Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0030567 (Parkinson's disease)
 63,064 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Bell's phenomenon (upward and outward rolling of the eyeballs on forcible closure of the eyelids) was studied in normal adults and in patients suffering from Parkinson's disease. Advancing age correlates with diminution of the response but this was more severe in Parkinson's disease and was thus shown to be suppressive of the normal mechanism. Asymmetrical responses, the right eye being nearly always more affected, were frequently encountered in both groups though more numerous in Parkinsonism. There was a tendency toward a lesser incidence of Bell's phenomenon in the more advanced stages of the disease but without a clearcut correlation.
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PMID:Bell's phenomenon in normal adults and in Parkinson's disease. 721 Nov 61

We analyzed the intended voluntary movement and simultaneously occurring automatic associated movement in Parkinson's disease(PD). We studied wrist dorsiflexion as a movement associated with grip and Bell's phenomenon(upward rolling of the eyeballs on forcible closure of the eyelids) in patients with PD and normal controls. The patients showed significantly smaller wrist dorsiflexion and upward rolling of the eyeballs. Patients with PD have a greater reduction of automatic associated movement than intended voluntary movement. This discrepancy between the associated movement and voluntary movement may be one of the bases of clinical symptoms of PD patients in early stage.
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PMID:[Impaired associated movement in Parkinson's disease]. 901 46