Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030567 (Parkinson's disease)
63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
synuclein 0.043
alpha-synuclein 0.034
LRRK2 0.011
parkin 0.010
leucine-rich repeat kinase 2 0.009
tyrosine hydroxylase 0.009
SNCA 0.008
DJ-1 0.007
Parkin 0.007
PINK1 0.007
MPP 0.007
dopamine transporter 0.004
STN 0.003
PARK2 0.003
DBS 0.003
PARK7 0.002
Leucine-rich repeat kinase 2 0.002
MAO-B 0.002
glucocerebrosidase 0.002
PARKIN 0.002
glial cell line-derived neurotrophic factor 0.002
ATP13A2 0.001
PARK6 0.001
PARK8 0.001
synphilin-1 0.001
CIT 0.001
alpha synuclein 0.001
Nurr1 0.001
GBA1 0.001
beta-synuclein 0.001
vesicular monoamine transporter 2 0.001
catechol-O-methyltransferase 0.001
dopa decarboxylase 0.001
Kufor-Rakeb syndrome 0.001
ubiquitin 0.001
neurotrophic factor 0.001
VPS35 0.001
prion 0.001
Synphilin-1 0.000
amyloid precursor protein 0.000
more...
Disease
Parkinson's disease 1.000
parkinsonism 0.029
Alzheimer's disease 0.012
dyskinesia 0.011
movement disorder 0.008
Dementia with Lewy bodies 0.007
Huntington's disease 0.006
dementia 0.006
progressive supranuclear palsy 0.005
akinesia 0.005
amyotrophic lateral sclerosis 0.004
abnormal involuntary movements 0.003
PARK2 0.003
REM sleep behavior disorder 0.002
PARK7 0.002
cognitive impairment 0.002
impulse control disorder 0.001
PARK8 0.001
hallucinations 0.001
PARK6 0.001
depression 0.001
multiple sclerosis 0.001
behavior disorder 0.001
camptocormia 0.001
Multiple system atrophy 0.001
PARK1 0.001
hemiparkinsonism 0.001
schizophrenia 0.001
neurological disease 0.001
restless legs syndrome 0.001
sleep disorders 0.000
hypersexuality 0.000
catalepsy 0.000
neuroblastoma 0.000
Essential tremor 0.000
psychosis 0.000
Pisa syndrome 0.000
stroke 0.000
Gaucher disease 0.000
pathological gambling 0.000
more...
Symptom
bradykinesia 0.019
tremor 0.011
motor symptom 0.004
dystonia 0.002
apathy 0.001
Rest tremor 0.000
muscle rigidity 0.000
visual hallucination 0.000
abnormal gait 0.000
sleepiness 0.000
Parkinsonian tremor 0.000
constipation 0.000
dysarthria 0.000
chorea 0.000
Involuntary Movement 0.000
drooling 0.000
Postural tremor 0.000
ataxia 0.000
insomnia 0.000
Parkinsonian rest tremor 0.000
functional recovery 0.000
myoclonus 0.000
pain 0.000
fatigue 0.000
Antecollis 0.000
cerebellar ataxia 0.000
intention tremor 0.000
blepharospasm 0.000
anosmia 0.000
dribbling saliva 0.000
eds 0.000
Motor dysfunction 0.000
Frozen gait 0.000
nausea 0.000
Hypometria 0.000
Persistent tremor 0.000
Pleurothotonus 0.000
Poverty of facial expression 0.000
Cog-wheel rigidity 0.000
Other hallucinations 0.000
more...
Drug
Parkin 0.007
Parkin 0.007
DBS 0.003
Sinemet 0.001
Sinemet 0.001
Rasagiline 0.001
Pramipexole 0.001
Pramipexole 0.001
Sinemet 0.001
Rotigotine 0.001
Madopar 0.001
Apomorphine 0.001
Eldepryl 0.000
Istradefylline 0.000
Eldepryl 0.000
Carbidopa 0.000
3,4-Dihydroxyphenylalanine 0.000
Azilect 0.000
MDS 0.000
Droxidopa 0.000
Mirapex 0.000
Lisuride 0.000
Comtan 0.000
Frontal 0.000
ROS 0.000
CFT 0.000
Permax 0.000
Permax 0.000
Zydis 0.000
Lazabemide 0.000
Zonisamide 0.000
Posture 0.000
Benserazide 0.000
Requip 0.000
caffeine 0.000
Etilevodopa 0.000
Requip 0.000
CSF 0.000
BH4 0.000
Terguride 0.000
more...
Enzyme
tyrosine hydroxylase 0.008
MPP 0.006
complex I 0.001
glucocerebrosidase 0.001
monoamine oxidase 0.001
proteasome 0.000
DAT 0.000
DOPA decarboxylase 0.000
aromatic L-amino acid decarboxylase 0.000
caspase-3 0.000
Omi/HtrA2 0.000
superoxide dismutase 0.000
mitogen-activated protein kinase 0.000
acetylcholinesterase 0.000
catechol O-methyltransferase 0.000
neurosin 0.000
GTP cyclohydrolase I 0.000
protein kinase 0.000
isopeptidase 0.000
cholinesterase 0.000
ubiquitin-protein ligase 0.000
GSK 0.000
catalase 0.000
glutathione peroxidase 0.000
choline acetyltransferase 0.000
Thy1 0.000
ACS 0.000
NADPH oxidase 0.000
NADPH oxidase 0.000
CEP 0.000
cytochrome oxidase 0.000
HtrA2 protease 0.000
caspase-9 0.000
NQO1 0.000
CEP 0.000
ceruloplasmin 0.000
pantothenate kinase 0.000
ERK 0.000
proteinase K 0.000
PARP 0.000
more...
Compound
MPTP 0.031
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 0.021
L-DOPA 0.014
MPP 0.007
MPP 0.006
DBS 0.003
PDQ 0.002
Dopamine 0.002
Selegiline 0.001
Rotenone 0.001
4-phenyl-1,2,3,6-tetrahydropyridine 0.001
Dopa 0.001
Ropinirole 0.001
Entacapone 0.001
Tolcapone 0.001
Pergolide 0.001
6-Hydroxydopamine 0.000
CIT 0.000
CIT 0.000
1-Methyl-4-phenylpyridinium 0.000
glutamate 0.000
1,2,3,6-tetrahydropyridine 0.000
1,2,3,6-tetrahydropyridine 0.000
Amantadine 0.000
Amantadine 0.000
Amantadine 0.000
DAT 0.000
4-phenylpyridine 0.000
3,4-dihydroxyphenylalanine 0.000
Amantadine 0.000
oxygen 0.000
DOPAC 0.000
Paraquat 0.000
iron 0.000
1-benzyl-1,2,3,4-tetrahydroisoquinoline 0.000
Paraquat 0.000
1,2,3,4-tetrahydroisoquinoline 0.000
Cabergoline 0.000
Neuronal 0.000
Bromocriptine 0.000
more...