Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030567 (Parkinson's disease)
63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
synuclein 0.043
alpha-synuclein 0.034
LRRK2 0.011
parkin 0.010
leucine-rich repeat kinase 2 0.009
tyrosine hydroxylase 0.009
SNCA 0.008
DJ-1 0.007
Parkin 0.007
PINK1 0.007
MPP 0.007
dopamine transporter 0.004
STN 0.003
PARK2 0.003
DBS 0.003
PARK7 0.002
Leucine-rich repeat kinase 2 0.002
MAO-B 0.002
glucocerebrosidase 0.002
PARKIN 0.002
more...
Disease
Parkinson's disease 1.000
parkinsonism 0.029
Alzheimer's disease 0.012
dyskinesia 0.011
movement disorder 0.008
Dementia with Lewy bodies 0.007
Huntington's disease 0.006
dementia 0.006
progressive supranuclear palsy 0.005
akinesia 0.005
amyotrophic lateral sclerosis 0.004
abnormal involuntary movements 0.003
PARK2 0.003
REM sleep behavior disorder 0.002
PARK7 0.002
cognitive impairment 0.002
impulse control disorder 0.001
PARK8 0.001
hallucinations 0.001
PARK6 0.001
more...
Symptom
bradykinesia 0.019
tremor 0.011
motor symptom 0.004
dystonia 0.002
apathy 0.001
Rest tremor 0.000
muscle rigidity 0.000
visual hallucination 0.000
abnormal gait 0.000
sleepiness 0.000
Parkinsonian tremor 0.000
constipation 0.000
dysarthria 0.000
chorea 0.000
Involuntary Movement 0.000
drooling 0.000
Postural tremor 0.000
ataxia 0.000
insomnia 0.000
Parkinsonian rest tremor 0.000
more...
Drug
Parkin 0.007
Parkin 0.007
DBS 0.003
Sinemet 0.001
Sinemet 0.001
Rasagiline 0.001
Pramipexole 0.001
Pramipexole 0.001
Sinemet 0.001
Rotigotine 0.001
Madopar 0.001
Apomorphine 0.001
Eldepryl 0.000
Istradefylline 0.000
Eldepryl 0.000
Carbidopa 0.000
3,4-Dihydroxyphenylalanine 0.000
Azilect 0.000
MDS 0.000
Droxidopa 0.000
more...
Enzyme
tyrosine hydroxylase 0.008
MPP 0.006
complex I 0.001
glucocerebrosidase 0.001
monoamine oxidase 0.001
proteasome 0.000
DAT 0.000
DOPA decarboxylase 0.000
aromatic L-amino acid decarboxylase 0.000
caspase-3 0.000
Omi/HtrA2 0.000
superoxide dismutase 0.000
mitogen-activated protein kinase 0.000
acetylcholinesterase 0.000
catechol O-methyltransferase 0.000
neurosin 0.000
GTP cyclohydrolase I 0.000
protein kinase 0.000
isopeptidase 0.000
cholinesterase 0.000
more...
Compound
MPTP 0.031
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 0.021
L-DOPA 0.014
MPP 0.007
MPP 0.006
DBS 0.003
PDQ 0.002
Dopamine 0.002
Selegiline 0.001
Rotenone 0.001
4-phenyl-1,2,3,6-tetrahydropyridine 0.001
Dopa 0.001
Ropinirole 0.001
Entacapone 0.001
Tolcapone 0.001
Pergolide 0.001
6-Hydroxydopamine 0.000
CIT 0.000
CIT 0.000
1-Methyl-4-phenylpyridinium 0.000
more...