Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030567 (Parkinson's disease)
 63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FGF20 protein 9.0
CENTB5 9.0
DnaJ (Hsp40) homolog, subfamily C, member 13 9.0
nuclear undecaprenyl pyrophosphate synthase 1 homolog 9.0
Coiled-coil domain-containing protein 154 9.0
DHX57 9.0
FLJ35379 9.0
discs, large (Drosophila) homolog-associated protein 3 9.0
parkin isoform 9.0
LOC644246 9.0
Cyclin G associated kinase 9.0
ZSCAN21 protein 9.0
centaurin beta5 9.0
C2orf58 9.0
CDCP2 9.0
LRRC37A2 9.0
F-box only protein 48 9.0
musashi 1 9.0
ZCRB1 9.0
DRD5P2 9.0
signal peptide peptidase-like 2B 9.0
GIGYF2 protein 9.0
transmembrane protein 175 9.0
OR52L1 9.0
DRD5P1 9.0
serine/threonine kinase 32B 9.0
EIF4G1 protein 9.0
peroxisomal biogenesis factor 3 9.0
EFHA2 9.0
TOMM7 9.0
synphilin-1A 9.0
non-SMC condensin I complex, subunit D2 9.0
PRR18 9.0
metallopeptidase M20 family 9.0
OR9A2 9.0
bridging integrator 3 9.0
neuron specific transcription factor 9.0
AMPK beta 1 9.0
Roco1 9.0
Parkinson disease (autosomal recessive, juvenile) 2, parkin 9.0
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Disease
Other degenerative diseases of the basal ganglia 9.0
PARK12 9.0
PARK10 9.0
Autosomal Recessive Parkinsonism 9.0
Pallidonigral degeneration 9.0
pathological emotionality 9.0
Extracampine hallucinations 9.0
Manic psychosis 9.0
Genetic Brain Disorders 9.0
Other mental retardation 9.0
PARK4 9.0
Explosive diarrhea 9.0
Parkinson's disease 9.0
Impairment of attention 9.0
Other extrapyramidal and movement disorders 9.0
Specific disorders of sleep 9.0
cortex; degeneration 9.0
Behavioral and emotional disorders with onset usually occurring in childhood and adolescence 9.0
PARK8 9.0
PARK1 8.9
PARK13 8.9
PARK5 8.8
PARK3 8.8
Hypokinetic dysarthria 8.8
PARK6 8.7
PARK11 8.6
Parkinson-dementia complex of Guam 8.5
Drug-induced dyskinesia 8.4
Parkinsonian crisis 8.4
PARK7 8.4
Juvenile Parkinsonism 8.3
Sleep attacks 8.3
Parkinson's disease and parkinsonism 8.3
PARK2 8.2
Pisa syndrome 8.2
camptocormia 8.1
REM sleep behavior disorder 8.1
abnormal involuntary movements 8.1
Dementia with Lewy bodies 8.0
impulse control disorder 8.0
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Symptom
Other hallucinations 9.0
Cog-wheel rigidity 9.0
Pleurothotonus 9.0
Poverty of facial expression 9.0
Persistent tremor 9.0
dribbling saliva 9.0
motor symptom 8.6
Rest tremor 8.5
bradykinesia 8.5
Frozen gait 8.4
Parkinsonian rest tremor 8.3
Antecollis 8.2
Ballismus 8.0
Hypometria 8.0
posthemiplegic chorea 8.0
Parkinsonian tremor 7.6
Postural tremor 7.5
Gustatory rhinorrhea 7.4
Senile tremor 7.4
Leg discomfort 7.4
visual hallucination 7.1
Limb dystonia 7.0
Retropulsion 6.9
Primary orthostatic tremor 6.7
amimia 6.7
impaired body balance 6.7
tremor 6.6
