamine oxidase B 0.000 OMD 0.000 caspase-3 0.000 vacuolar protein sorting 35 0.000 F-box only protein 7 0.000 PLA2G6 0.000 RAB7L1 0.000 PTEN 0.000 MDS 0.000 NURR1 0.000 LRRK1 0.000 EIF4G1 0.000 axonal 0.000 GPR37 0.000 more...

Disease Parkinson's disease 1.000 parkinsonism 0.029 Alzheimer's disease 0.012 dyskinesia 0.011 movement disorder 0.008 Dementia with Lewy bodies 0.007 Huntington's disease 0.006 dementia 0.006 progressive supranuclear palsy 0.005 akinesia 0.005 amyotrophic lateral sclerosis 0.004 abnormal involuntary movements 0.003 PARK2 0.003 REM sleep behavior disorder 0.002 PARK7 0.002 cognitive impairment 0.002 impulse control disorder 0.001 PARK8 0.001 hallucinations 0.001 PARK6 0.001 depression 0.001 multiple sclerosis 0.001 behavior disorder 0.001 camptocormia 0.001 Multiple system atrophy 0.001 PARK1 0.001 hemiparkinsonism 0.001 schizophrenia 0.001 neurological disease 0.001 restless legs syndrome 0.001 sleep disorders 0.000 hypersexuality 0.000 catalepsy 0.000 neuroblastoma 0.000 Essential tremor 0.000 psychosis 0.000 Pisa syndrome 0.000 stroke 0.000 Gaucher disease 0.000 pathological gambling 0.000 KRS 0.000 sleep disturbances 0.000 PARK4 0.000 epilepsy 0.000 dysautonomia 0.000 MSA 0.000 CNS diseases 0.000 Tourette syndrome 0.000 PARK3 0.000 PARK11 0.000 Pick's disease 0.000 PARK10 0.000 PDD 0.000 PARK13 0.000 MDS 0.000 induced psychosis 0.000 PARK5 0.000 parasomnia 0.000 Neurodegenerative Disorders 0.000 Sleep attacks 0.000 tardive dyskinesia 0.000 Dystonia 0.000 delusions 0.000 motor neuron disease 0.000 Globus 0.000 Hypokinetic dysarthria 0.000 olivopontocerebellar atrophy 0.000 dysphagia 0.000 Parkinson's disease and parkinsonism 0.000 senile dementia 0.000 PSP 0.000 Friedreich's ataxia 0.000 drug addiction 0.000 apraxia 0.000 PARK12 0.000 GSH 0.000 obsessive-compulsive disorder 0.000 Creutzfeldt-Jakob disease 0.000 Juvenile Parkinsonism 0.000 Hallervorden-Spatz disease 0.000 more...

Symptom bradykinesia 0.019 tremor 0.011 motor symptom 0.004 dystonia 0.002 apathy 0.001 Rest tremor 0.000 muscle rigidity 0.000 visual hallucination 0.000 abnormal gait 0.000 sleepiness 0.000 Parkinsonian tremor 0.000 constipation 0.000 dysarthria 0.000 chorea 0.000 Involuntary Movement 0.000 drooling 0.000 Postural tremor 0.000 ataxia 0.000 insomnia 0.000 Parkinsonian rest tremor 0.000 functional recovery 0.000 myoclonus 0.000 pain 0.000 fatigue 0.000 Antecollis 0.000 cerebellar ataxia 0.000 intention tremor 0.000 blepharospasm 0.000 anosmia 0.000 dribbling saliva 0.000 eds 0.000 Motor dysfunction 0.000 Frozen gait 0.000 nausea 0.000 Hypometria 0.000 Poverty of facial expression 0.000 Other hallucinations 0.000 Cog-wheel rigidity 0.000 Pleurothotonus 0.000 Persistent tremor 0.000 memory loss 0.000 catatonia 0.000 athetosis 0.000 spasticity 0.000 Primary orthostatic tremor 0.000 Retropulsion 0.000 dizziness 0.000 Swallowing problems 0.000 Ballismus 0.000 posthemiplegic chorea 0.000 Extrapyramidal symptoms 0.000 amimia 0.000 seizures 0.000 agitation 0.000 hypersomnia 0.000 Decreased activity 0.000 hypertonia 0.000 Senile tremor 0.000 Gustatory rhinorrhea 0.000 Leg discomfort 0.000 lightheadedness 0.000 Depressive symptoms 0.000 Limb dystonia 0.000 Urinary symptoms 0.000 weakness 0.000 impaired motor coordination 0.000 Psychiatric symptoms 0.000 muscle stiffness 0.000 Behavioral symptoms 0.000 thinning 0.000 impaired body balance 0.000 loss of balance 0.000 Stepping 0.000 Fear of falling 0.000 Fear of falling 0.000 tactile hallucination 0.000 forgetfulness 0.000 syncope 0.000 dysosmia 0.000 torticollis 0.000 more...

