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Query: UMLS:C0030552 (paresis)
 5,831 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Progressive supranuclear palsy, first described as clinical entity by Steele, Richardson and Olszewski, is a degenerative disorder of the central nervous system. Besides progressive supranuclear oculomotor disturbances, other characteristic signs are pseudobulbar paresis, axial rigidity, gait disturbances and subcortical dementia. Misinterpretation in the early stage as Parkinson's disease is frequently seen. A causal therapy is still missing.
Schweiz Rundsch Med Prax 1992 Dec 15
PMID:[Progressive supranuclear palsy]. 147 Jul 96

Burkitt's lymphoma (BL) cell lines estimated in a previous study as having a high, low and no tumourigenicity (7) were intravenously (i.v.) injected into preirradiated (480 rad) nude mice. BL cell lines with a high tumourigenic potential produced metastatic tumours in the brain, spinal cord, bone marrow, stomach and kidney, but did not disseminate into the lung, liver, ovary and spleen. The survival time of the tumour bearing animals ranged from 2 to 10 weeks. The majority of mice i.v. injected with highly tumourigenic BL cell lines showed paresis or paralysis of the hind legs. This was associated with the presence of neoplastic nodules either in the brain and/or in the spinal cord. In animals with metastasis to the stomach and kidney progressive cachexia was observed. The described experimental model of metastatic BL tumours in nude mice can effectively be used for the in vivo study of new therapeutic molecules such as monoclonal antibodies coupled or not to substances, toxic to tumour cells. This model can also be useful for the identification and analysis of homing properties of BL cells and their implication in BL pathogenesis.
Exp Toxicol Pathol 1992 Dec
PMID:Metastatic capacity of Burkitt's lymphoma cell lines in nude mice. 147 17

Five patients with superficial anterior cerebral artery territory infarcts in the paracentral area are reported, who developed a hemiparesis which was predominant in the leg, and with homolateral ataxia in the arm. A similar neurological picture was not observed in 1736 patients who were admitted over an eight year period to a primary care stroke centre with their first stroke. Involvement of corticopontine fibres at their origin, together with damage to the lower limb motor strip or underlying white matter, appears to have been the cause of a clinical syndrome (homolateral ataxia and crural paresis) which has been ascribed to lacunar infarction.
J Neurol Neurosurg Psychiatry 1992 Dec
PMID:Homolateral ataxia and crural paresis: a syndrome of anterior cerebral artery territory infarction. 147 93

Data concerning the fractionation sensitivity of normal tissues during radiation retreatment are limited. Experiments were performed to investigate whether the fractionation sensitivity of the rat cervical spinal cord is changed during retreatment 6 months after a first dose of 15 Gy, representing about half the biologically effective dose for induction of paresis. After a 6 months interval, the long-term recovery from the first treatment was about 45%. The fractionation sensitivity of the rat cervical spinal cord during reirradiation was not significantly different from the fractionation sensitivity of not previously irradiated control rats, with an alpha/beta ratio of 2.3 Gy in control rats and 1.9 Gy during reirradiation of the spinal cord. An additional observation from these experiments was the presence of incomplete repair after fractionated treatment with 2 fractions of 3 Gy per day with 10-h intervals.
Radiother Oncol 1992 Dec
PMID:Fractionation sensitivity of the rat cervical spinal cord during radiation retreatment. 148 Jul 76

Five patients with acquired monocular elevation paresis were investigated using direct current electroculography. With recovery, upward saccade velocities significantly increased in both eyes in all patients. The gain of upward-following eye movements significantly increased in the paretic eye of all patients and in the opposite eye of four patients. These findings are interpreted in terms of an asymmetric upgaze palsy which clinically presented as monocular elevation paresis in the more severely affected eye. A brainstem lesion contralateral to monocular elevation paresis was suggested in four patients by contralateral Horner's syndrome and contralateral abduction paresis, each in one patient, and contralateral ptosis in two patients. In only one patient, computerized tomography and magnetic resonance imaging substantiated a contralateral meso-diencephalic lesion.
Brain 1992 Dec
PMID:Acquired monocular elevation paresis. An asymmetric upgaze palsy. 148 67

Since the advent of antibiotics, otogenic complications have decreased considerably. However, incomplete antibiotic therapy has altered the clinical course of middle ear disease so as to be more insidious. This paper reports a case of Bezold's abscess associated with cholesteatoma. A 48-year-old man visited our hospital presenting with a 4-day history of right otorrhea and a tender swelling in the right neck. Physical examination showed a febrile patient (38.8 degrees C) with right facial paresis and trismus. A hyperemic, hard and tender swelling was observed in his right neck from the lateral cervical to the mental region. The tympanic membrane was invisible because of granulation and swelling of the posterior wall of the external auditory canal. Intravenous clindamycin and ceftazidime therapy was started immediately. A CT-scan revealed a diffuse shadow with bony destruction in the right mastoid cortex. Extensive abscess formation was also found in the right sternocleidomastoid muscle, in the anterior neck and in the posterior neck. He was diagnosed as having Bezold's abscess associated with cholesteatoma. Radical mastoidectomy and drainage of the neck abscess was performed on the third day under general anesthesia. The mastoid cavity was found to be filled with pus and cholesteatoma debris. A small area of defective bone was found at the mastoid tip, through which there were communications between the mastoid cavity and the abscesses in the neck. Bony destruction was also found in the horizontal and vertical portion of the facial canal. Bacteroides and three kinds of gram-negative rods were cultured from the mastoid cavity.(ABSTRACT TRUNCATED AT 250 WORDS)
Nihon Jibiinkoka Gakkai Kaiho 1992 Dec
PMID:[A case of Bezold's abscess associated with cholesteatoma]. 149 Dec 72