tactile hallucination 6.4
muscle rigidity 6.3
Motor dysfunction 6.2
Swallowing problems 6.0
dystonia 6.0
Involuntary Movement 6.0
abnormal gait 5.9
Respiratory dyskinesia 5.7
Tandem gait 5.7
apathy 5.6
drooling 5.5
feeling faint 5.4
intention tremor 5.4
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Drug
Etilevodopa 9.0
Emsam 9.0
Dopascan 9.0
D-CS 9.0
Mazapertine succinate 9.0
Quinpirole hydrochloride 9.0
Comtan 8.8
Mirapex 8.7
Istradefylline 8.6
Eldepryl 8.6
Permax 8.5
Permax 8.5
Rotigotine 8.4
Eldepryl 8.4
Rasagiline 8.4
Tasmar 8.4
Lazabemide 8.3
Droxidopa 8.3
Sinemet 8.2
Sinemet 8.2
Pramipexole 8.2
Pramipexole 8.1
Madopar 8.1
Azilect 8.1
Benserazide hydrochloride 8.0
Parkin 8.0
Parkin 7.9
DBS 7.7
Zydis 7.7
3,4-Dihydroxyphenylalanine 7.6
Requip 7.5
Requip 7.5
Lergotrile mesylate 7.4
EMD 128130 7.4
Sinemet 7.4
Carbidopa 7.2
Disipal 7.0
Flunarizine hydrochloride 7.0
Rose oil 6.8
Benserazide 6.8
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Enzyme
MPP 7.8
cysteine-S-conjugate N-acetyltransferase 7.4
HtrA2 protease 7.4
neurosin 7.4
glucocerebrosidase 6.7
tyrosine hydroxylase 6.6
aromatic L-amino acid decarboxylase 6.2
Omi/HtrA2 6.1
DAT 5.8
DOPA decarboxylase 5.7
catechol O-methyltransferase 5.7
complex I 5.5
carboxypeptidase 1 5.4
nicotinamide N-methyltransferase 5.2
monoamine oxidase 5.2
GTP cyclohydrolase I 5.2
isopeptidase 5.2
rhomboid protease 5.0
prenylated protein methyltransferase 5.0
proteasome ATPase 5.0
p-hydroxyphenylacetate 3-hydroxylase 4.9
kynurenine 3-monooxygenase 4.9
ubiquitin-protein ligase 4.9
pantothenate kinase 4.8
Aeromonas proteolytica aminopeptidase 4.8
3-hydroxyisobutyryl-CoA hydrolase 4.5
CEP 4.3
cyclohydrolase 4.3
Thy1 4.2
SDMT 4.2
AIR synthetase 4.2
methylmalonyl-CoA epimerase 4.0
phosphoethanolamine cytidylyltransferase 4.0
NQO2 4.0
kynurenine aminotransferase 3.9
proteasome 3.9
CEP 3.8
sepiapterin reductase 3.8
DAP II 3.8
MT 1 3.8
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Compound
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C9H9NO7 9.0
DNPD 9.0
C20H16N2O 9.0
2-(4-methylphenyl)-1H-indole 9.0
2-(4-methylphenyl)-1H-indole 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
C20H16N2O 9.0
1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione 9.0
C20H16N2O 9.0
Carbidopa-levodopa 8.6
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8.3
Ropinirole 8.3
MPTP 8.3
Entacapone 8.3
1-benzyl-1,2,3,4-tetrahydroisoquinoline 8.3
2-benzylidene-1-indanone 8.2
Tolcapone 8.2
Selegiline 8.1
PDQ 8.1
1-Methyl-4-phenylpyridinium 8.0
C19H17NO4 8.0
1-benzyl-3,4-dihydroisoquinoline 8.0
C10H10ClNO2 8.0
C19H17NO4 8.0
C10H10ClNO2 8.0
C19H17NO4 8.0
3,4-Dihydroxyphenylacetaldehyde 8.0
C19H17NO4 8.0
C19H17NO4 8.0
C10H10ClNO2 8.0
C10H10ClNO2 8.0
C19H17NO4 8.0
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