Drug Parkin 0.007 Parkin 0.007 DBS 0.003 Sinemet 0.001 Sinemet 0.001 Rasagiline 0.001 Pramipexole 0.001 Pramipexole 0.001 Sinemet 0.001 Rotigotine 0.001 Madopar 0.001 Apomorphine 0.001 Eldepryl 0.000 Istradefylline 0.000 Eldepryl 0.000 Carbidopa 0.000 3,4-Dihydroxyphenylalanine 0.000 Azilect 0.000 MDS 0.000 Droxidopa 0.000 Mirapex 0.000 Lisuride 0.000 Comtan 0.000 Frontal 0.000 ROS 0.000 CFT 0.000 Permax 0.000 Permax 0.000 Zydis 0.000 Lazabemide 0.000 Zonisamide 0.000 Posture 0.000 Benserazide 0.000 Requip 0.000 caffeine 0.000 Etilevodopa 0.000 Requip 0.000 CSF 0.000 BH4 0.000 Terguride 0.000 Tasmar 0.000 Lergotrile mesylate 0.000 Emsam 0.000 Quinpirole hydrochloride 0.000 Dopascan 0.000 Mazapertine succinate 0.000 D-CS 0.000 Spectrum 0.000 IPD 0.000 ROC 0.000 Benserazide hydrochloride 0.000 Apomorphine hydrochloride 0.000 Fluvoxamine maleate 0.000 Lergotrile 0.000 vitamin E 0.000 Glutathione 0.000 Rose oil 0.000 Parlodel 0.000 EMD 128130 0.000 Reserpine 0.000 Modafinil 0.000 Artane 0.000 7-Nitroindazole 0.000 Disipal 0.000 Flunarizine hydrochloride 0.000 Parlodel 0.000 Fluvoxamine maleate 0.000 Artane 0.000 Tocopherol 0.000 Dioscorea rhizome 0.000 NADH 0.000 Akineton 0.000 Haloperidol Decanoate 0.000 Brocresine 0.000 Bextra 0.000 Tianma 0.000 Glyceryl behenate 0.000 Disipal 0.000 L-tyrosine 0.000 ascorbate 0.000 more...

