Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0030567 (Parkinson's disease)
 63,064 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
synuclein 3899
Sep 3688
Mol 3068
alpha-synuclein 3009
tyrosine hydroxylase 2917
ubiquitin 1141
dopamine transporter 1006
parkin 931
Parkin 914
MRI 849
MPP 843
olfactory 837
proteasome 827
LRRK2 826
DJ-1 763
caspase-3 741
PINK1 732
amyloid precursor protein 710
ATP 702
axonal 674
more...
Disease
Parkinson's disease 63064
Alzheimer's disease 9103
parkinsonism 5149
dementia 4717
depression 3187
Huntington's disease 2328
amyotrophic lateral sclerosis 2096
cognitive impairment 1970
dyskinesia 1930
stroke 1716
multiple sclerosis 1570
movement disorder 1501
schizophrenia 1490
progressive supranuclear palsy 1035
cancer 1030
epilepsy 985
diabetes 869
neuroblastoma 867
Dementia with Lewy bodies 848
psychosis 836
more...
Symptom
tremor 3558
bradykinesia 1684
dystonia 1074
pain 890
sleepiness 458
apathy 389
fatigue 386
motor symptom 360
constipation 341
ataxia 277
seizures 273
insomnia 223
functional recovery 209
dysarthria 201
anesthesia 193
nausea 192
muscle rigidity 166
weakness 153
chorea 148
abnormal gait 137
more...
Drug
Parkin 914
Parkin 914
DBS 378
ROS 285
CSF 259
caffeine 224
Apomorphine 201
Sinemet 174
MDS 155
Sinemet 141
Posture 131
lysine 130
vitamin E 129
Sinemet 127
Pramipexole 122
Pramipexole 113
NADH 106
Rasagiline 105
Spectrum 98
ascorbate 98
more...
Enzyme
tyrosine hydroxylase 2796
MPP 846
proteasome 831
complex I 817
monoamine oxidase 785
mitogen-activated protein kinase 725
superoxide dismutase 599
caspase-3 586
protein kinase 507
catalase 362
acetylcholinesterase 352
ACS 326
glucocerebrosidase 311
ERK 292
glutathione peroxidase 204
cholinesterase 191
DAT 161
ATPase 156
focal adhesion kinase 139
luciferase 136
more...
Compound
Dec 3840
MPTP 3217
L-DOPA 2869
Clin 2682
oxygen 2275
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2040
DNA 1551
iron 1322
glutamate 1276
Dopamine 1058
calcium 1022
MPP 843
MPP 843
ATP 702
water 702
nitric oxide 641
glucose 538
tyrosine 520
hydrogen 509
GSH 486
more...