The incidence of neurological deficits of the upper extremity was studied in a prospective trial on 201 consecutive patients who underwent median sternotomy at cardiac surgery. In 13 patients (6.5%), a brachial plexus paresis was diagnosed postoperatively. We were unable to demonstrate any statistically significant correlation between brachial plexus paresis and the side of arm placement, the side of cannulation of the jugular vein, the duration of operation, the bypass time, sex, or type of operation. All patients who suffered from neurological deficit were aged 50 years and more, however without any statistically significant correlation. In our opinion, brachial plexus lesions following median sternotomy in cardiac surgery depend on the extent of sternal spread and the height of placement of the retractor in dependence of the rigidity of the rib cage. By reason of the iatrogenic cause of brachial plexus lesions, it appears to us that these complications should be included in those of which the patient needs to be informed preoperatively.
Thorac Cardiovasc Surg 1991 Dec
PMID:Brachial plexus lesions following median sternotomy in cardiac surgery. 166 91

The investigations were carried out to evaluate potential side effects of a prophylaxis with high doses of vitamin D3 and vitamin D metabolites in parturient paresis. For this reason, 10(7) IU vitamin D3 (= 250 mg), 4 mg 25-OHD3 or 420 micrograms 1 alpha-OHD3 were applied to non-gravid dairy cows at the end of lactation. The application was repeated 3 times at one week intervals and the changes of the mineral concentration and 25-OHD were measured in the plasma. The pathomorphological changes in the cardio-vascular system and other organs were examined macro- and microscopically. The application of vitamin D3 and 25-OHD3 led to an immediate and continuous increase of the 25-OHD concentration in the plasma. On the other hand, administration of 1 alpha-OHD3 resulted in a decrease of the 25-OHD level. After the application of vitamin D3 and 1 alpha-OHD3, the Ca and Pi concentration increased significantly. After 25-OHD3, the Ca concentration decreased below the initial level in the second week. The administration of all 3 compounds led to a significant decrease of the Mg concentration after the first injection. The administration of vitamin D3 and 1 alpha-OHD3 resulted in a significantly more pronounced calcinosis of inner organs while after the application of 25-OHD3 only occasionally calcium deposits were observed in the vascular system.
Zentralbl Veterinarmed A 1991 Dec
PMID:The effects of intramuscularly administered vitamin D3, 25- and 1 alpha-hydroxycholecalciferol in cows on plasma mineral content, plasma 25-hydroxycholecalciferol and on mineral deposits in soft tissues. 166 30

A 65-year-old woman who has been admitted after organophosphate-induced poisoning (Fenthion), develops pareses as a result of neuromuscular junctional dysfunction 7 days post-exposure. These findings are consistent with an intermediate syndrome, which may appear within 24 to 96 hours of exposure and subsides after 5 to 18 days. Delayed polyneuropathy develops within 1 to 3 weeks and abates after 6 to 12 months. A distal axonopathy can be demonstrated. Several authors have attempted EMG monitoring of pesticide-workers in agricultural and industrial settings. The electrophysiologic examination is an important diagnostic adjunct in the development and course of muscle paresis following organophosphate-ester poising.
Electromyogr Clin Neurophysiol 1991 Dec
PMID:The neurophysiologic examination in organophosphate ester poisoning. Case report and review of the literature. 166 80

A 48-year-old female suffered from severe headache, vomiting, and disturbance of consciousness. On admission, she was somnolent with mild paresis of the left leg. Precontrast computed tomography (CT) scans showed a high-density area in the left sylvian fissure and the posterior horn of the left lateral ventricle. Angiographically, a right middle cerebral artery aneurysm and a basilar artery aneurysm were recognized. Furthermore, on the venous phase of bilateral carotid angiograms, superior sagittal sinus (SSS) thrombosis was recognized. Subarachnoid hemorrhage (SAH) was probably induced by rupture of a dilated vein associated with SSS thrombosis, because high-density area on CT scan and location of the aneurysms were different. The patient was initially treated conservatively. Two months later, craniotomy was performed which did not disclose any trace of hemorrhage around the aneurysms and aneurysms themselves. Postoperatively, acute brain swelling and generalized convulsion were induced. The patient became ambulatory 5 months after surgery. In SAH cases, the venous phase should be examined at least in one side of the carotid arteries. In such a SAH case induced by venous thrombosis complicated by aneurysms it is very difficult to decide the timing of surgery for aneurysms.
Neurol Med Chir (Tokyo) 1991 Dec
PMID:[Superior sagittal sinus thrombosis complicated with multiple aneurysms presenting as subarachnoid hemorrhage. Case report]. 172 64


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