Enzyme tyrosine hydroxylase 0.008 MPP 0.006 complex I 0.001 glucocerebrosidase 0.001 monoamine oxidase 0.001 proteasome 0.000 DAT 0.000 DOPA decarboxylase 0.000 aromatic L-amino acid decarboxylase 0.000 caspase-3 0.000 Omi/HtrA2 0.000 superoxide dismutase 0.000 mitogen-activated protein kinase 0.000 acetylcholinesterase 0.000 catechol O-methyltransferase 0.000 neurosin 0.000 GTP cyclohydrolase I 0.000 protein kinase 0.000 isopeptidase 0.000 cholinesterase 0.000 ubiquitin-protein ligase 0.000 GSK 0.000 catalase 0.000 glutathione peroxidase 0.000 choline acetyltransferase 0.000 Thy1 0.000 ACS 0.000 NADPH oxidase 0.000 NADPH oxidase 0.000 CEP 0.000 cytochrome oxidase 0.000 HtrA2 protease 0.000 caspase-9 0.000 NQO1 0.000 CEP 0.000 ceruloplasmin 0.000 pantothenate kinase 0.000 ERK 0.000 proteinase K 0.000 PARP 0.000 AMP-activated protein kinase 0.000 cysteine-S-conjugate N-acetyltransferase 0.000 kynurenine 3-monooxygenase 0.000 succinate dehydrogenase 0.000 cyclohydrolase 0.000 NADH dehydrogenase 0.000 nicotinamide N-methyltransferase 0.000 alpha-ketoglutarate dehydrogenase 0.000 tyrosinase 0.000 lactate dehydrogenase 0.000 rhomboid protease 0.000 MEK 0.000 gamma-glutamylcysteine synthetase 0.000 diaphorase 0.000 luciferase 0.000 calcineurin 0.000 AMPK 0.000 NO synthase 0.000 TMT 0.000 protein phosphatase 2A 0.000 focal adhesion kinase 0.000 aldehyde dehydrogenase 0.000 aldehyde dehydrogenase 0.000 aldehyde dehydrogenase 0.000 glutathione reductase 0.000 GRK5 0.000 aldehyde dehydrogenase 0.000 cathepsin D 0.000 dopamine beta-hydroxylase 0.000 caspase-1 0.000 AMPK 0.000 tryptophan hydroxylase 0.000 ATPase 0.000 phosphatidylinositol 3-kinase 0.000 aconitase 0.000 botulinum neurotoxin 0.000 aldehyde dehydrogenase 0.000 peroxiredoxin 0.000 NOS 0.000 heme oxygenase 0.000 more...

Compound MPTP 0.031 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 0.021 L-DOPA 0.014 MPP 0.007 MPP 0.006 DBS 0.003 PDQ 0.002 Dopamine 0.002 Selegiline 0.001 Rotenone 0.001 4-phenyl-1,2,3,6-tetrahydropyridine 0.001 Dopa 0.001 Ropinirole 0.001 Entacapone 0.001 Tolcapone 0.001 Pergolide 0.001 6-Hydroxydopamine 0.000 CIT 0.000 CIT 0.000 1-Methyl-4-phenylpyridinium 0.000 glutamate 0.000 1,2,3,6-tetrahydropyridine 0.000 1,2,3,6-tetrahydropyridine 0.000 Amantadine 0.000 Amantadine 0.000 Amantadine 0.000 DAT 0.000 4-phenylpyridine 0.000 3,4-dihydroxyphenylalanine 0.000 Amantadine 0.000 oxygen 0.000 DOPAC 0.000 Paraquat 0.000 iron 0.000 1-benzyl-1,2,3,4-tetrahydroisoquinoline 0.000 Paraquat 0.000 1,2,3,4-tetrahydroisoquinoline 0.000 Cabergoline 0.000 Neuronal 0.000 Bromocriptine 0.000 Dec 0.000 Zonisamide 0.000 GABA 0.000 GABA 0.000 manganese 0.000 GSH 0.000 GSH 0.000 NMDA 0.000 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 0.000 5-HT 0.000 HVA 0.000 1-methyl-1,2,3,6-tetrahydropyridine 0.000 Carbidopa-levodopa 0.000 PSP 0.000 Clin 0.000 Rivastigmine 0.000 nitric oxide 0.000 coenzyme Q10 0.000 ATP 0.000 noradrenaline 0.000 Clozapine 0.000 3,4-Dihydroxyphenylacetaldehyde 0.000 calcium 0.000 Leucine 0.000 DNA 0.000 tyrosine 0.000 2-benzylidene-1-indanone 0.000 Adenosine 0.000 Memantine 0.000 Glutamate 0.000 caffeine 0.000 homocysteine 0.000 Methamphetamine 0.000 TNF 0.000 cysteine 0.000 N-acetylcysteine 0.000 Maneb 0.000 AMPA 0.000 leucine 0.000 Coenzyme Q10 0.000 more...

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