Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0030567 (Parkinson's disease)
63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein synuclein 3899 Sep 3688 Mol 3068 alpha-synuclein 3009 tyrosine hydroxylase 2917 ubiquitin 1141 dopamine transporter 1006 parkin 931 Parkin 914 MRI 849 MPP 843 olfactory 837 proteasome 827 LRRK2 826 DJ-1 763 caspase-3 741 PINK1 732 amyloid precursor protein 710 ATP 702 axonal 674 MAO-B 602 leucine-rich repeat kinase 2 587 SNCA 583 prion 560 glucocerebrosidase 507 endoplasmic reticulum 504 glial cell line-derived neurotrophic factor 488 lipopolysaccharide 480 superoxide dismutase 476 brain-derived neurotrophic factor 474 GABA 472 Bcl-2 444 GSH 440 neurotrophic factor 432 gut 427 glial fibrillary acidic protein 388 cytokine 384 DBS 378 TNF 363 STN 361 more...

Disease Parkinson's disease 63064 Alzheimer's disease 9103 parkinsonism 5149 dementia 4717 depression 3187 Huntington's disease 2328 amyotrophic lateral sclerosis 2096 cognitive impairment 1970 dyskinesia 1930 stroke 1716 multiple sclerosis 1570 movement disorder 1501 schizophrenia 1490 progressive supranuclear palsy 1035 cancer 1030 epilepsy 985 diabetes 869 neuroblastoma 867 Dementia with Lewy bodies 848 psychosis 836 akinesia 830 hallucinations 751 neurological disease 560 GSH 441 sleep disorders 438 ischemia 347 abnormal involuntary movements 338 hypertension 337 tumor 316 sleep disturbances 307 dysphagia 302 major depressive disorder 299 PARK2 295 autism 290 addiction 282 catalepsy 255 restless legs syndrome 249 REM sleep behavior disorder 246 Gaucher disease 239 behavior disorder 230 more...

Symptom tremor 3558 bradykinesia 1684 dystonia 1074 pain 890 sleepiness 458 apathy 389 fatigue 386 motor symptom 360 constipation 341 ataxia 277 seizures 273 insomnia 223 functional recovery 209 dysarthria 201 anesthesia 193 nausea 192 muscle rigidity 166 weakness 153 chorea 148 abnormal gait 137 headache 116 myoclonus 113 agitation 103 dizziness 98 cerebellar ataxia 96 discomfort 95 discomfort 92 vomiting 90 spasticity 85 thinning 80 visual hallucination 79 collapse 77 memory loss 66 syncope 63 anosmia 60 drooling 60 diarrhea 53 Involuntary Movement 51 cough 50 nausea and vomiting 50 more...

Drug Parkin 914 Parkin 914 DBS 378 ROS 285 CSF 259 caffeine 224 Apomorphine 201 Sinemet 174 MDS 155 Sinemet 141 Posture 131 lysine 130 vitamin E 129 Sinemet 127 Pramipexole 122 Pramipexole 113 NADH 106 Rasagiline 105 Spectrum 98 ascorbate 98 Frontal 97 ROC 93 Rotigotine 68 Glutathione 67 Madopar 63 BH4 56 Monit 49 CFT 49 Carbidopa 48 Dermatol 40 Zonisamide 36 L-tyrosine 31 3,4-Dihydroxyphenylalanine 30 Lisuride 29 Heme 28 MAP 27 Reserpine 27 IL-2 27 Eldepryl 26 ENT 26 more...

Enzyme tyrosine hydroxylase 2796 MPP 846 proteasome 831 complex I 817 monoamine oxidase 785 mitogen-activated protein kinase 725 superoxide dismutase 599 caspase-3 586 protein kinase 507 catalase 362 acetylcholinesterase 352 ACS 326 glucocerebrosidase 311 ERK 292 glutathione peroxidase 204 cholinesterase 191 DAT 161 ATPase 156 focal adhesion kinase 139 luciferase 136 lactate dehydrogenase 130 GSK 128 NADPH oxidase 120 NADPH oxidase 116 protein kinase C 113 DOPA decarboxylase 108 PARP 108 AMP-activated protein kinase 105 choline acetyltransferase 105 cytochrome oxidase 100 MEK 99 peroxidase 98 caspase-9 90 calcineurin 90 NO synthase 86 succinate dehydrogenase 77 aromatic L-amino acid decarboxylase 76 NQO1 76 tyrosinase 72 glutathione S-transferase 69 more...

Compound Dec 3840 MPTP 3217 L-DOPA 2869 Clin 2682 oxygen 2275 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2040 DNA 1551 iron 1322 glutamate 1276 Dopamine 1058 calcium 1022 MPP 843 MPP 843 ATP 702 water 702 nitric oxide 641 glucose 538 tyrosine 520 hydrogen 509 GSH 486 GSH 486 GABA 478 GABA 475 manganese 454 5-HT 418 cysteine 390 DBS 378 TNF 363 copper 357 noradrenaline 349 sodium 337 ACS 326 ACS 326 Neuronal 326 leucine 298 NMDA 298 serine 297 Dopa 281 CIT 278 CIT 274 more...

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